Regulation of actin cytoskeleton (Gallus gallus)

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Actin polymerizationPI3KGPCR+pGene ExpressionRTKFocal complexassembly?Stabilizationof actinRASPI3KAdherens junction pathwayGFGrowth Factor (GF)MAPK SignalingpathwayRTKChemotactic factorGPCR-pFocal adhesionassemblyLamellipodiaActomyosinassembly contractionFocal adhesion pathwayActin polymerizationstress fiberFilipodiaRASActin polymerizationstress fiberChemotatic factorFocal adhesion pathwayFGFR4PIP5K1CMAP2K2WASCHRM5CSKNRASFGFR1PFN1LOC442775TPTERCJMB04_22k13TPTEFGF4TPTEFGF9MRASFGF20PIP2ARHGEF1PDGFBMSNGNA13TMSB4XMYL3PIK3CGPAK4EGFRAC1P4RDXIQGAP1MYL1MAPK1CHRM3FGF14PIK3C2APIP5K1ARHOAFGF23TPTERCJMB04_4h19FGF1FGF11LIMK1C11orf13SSH3ARHGEF6PIP4K2ARAC3PIK3CBFGF16VCLPIK3R5CDC42ARPC5ARPC5MAP2K1CRKBradykininPIK3R3APCFGF12Apc2TPTESLC9A1PXNABI2PIK3C2GPIK3R1MYH10ARHGEF7MAPK4FGF2CHRM2RRASTPTEPIP4K2APIP3DOCK1RCJMB04_5i17BAIAP2ROCK1PAK7FGF17SSH1NCKAP1PIK3CDFGF18FGFR2F2RFGF8PTK2FGF7LOC426359PAK1CYFIP2FN1EZRBDKRB1MYLKGRLF1FGF6ITGA1PIP2GNG12PDGFRAGSNFGF22PIK3R2SOS2RCJMB04_1h13KRASPik3c2bRCJMB04_23c5FGF21CHRM1PDGFRBMAPK3FGF5BRAFPDGFASOS1SSH2PFN1AcetylcholinePIK3C3FGD1EGFRRCJMB04_4h19CHRM4GNA12BAIAP2PAK2F2VIL1RCJMB04_4h19RAC2RAF1PAK3RAC1RCJMB04_20j15ARHGEF4PIP5K2CGIT1BDKRB2LPSMOSWASF1FGF13CFL1BCAR1CFL2FGF10PIP5KL1RRAS2ARHGEF6FGF3FGFR3PAK6VCLCD14RCJMB04_1h13PIK3R4PIK3CAVAV1RCJMB04_1h13ROCK2PIP4K2BENAH


Description

No description

Comments

GenMAPP notes 
http://www.genome.jp/kegg/pathway/hsa/hsa04810.html
GenMAPP remarks 
Adapted from KEGG (right-click to see notes)
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP51(r20783) with a 76% conversion rate.

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Ontology Terms

 

