T-cell receptor signaling (Homo sapiens)

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Proteolytic cleavagePlasma membraneEndosomeCY->PMLigandECEndoplasmic reticulumDeubiquitinationCY->NUAutophosphorylationNU->CYGOAccession Number: NetPath_11NucleusCYExtracellularCY->NUEnzyme complexUbiquitinationDAcetylationENMolecule in the pathwayProteins in a complex interactionMolecular associationDesumoylationSumoylationTranslocationCytoplasmDeacetylationActivationMethylation(Protein-protein interaction)DGene SymbolReaction through unknown mechanisms/moleculesInhibitionDemethylationMitochondrionReceptorERAntigenPalmitoylationGolgi apparatusPMDephosphorylationRecruitmentNUGlycosylationMTPhosphorylationControlPTPRHPAK1MAPK3CREB1SCAP1RAPGEF1PIK3R2CRKLGAB2PAG1PTPN22GRB2PTPN11EVLCD3ZCDC42PPP3CBGRAP2FCRL3RAC2PTPN3DOCK2LIME1PTPN6SH3BP2FOSITPR1RIPK2FYBNCLNFAM1ARHGEF7UNC119ZAP70SOS2STAT5BCD3DSLA2AKT1MAP4K1WASENAHCISHJAK3CD8AGRAPABI1LIME1CD2STAT5BGIT2MAP2K2CREBBPKHDRBS1SHC1DTX1BRAFCD3ZMAPK7PTPRCLNKVASPPIK3R1LAX1HOMER3LCKSTK39CBLBCARD11TUBA1NCK1NCK1PTK2BFYBCD3ESIT1PSTPIP1LCP2MAP3K1CD5DNM2CEBPBSTAT5ARAP1AABL1PTPN12RASGRP2DUSP3YWHAQCABIN1TRA@DBNLSRCHDAC7ATRB@LCP2HDAC7AWASF2MAP2K1CD3ECRKSH2D3CPRKD2PRKCQRASA1PTK2SLATRAT1TXKDLG1JUNCBLSTAT5APLCG1PTPRJPXNACP1ARHGDIBJUNDEF6CTNNB1VAV2CD4ARHGEF6LATVAV1CD2APFYNSTAT1SOS1MAPK1SCAP2LYNNEDD9WASPIPSHBITKSH2D2AVAV3MUC1BCL10SYKNFATC2CD3GTUBB


Description

No description

Comments

GenMAPP notes 
NetPath_11 - T Cell Receptor Signaling Pathway NetPath (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the NetPath website until the pathway is published.
GenMAPP remarks 
http://www.netpath.org

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
135175view01:47, 7 August 2024EweitzRefine legend
135174view01:46, 7 August 2024EweitzEconomize layout
129712view01:31, 22 May 2024EweitzModified title
126222view06:22, 17 April 2023EgonwLicense is CCZero
120966view05:52, 4 February 2022EgonwModified title
120700view13:15, 23 December 2021EweitzStandardize font, weight, case
116404view09:02, 7 May 2021EweitzModified title
103503view17:45, 7 March 2019AlexanderPicoFixed Entrez ID for LCK
97623view07:50, 31 May 2018AMTanOntology Term : 'T cell' added !
89937view13:49, 6 October 2016MkutmonModified description
86031view12:16, 28 June 2016EveloModified title
84986view18:55, 4 April 2016AlexanderPicoreplaced mim-conversion with arrow for generic
79955view12:06, 28 April 2015Zarichanged Entrez gene Id to Ensembl Id for MAP3K14
79954view12:05, 28 April 2015ZariChanged Entrez gene Id to Ensembl Id
72111view22:22, 24 October 2013AlexanderPicoadded missing database to xref
70116view19:14, 12 July 2013MaintBotupdated to 2013 schema
48452view16:31, 24 May 2012NetPathModified description
48451view16:27, 24 May 2012NetPathModified description
45093view21:13, 6 October 2011KhanspersOntology Term : 'T cell receptor signaling pathway' added !
44619view17:47, 22 September 2011KhanspersUpdating content to NetSlim
41061view23:17, 1 March 2011MaintBotRemoved redundant pathway information and comments
20823view11:30, 14 November 2008MaintBot[[Pathway:Homo sapiens:T-Cell-Receptor NetPath 11]] moved to [[Pathway:WP69]]: Moved to stable identifier
11464view11:13, 1 April 2008ThomasModified categories
11159view10:30, 22 March 2008MaintBotNew page: 8426view13:46, 7 January 2008MaintBot[[Pathway:Human:T-Cell-Receptor NetPath 11]] moved to [[Pathway:Homo sapiens:T-Cell-Receptor NetPath 11]]: Renaming species
7830view16:20, 18 December 2007MaintBotfixed category names
7298view12:42, 4 November 2007MaintBotAdded categories to GPML
6396view22:18, 22 May 2007A.Pandeygpml file for [[Human:T-Cell-Receptor_NetPath_11]]

