Regulation of actin cytoskeleton (Pan troglodytes)

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Growth Factor (GF)Stabilizationof actinChemotatic factorGPCRActin polymerizationstress fiberFilipodiaGFFocal adhesion pathwayMAPK SignalingpathwayLamellipodiaPI3KPI3KRTKGPCRRTKActin polymerizationRASActin polymerization+p?-pFocal complexassemblyAdherens junction pathwayFocal adhesion pathwayGene ExpressionChemotactic factorRASActomyosinassembly contractionFocal adhesionassemblystress fiberPDGFRAPFN1MAPK3ARPC5ROCK2VAV1RASSF7FGFR3PIP4K2CCHRM4ACTBMYLKBradykininFGF5RHOXF2FGF20NRASPDGFBBAIAP2FGF6PIP5K1AARHGEF6VIL2CFL2PIK3R2PAK6FGF1RHOXF2SLC9A1ARHGEF1CFL1CHRM1BDKRB2FGF16Pik3c2bPIP5K1BROCK1FGF8FGF14RHOAFGF2FGF22MYL1RHOXF2SSH2ARHGEF7LIMK1RAC2PIK3CDPDGFAACTN1MRASEGFRITGA1IQGAP1ACTBNCKAP1MAPK1PTK2AcetylcholineRAF1Apc2FGF17PAK1RHOXF2PIP4K2ALOC442775RHOXF2PIK3C3PIK3R3PIK3R5APCMAPK6FGF3CHRM3RRAS2ACTBMSNPIP2CHRM2DOCK1ARPC5GRLF1PFN1FGF23RAC1P4WASF1PIK3CGFGF10FGFR4F2FGF13MOSFGF12BAIAP2PAK2RHOXF2GNA12GIT1CHRM5PIP4K2ARAC1FGF11F2RPIP2FGD1PDGFRBMYH10FGF7PIK3R1RRASACTG1PIK3R4PIK3C2GPPP1R12AFGFR1GNG12SOS2MAPK4FGF9MAP2K2ARHGEF4GNA13SSH1WASF2LPSPIK3CACDC42ACTG1ABI2SOS1ENAHPAK3FN1PXNACTG1CD14BRAFPAK4RAC3PIP4K2BCYFIP2PIP5KL1RDXBDKRB1PIP3MAP2K1TMSB4XFGF18MYL3CRKVCLFGF21VCLKRASCSKFGF4FGFR2PAK7GSNEGFVIL1PIK3C2APIK3CBBCAR1SSH3ARHGEF6PIP5K1CWAS


Description

No description

Comments

GenMAPP notes 
http://www.genome.jp/kegg/pathway/hsa/hsa04810.html
GenMAPP remarks 
Adapted from KEGG (right-click to see notes)
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP51(r20783) with a 74% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

