Kit receptor signaling pathway (Gallus gallus)

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EndosomeMolecular associationDemethylationEndoplasmic reticulumCYTranslocationERGOGolgi apparatusUbiquitinationMolecule in the pathwayGlycosylationMethylationDDeubiquitinationAcetylationSumoylationPlasma MembraneReceptorAccession Number: NetPath 6; cellmap:6Gene SymbolControlPMRecruitmentReaction through unknown mechanisms/moleculesp85 complexDesumoylationAutophosphorlation(Protein-protein interaction)Proteins in a complex interactionProteolytic cleavageNucleusCY->PMDeacetylationENECActivationPalmitoylationEnzyme complexCytoplasmDInhibitionNUPhosphorylationDephosphorylationMitochondrionLigandMTExtracellularMPDZMITFGRB2RCJMB04_5a10KITLGMATKSOS1EP300PTPN11FYNPTPRUCBLPTPN6GRB10INPP5DCBLBABL1SOCS1HRASRASA1SHC1SOCS5CISHDOK1MAPK1SH2B2STAT5ASPRED1VAV1CSF2RBFGRSH3KBP1SOCS4KITSTAT3CRKTRAILR1PIK3R1STAT5BSPRED2PLCE1HCKPRKCBCLTCTECDOK1RAF1KITAKT1BADGRAPLYNPIK3R2JAK2EPORSRCFESYES1PIK3CGBTKRCJMB04_17i9KITLGSOCS6GRB7STAP1VAV2MAP2K1CRKLPLCG1RPS6KA1


Description

No description

Comments

GenMAPP notes 
NetPath 6; cellmap:6 - Kit Receptor Signaling Pathway. The Kit Receptor signaling pathway was kindly reviewed by Imke Ehlers in Peter Besmer’s lab. This cancer signaling pathway is available at Cancer Cell Map (http://cancer.cellmap.org) and NetPath (http://www.netpath.org) and is part of a collaborative project between the Computational Biology Center at Memorial Sloan-Kettering Cancer Center (http://cbio.mskcc.org), PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the Cancer Cell Map and NetPath websites until the pathway is published.
GenMAPP remarks 
http://cancer.cellmap.org; http://www.netpath.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP304(r21319) with a 77% conversion rate.

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Bibliography

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History

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CompareRevisionActionTimeUserComment
117208view09:24, 19 May 2021EweitzModified title
68876view17:22, 8 July 2013MaintBotUpdated to 2013 gpml schema
67429view11:00, 26 June 2013DdiglesOntology Term : 'Stem Cell Factor signaling pathway' added !
41017view22:57, 1 March 2011MaintBotRemoved redundant pathway information and comments
35756view00:04, 13 February 2010AlexanderPico
33938view18:13, 9 December 2009MaintBotAutomatic update of empty xrefs
31508view21:35, 13 August 2009MaintBotFixed text labels
30343view20:50, 29 July 2009MaintBotNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
ABL1GeneProduct417181 (Entrez Gene)
AKT1GeneProduct395928 (Entrez Gene)
BADGeneProduct
BTKGeneProduct374075 (Entrez Gene)
CBLGeneProduct374038 (Entrez Gene)
CBLBGeneProduct418406 (Entrez Gene)
CISHGeneProduct395335 (Entrez Gene)
CLTCGeneProduct395272 (Entrez Gene)
CRKGeneProduct417553 (Entrez Gene)
CRKLGeneProduct416939 (Entrez Gene)
CSF2RBGeneProduct
DOK1GeneProduct
EP300GeneProduct418000 (Entrez Gene)
EPORGeneProduct
FESGeneProduct429374 (Entrez Gene)
FGRGeneProduct
FYNGeneProduct396294 (Entrez Gene)
GRAPGeneProduct416523 (Entrez Gene)
GRB10GeneProduct420948 (Entrez Gene)
GRB2GeneProduct386572 (Entrez Gene)
GRB7GeneProduct
HCKGeneProduct419280 (Entrez Gene)
HRASGeneProduct396229 (Entrez Gene)
INPP5DGeneProduct424745 (Entrez Gene)
JAK2GeneProduct374199 (Entrez Gene)
KITGeneProduct378783 (Entrez Gene)
KITLGGeneProduct396028 (Entrez Gene)
LYNGeneProduct421127 (Entrez Gene)
MAP2K1GeneProduct415549 (Entrez Gene)
MAPK1GeneProduct373953 (Entrez Gene)
MATKGeneProduct769076 (Entrez Gene)
MITFGeneProduct395886 (Entrez Gene)
MPDZGeneProduct
PIK3CGGeneProduct417706 (Entrez Gene)
PIK3R1GeneProduct427171 (Entrez Gene)
PIK3R2GeneProduct771142 (Entrez Gene)
PLCE1GeneProduct
PLCG1GeneProduct
PRKCBGeneProduct416567 (Entrez Gene)
PTPN11GeneProduct395815 (Entrez Gene)
PTPN6GeneProduct427947 (Entrez Gene)
PTPRUGeneProduct395153 (Entrez Gene)
RAF1GeneProduct396245 (Entrez Gene)
RASA1GeneProduct427327 (Entrez Gene)
RCJMB04_17i9GeneProduct424044 (Entrez Gene)
RCJMB04_5a10GeneProduct417430 (Entrez Gene)
RPS6KA1GeneProduct
SH2B2GeneProduct771172 (Entrez Gene)
SH3KBP1GeneProduct418608 (Entrez Gene)
SHC1GeneProduct
SOCS1GeneProduct416630 (Entrez Gene)
SOCS4GeneProduct423557 (Entrez Gene)
SOCS5GeneProduct428570 (Entrez Gene)
SOCS6GeneProduct421020 (Entrez Gene)
SOS1GeneProduct
SPRED1GeneProduct423292 (Entrez Gene)
SPRED2GeneProduct421271 (Entrez Gene)
SRCGeneProduct396442 (Entrez Gene)
STAP1GeneProduct428761 (Entrez Gene)
STAT3GeneProduct420027 (Entrez Gene)
STAT5AGeneProduct
STAT5BGeneProduct395556 (Entrez Gene)
TECGeneProduct396407 (Entrez Gene)
TRAILR1GeneProduct
VAV1GeneProduct
VAV2GeneProduct373938 (Entrez Gene)
YES1GeneProduct396238 (Entrez Gene)

Annotated Interactions

No annotated interactions
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