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ABI1GeneProduct10006 (Entrez Gene)
ABL1GeneProduct25 (Entrez Gene)
ACP1GeneProduct52 (Entrez Gene)
AKT1GeneProduct207 (Entrez Gene)
ARHGDIBGeneProduct397 (Entrez Gene)
ARHGEF6GeneProduct9459 (Entrez Gene)
ARHGEF7GeneProduct8874 (Entrez Gene)
BCL10GeneProduct8915 (Entrez Gene)
BRAFGeneProduct673 (Entrez Gene)
CABIN1GeneProduct23523 (Entrez Gene)
CARD11GeneProduct84433 (Entrez Gene)
CBLGeneProduct867 (Entrez Gene)
CBLBGeneProduct868 (Entrez Gene)
CD2GeneProduct914 (Entrez Gene)
CD2APGeneProduct23607 (Entrez Gene)
CD3DGeneProduct915 (Entrez Gene)
CD3EGeneProduct916 (Entrez Gene)
CD3GGeneProduct917 (Entrez Gene)
CD3ZGeneProduct919 (Entrez Gene)
CD4GeneProduct920 (Entrez Gene)
CD5GeneProduct921 (Entrez Gene)
CD8AGeneProduct925 (Entrez Gene)
CDC42GeneProduct998 (Entrez Gene)
CEBPBGeneProduct1051 (Entrez Gene)
CISHGeneProduct1154 (Entrez Gene)
CREB1GeneProduct1385 (Entrez Gene)
CREBBPGeneProduct1387 (Entrez Gene)
CRKGeneProduct1398 (Entrez Gene)
CRKLGeneProduct1399 (Entrez Gene)
CTNNB1GeneProduct1499 (Entrez Gene)
DBNLGeneProduct28988 (Entrez Gene)
DEF6GeneProduct50619 (Entrez Gene)
DLG1GeneProduct1739 (Entrez Gene)
DNM2GeneProduct1785 (Entrez Gene)
DOCK2GeneProduct1794 (Entrez Gene)
DTX1GeneProduct1840 (Entrez Gene)
DUSP3GeneProduct1845 (Entrez Gene)
ENAHGeneProduct55740 (Entrez Gene)
EVLGeneProduct51466 (Entrez Gene)
FCRL3GeneProduct115352 (Entrez Gene)
FOSGeneProduct2353 (Entrez Gene)
FYBGeneProduct2533 (Entrez Gene)
FYNGeneProduct2534 (Entrez Gene)
GAB2GeneProduct9846 (Entrez Gene)
GIT2GeneProduct9815 (Entrez Gene)
GRAPGeneProduct10750 (Entrez Gene)
GRAP2GeneProduct9402 (Entrez Gene)
GRB2GeneProduct2885 (Entrez Gene)
HDAC7AGeneProduct51564 (Entrez Gene)
HOMER3GeneProduct9454 (Entrez Gene)
ITKGeneProduct3702 (Entrez Gene)
ITPR1GeneProduct3708 (Entrez Gene)
JAK3GeneProduct3718 (Entrez Gene)
JUNGeneProduct3725 (Entrez Gene)
KHDRBS1GeneProduct10657 (Entrez Gene)
LATGeneProduct27040 (Entrez Gene)
LAX1GeneProduct54900 (Entrez Gene)
LCKGeneProduct3932 (Entrez Gene)
LCP2GeneProduct3937 (Entrez Gene)
LIME1GeneProduct54923 (Entrez Gene)
LNKGeneProduct10019 (Entrez Gene)
LYNGeneProduct4067 (Entrez Gene)
MAP2K1GeneProduct5604 (Entrez Gene)
MAP2K2GeneProduct5605 (Entrez Gene)
MAP3K1GeneProduct4214 (Entrez Gene)
MAP4K1GeneProduct11184 (Entrez Gene)
MAPK1GeneProduct5594 (Entrez Gene)
MAPK3GeneProduct5595 (Entrez Gene)
MAPK7GeneProduct5598 (Entrez Gene)