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History

View all...
CompareRevisionActionTimeUserComment
128551view04:35, 12 February 2024EweitzModified title
114262view13:59, 2 January 2021EgonwThree more pathways clickable
72131view07:57, 25 October 2013Mkutmonadded datasource to pathway datanodes
71673view19:41, 17 October 2013MaintBotAutomated update of data sources
69266view18:38, 8 July 2013MaintBotUpdated to 2013 gpml schema
48143view18:34, 9 May 2012MaintBotUpdating from human to fix xrefs
41574view02:00, 2 March 2011MaintBotRemoved redundant pathway information and comments
34302view22:05, 9 December 2009MaintBotAutomatic update of empty xrefs
33594view09:54, 1 December 2009MaintBotRemoved group label
31614view22:15, 13 August 2009MaintBotFixed text labels
30513view21:46, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ABI2GeneProduct459892 (Entrez Gene)
ACTBGeneProduct450133 (Entrez Gene)
ACTG1GeneProduct
ACTN1GeneProduct452993 (Entrez Gene)
APCGeneProduct461999 (Entrez Gene)
ARHGEF1GeneProduct
ARHGEF4GeneProduct470538 (Entrez Gene)
ARHGEF6GeneProduct
ARHGEF7GeneProduct452673 (Entrez Gene)
ARPC5GeneProduct457574 (Entrez Gene)
AcetylcholineGeneProduct
Apc2GeneProduct
BAIAP2GeneProduct454951 (Entrez Gene)
BCAR1GeneProduct454246 (Entrez Gene)
BDKRB1GeneProduct
BDKRB2GeneProduct467547 (Entrez Gene)
BRAFGeneProduct463781 (Entrez Gene)
BradykininGeneProduct
CD14GeneProduct462118 (Entrez Gene)
CDC42GeneProduct456609 (Entrez Gene)
CFL1GeneProduct745772 (Entrez Gene)
CFL2GeneProduct452853 (Entrez Gene)
CHRM1GeneProduct451272 (Entrez Gene)
CHRM2GeneProduct463758 (Entrez Gene)
CHRM3GeneProduct469725 (Entrez Gene)
CHRM4GeneProduct
CHRM5GeneProduct503515 (Entrez Gene)
CRKGeneProduct747142 (Entrez Gene)
CSKGeneProduct453745 (Entrez Gene)
CYFIP2GeneProduct462221 (Entrez Gene)
DOCK1GeneProduct
EGFGeneProduct461435 (Entrez Gene)
EGFRGeneProduct463415 (Entrez Gene)
ENAHGeneProduct
F2GeneProduct451158 (Entrez Gene)
F2RGeneProduct471510 (Entrez Gene)
FGD1GeneProduct
FGF10GeneProduct471553 (Entrez Gene)
FGF11GeneProduct748965 (Entrez Gene)
FGF12GeneProduct471041 (Entrez Gene)
FGF13GeneProduct465886 (Entrez Gene)
FGF1GeneProduct462158 (Entrez Gene)
FGF14GeneProduct739338 (Entrez Gene)
FGF16GeneProduct473676 (Entrez Gene)
FGF17GeneProduct472708 (Entrez Gene)
FGF18GeneProduct739611 (Entrez Gene)
FGF2GeneProduct
FGF20GeneProduct739665 (Entrez Gene)
FGF21GeneProduct468948 (Entrez Gene)
FGF22GeneProduct468631 (Entrez Gene)
FGF23GeneProduct747164 (Entrez Gene)
FGF3GeneProduct466693 (Entrez Gene)
FGF4GeneProduct747727 (Entrez Gene)
FGF5GeneProduct471190 (Entrez Gene)
FGF6GeneProduct747181 (Entrez Gene)
FGF7GeneProduct744975 (Entrez Gene)
FGF8GeneProduct745174 (Entrez Gene)
FGF9GeneProduct744731 (Entrez Gene)
FGFR1GeneProduct464122 (Entrez Gene)
FGFR2GeneProduct466220 (Entrez Gene)
FGFR3GeneProduct
FGFR4GeneProduct462301 (Entrez Gene)
FN1GeneProduct459926 (Entrez Gene)
GIT1GeneProduct454549 (Entrez Gene)
GNA12GeneProduct463234 (Entrez Gene)
GNA13GeneProduct454827 (Entrez Gene)
GNG12GeneProduct
GRLF1GeneProduct
GSNGeneProduct464706 (Entrez Gene)
IQGAP1GeneProduct467762 (Entrez Gene)
ITGA1GeneProduct461880 (Entrez Gene)
KRASGeneProduct473387 (Entrez Gene)
LIMK1GeneProduct463466 (Entrez Gene)
LOC442775GeneProduct
LPSMetaboliteC00338 (Kegg Compound)
MAP2K1GeneProduct450188 (Entrez Gene)
MAP2K2GeneProduct456390 (Entrez Gene)
MAPK1GeneProduct458680 (Entrez Gene)
MAPK3GeneProduct454037 (Entrez Gene)
MAPK4GeneProduct
MAPK6GeneProduct453439 (Entrez Gene)
MOSGeneProduct472772 (Entrez Gene)
MRASGeneProduct
MSNGeneProduct
MYH10GeneProduct455090 (Entrez Gene)
MYL1GeneProduct459915 (Entrez Gene)
MYL3GeneProduct
MYLKGeneProduct460640 (Entrez Gene)
NCKAP1GeneProduct459801 (Entrez Gene)
NRASGeneProduct742713 (Entrez Gene)
PAK1GeneProduct451439 (Entrez Gene)
PAK2GeneProduct460965 (Entrez Gene)
PAK3GeneProduct450118 (Entrez Gene)
PAK4GeneProduct
PAK6GeneProduct
PAK7GeneProduct469876 (Entrez Gene)
PDGFAGeneProduct
PDGFBGeneProduct458844 (Entrez Gene)
PDGFRAGeneProduct
PDGFRBGeneProduct462188 (Entrez Gene)
PFN1GeneProduct
PIK3C2AGeneProduct451052 (Entrez Gene)
PIK3C2GGeneProduct
PIK3C3GeneProduct455385 (Entrez Gene)
PIK3CAGeneProduct460858 (Entrez Gene)
PIK3CBGeneProduct
PIK3CDGeneProduct457922 (Entrez Gene)
PIK3CGGeneProduct463649 (Entrez Gene)
PIK3R1GeneProduct461836 (Entrez Gene)
PIK3R2GeneProduct455855 (Entrez Gene)
PIK3R3GeneProduct
PIK3R4GeneProduct460692 (Entrez Gene)
PIK3R5GeneProduct455085 (Entrez Gene)
PIP2MetaboliteC04637 (Kegg Compound)
PIP3MetaboliteC05981 (Kegg Compound)
PIP4K2AGeneProduct742458 (Entrez Gene)
PIP4K2BGeneProduct746830 (Entrez Gene)
PIP4K2CGeneProduct467044 (Entrez Gene)
PIP5K1AGeneProduct
PIP5K1BGeneProduct464513 (Entrez Gene)
PIP5K1CGeneProduct455590 (Entrez Gene)
PIP5KL1GeneProduct464758 (Entrez Gene)
PPP1R12AGeneProduct452095 (Entrez Gene)
PTK2GeneProduct464422 (Entrez Gene)
PXNGeneProduct452303 (Entrez Gene)
Pik3c2bGeneProduct
RAC1GeneProduct
RAC1P4GeneProduct
RAC2GeneProduct742575 (Entrez Gene)
RAC3GeneProduct
RAF1GeneProduct460182 (Entrez Gene)
RASSF7GeneProduct466303 (Entrez Gene)
RDXGeneProduct466776 (Entrez Gene)
RHOAGeneProduct461014 (Entrez Gene)
RHOXF2GeneProduct473763 (Entrez Gene)
ROCK1GeneProduct455326 (Entrez Gene)
ROCK2GeneProduct470307 (Entrez Gene)
RRAS2GeneProduct451038 (Entrez Gene)
RRASGeneProduct468955 (Entrez Gene)
SLC9A1GeneProduct456669 (Entrez Gene)
SOS1GeneProduct459171 (Entrez Gene)
SOS2GeneProduct
SSH1GeneProduct467124 (Entrez Gene)
SSH2GeneProduct454551 (Entrez Gene)
SSH3GeneProduct
TMSB4XGeneProduct
VAV1GeneProduct455647 (Entrez Gene)
VCLGeneProduct450531 (Entrez Gene)
VIL1GeneProduct470646 (Entrez Gene)
VIL2GeneProduct
WASGeneProduct
WASF1GeneProduct462935 (Entrez Gene)
WASF2GeneProduct456675 (Entrez Gene)

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP944"
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