Bibliography

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History

View all...
CompareRevisionActionTimeUserComment
117210view09:26, 19 May 2021EweitzModified title
109469view10:59, 18 March 2020L DupuisConverted interaction lines to graphical lines where applicable
72069view17:52, 24 October 2013MaintBotUpdated data sources
68796view17:14, 8 July 2013MaintBotUpdated to 2013 gpml schema
67625view11:35, 26 June 2013DdiglesOntology Term : 'cell adhesion signaling pathway' added !
47796view16:38, 6 April 2012Khanspersupdated xrefs
40928view22:51, 1 March 2011MaintBotRemoved redundant pathway information and comments
33859view17:45, 9 December 2009MaintBotAutomatic update of empty xrefs
33495view15:12, 30 November 2009MaintBotRemoved group label
31542view21:49, 13 August 2009MaintBotFixed text labels
30393view21:07, 29 July 2009MaintBotNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
ABI2GeneProduct424108 (Entrez Gene)
APCGeneProduct415607 (Entrez Gene)
ARHGEF1GeneProduct
ARHGEF4GeneProduct424761 (Entrez Gene)
ARHGEF6GeneProduct422247 (Entrez Gene)
ARHGEF7GeneProduct418761 (Entrez Gene)
ARPC5GeneProduct429075 (Entrez Gene)
AcetylcholineGeneProduct
Apc2GeneProduct
BAIAP2GeneProduct422077 (Entrez Gene)
BCAR1GeneProduct415691 (Entrez Gene)
BDKRB1GeneProduct772372 (Entrez Gene)
BDKRB2GeneProduct428906 (Entrez Gene)
BRAFGeneProduct396239 (Entrez Gene)
BradykininGeneProduct
C11orf13GeneProduct
CD14GeneProduct
CDC42GeneProduct395917 (Entrez Gene)
CFL1GeneProduct
CFL2GeneProduct423320 (Entrez Gene)
CHRM1GeneProduct
CHRM2GeneProduct418126 (Entrez Gene)
CHRM3GeneProduct396364 (Entrez Gene)
CHRM4GeneProduct423195 (Entrez Gene)
CHRM5GeneProduct428881 (Entrez Gene)
CRKGeneProduct417553 (Entrez Gene)
CSKGeneProduct396396 (Entrez Gene)
CYFIP2GeneProduct416246 (Entrez Gene)
DOCK1GeneProduct423960 (Entrez Gene)
EGFGeneProduct408035 (Entrez Gene)
EGFRGeneProduct
ENAHGeneProduct
EZRGeneProduct395701 (Entrez Gene)
F2GeneProduct395306 (Entrez Gene)
F2RGeneProduct427212 (Entrez Gene)
FGD1GeneProduct
FGF10GeneProduct
FGF11GeneProduct
FGF12GeneProduct395704 (Entrez Gene)
FGF13GeneProduct414831 (Entrez Gene)
FGF1GeneProduct396094 (Entrez Gene)
FGF14GeneProduct395554 (Entrez Gene)
FGF16GeneProduct422330 (Entrez Gene)
FGF17GeneProduct
FGF18GeneProduct395453 (Entrez Gene)
FGF20GeneProduct428779 (Entrez Gene)
FGF21GeneProduct
FGF22GeneProduct
FGF23GeneProduct428104 (Entrez Gene)
FGF2GeneProduct396413 (Entrez Gene)
FGF3GeneProduct396267 (Entrez Gene)
FGF4GeneProduct428857 (Entrez Gene)
FGF5GeneProduct770457 (Entrez Gene)
FGF6GeneProduct768907 (Entrez Gene)
FGF7GeneProduct415439 (Entrez Gene)
FGF8GeneProduct396313 (Entrez Gene)
FGF9GeneProduct378917 (Entrez Gene)
FGFR1GeneProduct396516 (Entrez Gene)
FGFR2GeneProduct396259 (Entrez Gene)
FGFR3GeneProduct396515 (Entrez Gene)
FGFR4GeneProduct
FN1GeneProduct396133 (Entrez Gene)
GIT1GeneProduct
GNA12GeneProduct769924 (Entrez Gene)
GNA13GeneProduct417434 (Entrez Gene)
GNG12GeneProduct772239 (Entrez Gene)
