Histidine biosynthesis (Saccharomyces cerevisiae)

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1-3L-glutamateL-histidinol phosphatepyrophosphatephosphatepyrophosphateHIS4H+NADHHIS4HIS4ATPHIS1L-glutamatePhosphoribulosylformimino-AICAR-PHistidinolHIS4D-erythro-imidazole-glycerol-phosphate NADHPRPPHIS6Phosphoribosyl-ATPHIS5HIS3NADHistidinalH2OHIS2L-glutamine2-oxoglutarateAICARimidazole acetol-phosphateL-histidineHIS7Phosphoribosyl-AMPPhosphoribosylformimino-AICAR-PhosphateH2OH2OH2OH2ONADH+


Description

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Ontology Terms

 

Bibliography

  1. Rébora K, Laloo B, Daignan-Fornier B; ''Revisiting purine-histidine cross-pathway regulation in Saccharomyces cerevisiae: a central role for a small molecule.''; Genetics, 2005 PubMed Europe PMC Scholia
  2. Alifano P, Fani R, Liò P, Lazcano A, Bazzicalupo M, Carlomagno MS, Bruni CB; ''Histidine biosynthetic pathway and genes: structure, regulation, and evolution.''; Microbiol Rev, 1996 PubMed Europe PMC Scholia
  3. Denis V, Boucherie H, Monribot C, Daignan-Fornier B; ''Role of the myb-like protein bas1p in Saccharomyces cerevisiae: a proteome analysis.''; Mol Microbiol, 1998 PubMed Europe PMC Scholia
  4. ''L-histidine biosynthesis''; YeastPathways,

History

View all...
CompareRevisionActionTimeUserComment
135454view22:16, 5 September 2024KhanspersModified description
135453view22:09, 5 September 2024Khanspers
135452view22:08, 5 September 2024Khanspersadded lit ref
135310view18:53, 16 August 2024KhanspersOntology Term : 'classic metabolic pathway' added !
135309view18:52, 16 August 2024KhanspersModified description
135308view18:52, 16 August 2024Khanspersmetabolite ids, interactions, layout
117300view11:16, 20 May 2021EweitzModified title
93001view18:23, 21 July 2017KhanspersModified description
93000view18:23, 21 July 2017Khanspersremoved GenMAPP notes
92888view09:47, 14 July 2017Jeffrey GoessensFixed some interactions
85639view16:17, 4 June 2016EgonwFixed the CAS number.
71894view10:22, 22 October 2013Mkutmonchanged AICAR to metabolite
70264view21:47, 15 July 2013MaintBotupdated to 2013 schema
69939view20:13, 11 July 2013EgonwMarked a few DataNodes with CAS registry numbers as metabolites.
67337view10:39, 26 June 2013Christine ChichesterOntology Term : 'histidine biosynthetic pathway' added !
41801view04:48, 2 March 2011MaintBotRemoved redundant pathway information and comments
36660view22:53, 9 April 2010MaintBot
36621view22:32, 9 April 2010MaintBotDescription and bibliography added from SGD
21760view11:32, 14 November 2008MaintBot[[Pathway:Saccharomyces cerevisiae:Histidine Biosynthesis]] moved to [[Pathway:WP514]]: Moved to stable identifier
12748view08:00, 17 May 2008MaintBotautomated metabolite conversion
8783view14:09, 7 January 2008MaintBotAdded to category $category
8781view14:09, 7 January 2008M.BraymerUploaded new pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
2-oxoglutarateMetaboliteCHEBI:16810 (ChEBI)
AICARMetabolite3031-94-5 (CAS)
ATPMetabolite1927-31-7 (CAS)
D-erythro-imidazole-glycerol-phosphate Metabolite58278 (ChEBI)
H+Metabolite15378 (ChEBI)
H2OMetaboliteHMDB02111 (HMDB)
HIS1GeneProductS000000857 (SGD)
HIS2GeneProductS000001921 (SGD)
HIS3GeneProductS000005728 (SGD)
HIS4GeneProductS000000535 (SGD)
HIS5GeneProductS000001378 (SGD)
HIS6GeneProductS000001282 (SGD)
HIS7GeneProductS000000452 (SGD)
HistidinalMetaboliteHMDB12234 (HMDB)
HistidinolMetaboliteHMDB03431 (HMDB)
L-glutamateMetabolite56-86-0 (CAS)
L-glutamineMetabolite56-85-9 (CAS)
L-histidineMetabolite71-00-1 (CAS)
L-histidinol phosphateMetabolite57980 (ChEBI)
NADMetabolite57540 (ChEBI)
NADHMetabolite53-84-9 (CAS)
PRPPMetabolite97-55-2 (CAS)
Phosphoribosyl-AMPMetaboliteHMDB12276 (HMDB)
Phosphoribosyl-ATPMetaboliteHMDB03665 (HMDB)
Phosphoribosylformimino-AICAR-PhosphateMetabolite58435 (ChEBI)
Phosphoribulosylformimino-AICAR-PMetaboliteHMDB12278 (HMDB)
imidazole acetol-phosphateMetabolite57766 (ChEBI)
phosphateMetabolite14265-44-2 (CAS)
pyrophosphateMetabolite2466-09-3 (CAS)

Annotated Interactions

No annotated interactions

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