Meta pathway lipodystrophy, dyslipidemia and hyperlipidemia (Homo sapiens)
From WikiPathways
Description
Dyslipidemia is a change (either increase or decrease) of adipose levels within the blood. When there is a significant increase of this, the term hyperlipidemia is used. With a significant decrease, we talk about hypolipoproteinemia. Both hyperlipidemia and hypolipoproteinemia can be classified as either acquired or familial.
Familial hyperlipidemia can be classified in five types according to the Fredrickson classification.For this classification see Quispe et al. 2019 https://doi.org/10.5114/aoms.2019.87207.
Lipodystrophy is a change (either increase or decrease) of adipose levels within the lipid tissue deposits. Lipodystrophy is classified based on wether the disease is acquired or congenital, but also wether it is geralized (through the entire body) or partial (in specific parts of the body). This classification was based on the following information by Akinci et al. [1]Quality Tags
Ontology Terms
Bibliography
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- Davidson, MH, Pulipati, VP; ''Hypolipidemia''; MSD MANUAL Professional Version, https://www.msdmanuals.com/professional/endocrine-and-metabolic-disorders/lipid-disorders/hypolipidemia, 2019
- Geller AS, Polisecki EY, Diffenderfer MR, Asztalos BF, Karathanasis SK, Hegele RA, Schaefer EJ; ''Genetic and secondary causes of severe HDL deficiency and cardiovascular disease.''; J Lipid Res, 2018 PubMed Europe PMC Scholia
- Akinci B, Sahinoz M, Oral E; ''Lipodystrophy Syndromes: Presentation and Treatment''; , 2000 PubMed Europe PMC Scholia
- Garg A; ''Clinical review#: Lipodystrophies: genetic and acquired body fat disorders.''; J Clin Endocrinol Metab, 2011 PubMed Europe PMC Scholia
- Berglund L, Brunzell JD, Goldberg AC, Goldberg IJ, Sacks F, Murad MH, Stalenhoef AF; ''Evaluation and treatment of hypertriglyceridemia: an Endocrine Society clinical practice guideline.''; J Clin Endocrinol Metab, 2012 PubMed Europe PMC Scholia
- Chait A, Brunzell JD; ''Acquired hyperlipidemia (secondary dyslipoproteinemias).''; Endocrinol Metab Clin North Am, 1990 PubMed Europe PMC Scholia
- Quispe R, Hendrani AD, Baradaran-Noveiry B, Martin SS, Brown E, Kulkarni KR, Banach M, Toth PP, Brinton EA, Jones SR, Joshi PH; ''Characterization of lipoprotein profiles in patients with hypertriglyceridemic Fredrickson-Levy and Lees dyslipidemia phenotypes: the Very Large Database of Lipids Studies 6 and 7.''; Arch Med Sci, 2019 PubMed Europe PMC Scholia
- Welty FK; ''Hypobetalipoproteinemia and abetalipoproteinemia.''; Curr Opin Lipidol, 2014 PubMed Europe PMC Scholia
History
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External references
DataNodes
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Name | Type | Database reference | Comment |
---|---|---|---|
Acquired partial lipodystrophy | Pathway | WP5104 (WikiPathways) | |
Congenital generalized lipodystrophy (CGL) | Pathway | WP5101 (WikiPathways) | |
Dyslipidemia | Q66291209 (Wikidata) | DISEASE | |
Familial partial lipodystrophy (FPLD) | Pathway | WP5102 (WikiPathways) | |
Hyperlipidemia | Q1079120 (Wikidata) | DISEASE | |
Hypolipoproteinemia | Q5959735 (Wikidata) | DISEASE | |
Lipodystrophy | Q1538213 (Wikidata) | DISEASE | |
Progeria associated lipodystrophy | Pathway | WP5103 (WikiPathways) | |
Type III | Pathway | WP5110 (WikiPathways) | |
Type II | Pathway | WP5109 (WikiPathways) | |
Type IV | Pathway | WP5111 (WikiPathways) | |
Type I | Pathway | WP5108 (WikiPathways) | |
Type V | Pathway | WP5112 (WikiPathways) |
Annotated Interactions
No annotated interactions