NOD pathway (Homo sapiens)

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CleavescleavesMuramyl Dipeptide &ATP induce Oligomerization Activated by Flagellin from L. pneumophila,S. typhimurium, Shigella flexneri, or P. aeruginosaInflammasomeMuramyl Dipeptidee.g. Bacillus anthracis Nigericin, Maitotoxin, Aerolysin(pore forming toxins)Asbestos, Silica Gram +ve L. monocytogenesS. aureus, M. marinum ATPPeptidoglycan cleavescleavesdownregulatesUpregulatesNLRP7RELANFKBIANOD2IL18CARD6NLRP12IKBKBPRDM1MEFVRAC1NDUFA13CENTB1IKBKGNLRP10CASP1NLRC4NOD1CASP8NLRP3HSP90AA2CHUKNLRP1CARD9DUOX2NLRP2IL1BCARD8NLRP4CASP9RIPK2PYCARDNAIPSUGT1CASP5COPS6AAMPXIAP


Description

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Quality Tags

Ontology Terms

 

Bibliography


History

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CompareRevisionActionTimeUserComment
33715view19:58, 7 December 2009MaintBotDeleted pathway: Duplicate: http://www.wikipathways.org/index.php/Pathway:WP1433
33005view23:39, 30 September 2009MisbahPeriodical save, work in progress
33004view23:02, 30 September 2009MisbahPeriodical save, work in progress
33003view22:34, 30 September 2009MisbahUPDATES
33002view22:30, 30 September 2009MisbahPeriodical save, work in progress
33001view21:40, 30 September 2009MisbahPeriodical save, work in progress
33000view21:04, 30 September 2009MisbahPeriodical save, work in progress
32999view19:34, 30 September 2009MisbahPeriodical save, work in progress
32998view19:24, 30 September 2009MisbahPeriodical save, work in progress
32994view19:00, 30 September 2009MisbahPeriodical save, work in progress
32991view18:43, 30 September 2009MisbahPeriodical save, work in progress
32989view18:33, 30 September 2009MisbahPeriodical save, work in progress
32987view17:48, 30 September 2009MisbahNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
AAMPGeneProductENSG00000127837 (Ensembl Human)
CARD6GeneProductENSG00000132357 (Ensembl Human)
CARD8GeneProductENSG00000105483 (Ensembl Human)
CARD9GeneProductENSG00000187796 (Ensembl Human)
CASP1GeneProductENSG00000137752 (Ensembl Human)
CASP5GeneProductENSG00000137757 (Ensembl Human)
CASP8GeneProductENSG00000064012 (Ensembl Human)
CASP9GeneProductENSG00000132906 (Ensembl Human)
CENTB1GeneProductENSG00000072818 (Ensembl Human)
CHUKGeneProductENSG00000213341 (Ensembl Human)
COPS6GeneProductENSG00000168090 (Ensembl Human)
DUOX2GeneProductENSG00000140279 (Ensembl Human)
HSP90AA2GeneProductENSG00000080824 (Ensembl Human)
IKBKBGeneProductENSG00000104365 (Ensembl Human)
IKBKGGeneProductENSG00000073009 (Ensembl Human)
IL18GeneProductENSG00000150782 (Ensembl Human)
IL1BGeneProductENSG00000125538 (Ensembl Human)
MEFVGeneProductENSG00000103313 (Ensembl Human)
NAIPGeneProductENSG00000081770 (Ensembl Human)
NDUFA13GeneProductENSG00000130288 (Ensembl Human)
NFKBIAGeneProductENSG00000100906 (Ensembl Human)
NLRC4GeneProductENSG00000091106 (Ensembl Human)
NLRP10GeneProductENSG00000182261 (Ensembl Human)
NLRP12GeneProductENSG00000142405 (Ensembl Human)
NLRP1GeneProductENSG00000091592 (Ensembl Human)
NLRP2GeneProductENSG00000022556 (Ensembl Human)
NLRP3GeneProductENSG00000162711 (Ensembl Human)
NLRP4GeneProductENSG00000160505 (Ensembl Human)
NLRP7GeneProductENSG00000167634 (Ensembl Human)
NOD1GeneProductENSG00000106100 (Ensembl Human)
NOD2GeneProductENSG00000167207 (Ensembl Human)
PRDM1GeneProductENSG00000057657 (Ensembl Human)
PYCARDGeneProductENSG00000103490 (Ensembl Human)
RAC1GeneProductENSG00000136238 (Ensembl Human)
RELAGeneProductENSG00000173039 (Ensembl Human)
RIPK2GeneProductENSG00000104312 (Ensembl Human)
SUGT1GeneProductENSG00000165416 (Ensembl Human)
XIAPGeneProductENSG00000101966 (Ensembl Human)

Annotated Interactions

No annotated interactions

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