Insulin Signaling (Pan troglodytes)

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1Transcriptional Regulators & Immediate Early GenesPI 3-KinaseTranslation RegulationMetabolic RegulationInsulin Receptor SubstratesTor Signalingp70 S6 KinasesPDK/Akt SignalingRas-MAPK SignalingGlucose TransportVesicular TraffickingMEK/MAP Kinasesp90 Rsk KinasesModulators of Insulin ActionSHC3IGF1RINSRMAP2K6MAP3K13FOSPIK3C2ARPS6KA4MAP3K1MAP4K2KIF5BMAP2K7FRAP1GSK3AEHD2RAC1PFKMRRADIRS1HRASMAPK12GAB1PRKAA1PTENSTXBP3RPS6KA2MAP3K11MAPK4MAP3K7ARF1SH2B2MAP3K12EGR1GYS1MAP3K5EHD1GYG1RPS6KB1PIK3C2GTSC1MAPK1IRS4MAP4K3FOXO3ATSC2MAPK14SNX26MAP3K2PRKAA2RAB4ASGKPIK3R3MAP2K3MAP2K5SLC2A4EIF4EBP1SHC1STXBP4PSCD3PRKCHEIF4EKIF3AMAPK9PIK3R2RPS6KA5PDPK1MAPK3PTPN1CAP1PIK3CDPIK3R4MAP3K6SOS2SRFRPS6KA3MAP3K4STX4APFKLSGK2VAMP2PIK3CBMAPK8INPPL1RAPGEF1ARF6SOS1PRKCDMAP2K2RHOXF2STXBP1MYO1CGRB14MAP4K4PTPRFCBLBFLOT1MAP3K9SNAP25MAP2K1MAP4K1MAPK11INPP4ARHOQPIK3R1ELK1MAP2K4PRKCAPIK3C3GSK3BXBP1JUNMINK1SLC2A1PTPN11IKBKBCRKPIK3CGIRS2TBC1D4MAP3K14GRB2MAPK13MAPK10SNAP23TRIB3PRKCB1PRKCQRAC2CBLMAP4K5RPS6KB2AKT1SORBS1CBLCPRKCIMAP3K8GRB10MAPK7MAPK6PRKCZRAF1FOXO1GYS2SOCS3SGK3FLOT2SHC2RPS6KA6PPP1R3AMAPK8RHEBRPS6KA1PIK3CARHOJAKT2MAP3K3LIPESTXBP2ENPP1SOCS1MAP3K10