MUC1GeneProduct4582 (Entrez Gene)
NCK1GeneProduct4690 (Entrez Gene)
NCLGeneProduct4691 (Entrez Gene)
NEDD9GeneProduct4739 (Entrez Gene)
NFAM1GeneProduct150372 (Entrez Gene)
NFATC2GeneProduct4773 (Entrez Gene)
PAG1GeneProduct55824 (Entrez Gene)
PAK1GeneProduct5058 (Entrez Gene)
PIK3R1GeneProduct5295 (Entrez Gene)
PIK3R2GeneProduct5296 (Entrez Gene)
PLCG1GeneProduct5335 (Entrez Gene)
PPP3CBGeneProduct5532 (Entrez Gene)
PRKCQGeneProduct5588 (Entrez Gene)
PRKD2GeneProduct25865 (Entrez Gene)
PSTPIP1GeneProduct9051 (Entrez Gene)
PTK2GeneProduct5747 (Entrez Gene)
PTK2BGeneProduct2185 (Entrez Gene)
PTPN11GeneProduct5781 (Entrez Gene)
PTPN12GeneProduct5782 (Entrez Gene)
PTPN22GeneProduct26191 (Entrez Gene)
PTPN3GeneProduct5774 (Entrez Gene)
PTPN6GeneProduct5777 (Entrez Gene)
PTPRCGeneProduct5788 (Entrez Gene)
PTPRHGeneProduct5794 (Entrez Gene)
PTPRJGeneProduct5795 (Entrez Gene)
PXNGeneProduct5829 (Entrez Gene)
RAC2GeneProduct5880 (Entrez Gene)
RAP1AGeneProduct5906 (Entrez Gene)
RAPGEF1GeneProduct2889 (Entrez Gene)
RASA1GeneProduct5921 (Entrez Gene)
RASGRP2GeneProduct10235 (Entrez Gene)
RIPK2GeneProduct8767 (Entrez Gene)
SCAP1GeneProduct8631 (Entrez Gene)
SCAP2GeneProduct8935 (Entrez Gene)
SH2D2AGeneProduct9047 (Entrez Gene)
SH2D3CGeneProduct10044 (Entrez Gene)
SH3BP2GeneProduct6452 (Entrez Gene)
SHBGeneProduct6461 (Entrez Gene)
SHC1GeneProduct6464 (Entrez Gene)
SIT1GeneProduct27240 (Entrez Gene)
SLA2GeneProduct84174 (Entrez Gene)
SLAGeneProduct6503 (Entrez Gene)
SOS1GeneProduct6654 (Entrez Gene)
SOS2GeneProduct6655 (Entrez Gene)
SRCGeneProduct6714 (Entrez Gene)
STAT1GeneProduct6772 (Entrez Gene)
STAT5AGeneProduct6776 (Entrez Gene)
STAT5BGeneProduct6777 (Entrez Gene)
STK39GeneProduct27347 (Entrez Gene)
SYKGeneProduct6850 (Entrez Gene)
TRA@GeneProduct6955 (Entrez Gene)
TRAT1GeneProduct50852 (Entrez Gene)
TRB@GeneProduct6957 (Entrez Gene)
TUBA1GeneProduct7277 (Entrez Gene)
TUBBGeneProduct203068 (Entrez Gene)
TXKGeneProduct7294 (Entrez Gene)
UNC119GeneProduct9094 (Entrez Gene)
VASPGeneProduct7408 (Entrez Gene)
VAV1GeneProduct7409 (Entrez Gene)
VAV2GeneProduct7410 (Entrez Gene)
VAV3GeneProduct10451 (Entrez Gene)
WASGeneProduct7454 (Entrez Gene)
WASF2GeneProduct10163 (Entrez Gene)
WASPIPGeneProduct7456 (Entrez Gene)
YWHAQGeneProduct10971 (Entrez Gene)
ZAP70GeneProduct7535 (Entrez Gene)

Annotated Interactions

No annotated interactions
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