NOD pathway (Homo sapiens)

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Muramyl Dipeptidee.g. Bacillus anthracis Peptidoglycan InflammasomeActivated by Flagellin from L. pneumophila,S. typhimurium, Shigella flexneri, or P. aeruginosacleavesMuramyl Dipeptide &ATP induce Oligomerization CleavescleavesNigericin, Maitotoxin, Aerolysin(pore forming toxins)Asbestos, Silica Gram +ve L. monocytogenesS. aureus, M. marinum ATPcleavesCASP1NLRP2NLRC4HSP90AA2CASP8PYCARDNLRP4CARD9NLRP1IL18NDUFA13NOD1CARD6NLRP10RAC1NLRP7NLRP3NLRP12RIPK2CENTB1IL1BCASP9RELAIKBKGCARD8SUGT1IKBKBCOPS6CASP5NFKBIANAIPCHUKMEFVNOD2


Description

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Bibliography


History

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CompareRevisionActionTimeUserComment
33715view19:58, 7 December 2009MaintBotDeleted pathway: Duplicate: http://www.wikipathways.org/index.php/Pathway:WP1433
33005view23:39, 30 September 2009MisbahPeriodical save, work in progress
33004view23:02, 30 September 2009MisbahPeriodical save, work in progress
33003view22:34, 30 September 2009MisbahUPDATES
33002view22:30, 30 September 2009MisbahPeriodical save, work in progress
33001view21:40, 30 September 2009MisbahPeriodical save, work in progress
33000view21:04, 30 September 2009MisbahPeriodical save, work in progress
32999view19:34, 30 September 2009MisbahPeriodical save, work in progress
32998view19:24, 30 September 2009MisbahPeriodical save, work in progress
32994view19:00, 30 September 2009MisbahPeriodical save, work in progress
32991view18:43, 30 September 2009MisbahPeriodical save, work in progress
32989view18:33, 30 September 2009MisbahPeriodical save, work in progress
32987view17:48, 30 September 2009MisbahNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
CARD6GeneProductENSG00000132357 (Ensembl Human)
CARD8GeneProductENSG00000105483 (Ensembl Human)
CARD9GeneProductENSG00000187796 (Ensembl Human)
CASP1GeneProductENSG00000137752 (Ensembl Human)
CASP5GeneProductENSG00000137757 (Ensembl Human)
CASP8GeneProductENSG00000064012 (Ensembl Human)
CASP9GeneProductENSG00000132906 (Ensembl Human)
CENTB1GeneProductENSG00000072818 (Ensembl Human)
CHUKGeneProductENSG00000213341 (Ensembl Human)
COPS6GeneProductENSG00000168090 (Ensembl Human)
HSP90AA2GeneProductENSG00000080824 (Ensembl Human)
IKBKBGeneProductENSG00000104365 (Ensembl Human)
IKBKGGeneProductENSG00000073009 (Ensembl Human)
IL18GeneProductENSG00000150782 (Ensembl Human)
IL1BGeneProductENSG00000125538 (Ensembl Human)
MEFVGeneProductENSG00000103313 (Ensembl Human)
NAIPGeneProductENSG00000081770 (Ensembl Human)
NDUFA13GeneProductENSG00000130288 (Ensembl Human)
NFKBIAGeneProductENSG00000100906 (Ensembl Human)
NLRC4GeneProductENSG00000091106 (Ensembl Human)
NLRP10GeneProductENSG00000182261 (Ensembl Human)
NLRP12GeneProductENSG00000142405 (Ensembl Human)
NLRP1GeneProductENSG00000091592 (Ensembl Human)
NLRP2GeneProductENSG00000022556 (Ensembl Human)
NLRP3GeneProductENSG00000162711 (Ensembl Human)
NLRP4GeneProductENSG00000160505 (Ensembl Human)
NLRP7GeneProductENSG00000167634 (Ensembl Human)
NOD1GeneProductENSG00000106100 (Ensembl Human)
NOD2GeneProductENSG00000167207 (Ensembl Human)
PYCARDGeneProductENSG00000103490 (Ensembl Human)
RAC1GeneProductENSG00000136238 (Ensembl Human)
RELAGeneProductENSG00000173039 (Ensembl Human)
RIPK2GeneProductENSG00000104312 (Ensembl Human)
SUGT1GeneProductENSG00000165416 (Ensembl Human)

Annotated Interactions

No annotated interactions

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