Description

No description

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP481(r28132) with a 72% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Bevan P; ''Insulin signalling.''; J Cell Sci, 2001 PubMed Europe PMC Scholia
  2. Quon MJ, Campfield LA; ''A mathematical model and computer simulation study of insulin sensitive glucose transporter regulation.''; J Theor Biol, 1991 PubMed Europe PMC Scholia
  3. Saltiel AR, Kahn CR; ''Insulin signalling and the regulation of glucose and lipid metabolism.''; Nature, 2001 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
69319view18:44, 8 July 2013MaintBotUpdated to 2013 gpml schema
48148view18:41, 9 May 2012MaintBotUpdating from human to fix xrefs
41629view02:03, 2 March 2011MaintBotRemoved redundant pathway information and comments
34356view22:24, 9 December 2009MaintBotAutomatic update of empty xrefs
33517view15:19, 30 November 2009MaintBotRemoved group label
31557view21:54, 13 August 2009MaintBotFixed text labels
30416view21:15, 29 July 2009MaintBotNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
AKT1GeneProduct740898 (Entrez Gene)
AKT2GeneProduct456035 (Entrez Gene)
ARF1GeneProduct
ARF6GeneProduct452892 (Entrez Gene)
CAP1GeneProduct746432 (Entrez Gene)
CBLGeneProduct451690 (Entrez Gene)
CBLBGeneProduct460566 (Entrez Gene)
CBLCGeneProduct
CRKGeneProduct747142 (Entrez Gene)
EGR1GeneProduct462097 (Entrez Gene)
EHD1GeneProduct744047 (Entrez Gene)
EHD2GeneProduct456170 (Entrez Gene)
EIF4EGeneProduct
EIF4EBP1GeneProduct464114 (Entrez Gene)
ELK1GeneProduct
ENPP1GeneProduct463002 (Entrez Gene)
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FLOT2GeneProduct454537 (Entrez Gene)
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FOXO1GeneProduct467352 (Entrez Gene)
FOXO3AGeneProduct
FRAP1GeneProduct
GAB1GeneProduct461516 (Entrez Gene)
GRB10GeneProduct463410 (Entrez Gene)
GRB14GeneProduct459695 (Entrez Gene)
GRB2GeneProduct737245 (Entrez Gene)
GSK3AGeneProduct456071 (Entrez Gene)
GSK3BGeneProduct470896 (Entrez Gene)
GYG1GeneProduct460765 (Entrez Gene)
GYS1GeneProduct
GYS2GeneProduct465336 (Entrez Gene)
HRASGeneProduct466302 (Entrez Gene)
IGF1RGeneProduct453676 (Entrez Gene)
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INPP4AGeneProduct470448 (Entrez Gene)
INPPL1GeneProduct451403 (Entrez Gene)
INSRGeneProduct
IRS1GeneProduct459985 (Entrez Gene)
IRS2GeneProduct452657 (Entrez Gene)
IRS4GeneProduct
JUNGeneProduct456893 (Entrez Gene)
KIF3AGeneProduct450168 (Entrez Gene)
KIF5BGeneProduct450390 (Entrez Gene)
LIPEGeneProduct
MAP2K1GeneProduct450188 (Entrez Gene)
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MAP3K1GeneProduct
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MAP4K1GeneProduct
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MAPK4GeneProduct
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MINK1GeneProduct454455 (Entrez Gene)
MYO1CGeneProduct750403 (Entrez Gene)
PDPK1GeneProduct
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PIK3C2AGeneProduct451052 (Entrez Gene)
PIK3C2GGeneProduct
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PIK3CAGeneProduct460858 (Entrez Gene)
PIK3CBGeneProduct
PIK3CDGeneProduct457922 (Entrez Gene)
PIK3CGGeneProduct463649 (Entrez Gene)
PIK3R1GeneProduct461836 (Entrez Gene)
PIK3R2GeneProduct455855 (Entrez Gene)
PIK3R3GeneProduct
PIK3R4GeneProduct460692 (Entrez Gene)
PPP1R3AGeneProduct463666 (Entrez Gene)
PRKAA1GeneProduct
PRKAA2GeneProduct741802 (Entrez Gene)
PRKCAGeneProduct
PRKCB1GeneProduct
PRKCDGeneProduct
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PRKCIGeneProduct450143 (Entrez Gene)
PRKCQGeneProduct450288 (Entrez Gene)
PRKCZGeneProduct743533 (Entrez Gene)
PSCD3GeneProduct
PTENGeneProduct466142 (Entrez Gene)
PTPN11GeneProduct
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PTPRFGeneProduct456828 (Entrez Gene)
RAB4AGeneProduct
RAC1GeneProduct
RAC2GeneProduct742575 (Entrez Gene)
RAF1GeneProduct460182 (Entrez Gene)
RAPGEF1GeneProduct464812 (Entrez Gene)
RHEBGeneProduct463880 (Entrez Gene)
RHOJGeneProduct452960 (Entrez Gene)
RHOQGeneProduct740809 (Entrez Gene)
RHOXF2GeneProduct473763 (Entrez Gene)
RPS6KA1GeneProduct
RPS6KA2GeneProduct
RPS6KA3GeneProduct
RPS6KA4GeneProduct451715 (Entrez Gene)
RPS6KA5GeneProduct739162 (Entrez Gene)
RPS6KA6GeneProduct
RPS6KB1GeneProduct468426 (Entrez Gene)
RPS6KB2GeneProduct746903 (Entrez Gene)
RRADGeneProduct741038 (Entrez Gene)
SGKGeneProduct
SGK2GeneProduct740699 (Entrez Gene)
SGK3GeneProduct464217 (Entrez Gene)
SH2B2GeneProduct741557 (Entrez Gene)
SHC1GeneProduct457351 (Entrez Gene)
SHC2GeneProduct
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SLC2A1GeneProduct
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SNAP23GeneProduct453365 (Entrez Gene)
SNAP25GeneProduct458096 (Entrez Gene)
SNX26GeneProduct
SOCS1GeneProduct737070 (Entrez Gene)
SOCS3GeneProduct454921 (Entrez Gene)
SORBS1GeneProduct450628 (Entrez Gene)
SOS1GeneProduct459171 (Entrez Gene)
SOS2GeneProduct
SRFGeneProduct462709 (Entrez Gene)
STX4AGeneProduct
STXBP1GeneProduct
STXBP2GeneProduct741963 (Entrez Gene)
STXBP3GeneProduct737947 (Entrez Gene)
STXBP4GeneProduct468411 (Entrez Gene)
TBC1D4GeneProduct467286 (Entrez Gene)
TRIB3GeneProduct
TSC1GeneProduct464818 (Entrez Gene)
TSC2GeneProduct468086 (Entrez Gene)
VAMP2GeneProduct747237 (Entrez Gene)
XBP1GeneProduct458735 (Entrez Gene)

Annotated Interactions

No annotated interactions
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