GRLF1GeneProduct
GSNGeneProduct395774 (Entrez Gene)
IQGAP1GeneProduct415591 (Entrez Gene)
ITGA1GeneProduct395951 (Entrez Gene)
KRASGeneProduct418207 (Entrez Gene)
LIMK1GeneProduct373922 (Entrez Gene)
LOC426359GeneProduct426359 (Entrez Gene)
LOC442775GeneProduct
LPSMetaboliteC00338 (Kegg Compound)
MAP2K1GeneProduct415549 (Entrez Gene)
MAP2K2GeneProduct396349 (Entrez Gene)
MAPK1GeneProduct373953 (Entrez Gene)
MAPK3GeneProduct
MAPK4GeneProduct
MOSGeneProduct428537 (Entrez Gene)
MRASGeneProduct395149 (Entrez Gene)
MSNGeneProduct
MYH10GeneProduct396465 (Entrez Gene)
MYL1GeneProduct396470 (Entrez Gene)
MYL3GeneProduct396067 (Entrez Gene)
MYLKGeneProduct396445 (Entrez Gene)
NCKAP1GeneProduct424000 (Entrez Gene)
NRASGeneProduct419885 (Entrez Gene)
PAK1GeneProduct419083 (Entrez Gene)
PAK2GeneProduct424860 (Entrez Gene)
PAK3GeneProduct422342 (Entrez Gene)
PAK4GeneProduct770462 (Entrez Gene)
PAK6GeneProduct428837 (Entrez Gene)
PAK7GeneProduct416734 (Entrez Gene)
PDGFAGeneProduct374196 (Entrez Gene)
PDGFBGeneProduct374128 (Entrez Gene)
PDGFRAGeneProduct395509 (Entrez Gene)
PDGFRBGeneProduct770488 (Entrez Gene)
PFN1GeneProduct
PIK3C2AGeneProduct423070 (Entrez Gene)
PIK3C2GGeneProduct418181 (Entrez Gene)
PIK3C3GeneProduct
PIK3CAGeneProduct424971 (Entrez Gene)
PIK3CBGeneProduct424826 (Entrez Gene)
PIK3CDGeneProduct419444 (Entrez Gene)
PIK3CGGeneProduct417706 (Entrez Gene)
PIK3R1GeneProduct427171 (Entrez Gene)
PIK3R2GeneProduct771142 (Entrez Gene)
PIK3R3GeneProduct
PIK3R4GeneProduct428449 (Entrez Gene)
PIK3R5GeneProduct417319 (Entrez Gene)
PIP2MetaboliteC04637 (Kegg Compound)
PIP3MetaboliteC05981 (Kegg Compound)
PIP4K2AGeneProduct420504 (Entrez Gene)
PIP4K2BGeneProduct419999 (Entrez Gene)
PIP5K1AGeneProduct
PIP5K1CGeneProduct420072 (Entrez Gene)
PIP5K2CGeneProduct
PIP5KL1GeneProduct
PTK2GeneProduct396416 (Entrez Gene)
PXNGeneProduct395832 (Entrez Gene)
Pik3c2bGeneProduct
RAC1GeneProduct395871 (Entrez Gene)
RAC1P4GeneProduct
RAC2GeneProduct418044 (Entrez Gene)
RAC3GeneProduct395870 (Entrez Gene)
RAF1GeneProduct396245 (Entrez Gene)
RCJMB04_1h13GeneProduct415296 (Entrez Gene)
RCJMB04_20j15GeneProduct427243 (Entrez Gene)
RCJMB04_22k13GeneProduct396020 (Entrez Gene)
RCJMB04_23c5GeneProduct373918 (Entrez Gene)
RCJMB04_4h19GeneProduct396526 (Entrez Gene)
RCJMB04_5i17GeneProduct415419 (Entrez Gene)
RDXGeneProduct395511 (Entrez Gene)
RHOAGeneProduct395442 (Entrez Gene)
ROCK1GeneProduct373970 (Entrez Gene)
ROCK2GeneProduct374182 (Entrez Gene)
RRASGeneProduct
RRAS2GeneProduct423062 (Entrez Gene)
SLC9A1GeneProduct419580 (Entrez Gene)
SOS1GeneProduct
SOS2GeneProduct423572 (Entrez Gene)
SSH1GeneProduct427699 (Entrez Gene)
SSH2GeneProduct417586 (Entrez Gene)
SSH3GeneProduct
TMSB4XGeneProduct
TPTEGeneProduct418885 (Entrez Gene)
VAV1GeneProduct
VCLGeneProduct396422 (Entrez Gene)
VIL1GeneProduct396423 (Entrez Gene)
WASGeneProduct
WASF1GeneProduct421761 (Entrez Gene)

Annotated Interactions

No annotated interactions
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