G protein signaling (Homo sapiens)
From WikiPathways
Description
G proteins, short for guanine nucleotide-binding proteins, are a family of proteins involved in second messenger cascades.
G proteins are so called because they function as "molecular switches". They alternate from 'inactive' guanosine diphosphate (GDP) to 'active' guanosine triphosphate (GTP), which is a binding state, and which proceeds to regulate downstream cell processes.
Source: Wikipedia
Proteins on this pathway have targeted assays available via the CPTAC Assay PortalQuality Tags
Ontology Terms
Pathway Ontology : MAPK signaling pathway mitogen activated protein kinase signaling pathway
Bibliography
- Neves SR, Ram PT, Iyengar R; ''G protein pathways.''; Science, 2002 PubMed Europe PMC Scholia
- Stryer L, Bourne HR; ''G proteins: a family of signal transducers.''; Annu Rev Cell Biol, 1986 PubMed Europe PMC Scholia
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External references
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Annotated Interactions
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