Valine, leucine and isoleucine degradation (Caenorhabditis elegans)

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Revision as of 13:37, 4 December 2009 by Pieter Giesbertz (Talk | contribs)
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Biosynthesis of steroidsPyrimidine metabolismPropanoate metabolismBiosynthesis of 12-, 14- and 16-membered macrolidesValine, leucine and isoleucine biosynthesisCitrate cycle (TCA cycle)Biosynthesis of type II polyketide backbonehypothetical protein ko:K00186 ko:K00187 ko:K00189 ko:K00188hypothetical protein kat-12-Methylbut-2-enoyl-CoA(3R)-beta-Leucineacdh-8ech-2tag-173ko:K00822beta-Ketoisocaproatebcat-1hacd-1ech-8Thiamin diphosphateL-Isoleucineard-1alh-13-Methyl-2-oxobutanoic acidhypothetical protein acdh-3(R)-Methylmalonyl-CoAko:K00186 ko:K00187 ko:K00189 ko:K00188Acetoacetyl-CoAko:K00248ko:K00186 ko:K00187 ko:K00189 ko:K00188ko:K05607Acetyl-CoAL-Leucinepcca-1bcat-1Succinyl-CoAko:K00186 ko:K00187 ko:K00189 ko:K00188ko:K00186 ko:K00187 ko:K00189 ko:K00188hypothetical protein ech-9hypothetical protein hypothetical protein (S)-3-Methyl-2-oxopentanoic acidech-9ivd-1ech-3Transketolaseacdh-10acdh-8ech-6bcat-1ko:K00186 ko:K00187 ko:K00189 ko:K00188hypothetical protein 4-Methyl-2-oxopentanoatepccb-1hypothetical protein ech-22-Methylpropanoyl-CoA2-Methylprop-2-enoyl-CoAec:5.4.3.7[Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylbutanoyl)dihydrolipoyllysinetag-1732-Methylacetoacetyl-CoAacdh-7hypothetical protein ech-6hypothetical protein ech-1[Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylpropanoyl)dihydrolipoyllysinecpd:C06002cpd:C15980ko:K00186 ko:K00187 ko:K00189 ko:K001883-Methyl-1-hydroxybutyl-ThPP2-Methyl-1-hydroxypropyl-ThPPhypothetical protein hypothetical protein acdh-3hypothetical protein ko:K00248ard-1hypothetical protein tag-173ech-3Thiolasesko:K03334ech-1ko:K00186 ko:K00187 ko:K00189 ko:K00188Enzyme N6-(lipoyl)lysineAcetoacetatehypothetical protein (S)-Methylmalonyl-CoAL-3-Amino-isobutanoateech-5alh-8L-Valineko:K00186 ko:K00187 ko:K00189 ko:K00188tag-173hypothetical protein hypothetical protein hypothetical protein 3-Methylbutanoyl-CoA2-Methyl-1-hydroxybutyl-ThPPhypothetical protein Enzyme N6-(dihydrolipoyl)lysineEnzyme N6-(dihydrolipoyl)lysinehypothetical protein ko:K11538tag-173(S)-3-Hydroxy-3-methylglutaryl-CoAech-1ech-7ec:2.6.1.6ech-23-Methylglutaconyl-CoAMethylmalonatealh-9ko:K00263Propanoyl-CoAhypothetical protein acdh-10hypothetical protein Transketolaseko:K00157acdh-7ko:K05605Transketolase[Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(3-methylbutanoyl)dihydrolipoyllysineko:K07250hypothetical protein 3-Hydroxyisovaleryl-CoAech-73-Methylcrotonyl-CoAech-8ech-3ech-5alh-2Enzyme N6-(dihydrolipoyl)lysinetag-173Thiamin diphosphateEnzyme N6-(lipoyl)lysinehypothetical protein cpd:C05996hypothetical protein cpd:C06001hypothetical protein ko:K05606ech-5(2S,3S)-3-Hydroxy-2-methylbutanoyl-CoAko:K00186 ko:K00187 ko:K00189 ko:K00188ko:K00186 ko:K00187 ko:K00189 ko:K00188ard-1Enzyme N6-(lipoyl)lysinehypothetical protein ko:K00186 ko:K00187 ko:K00189 ko:K00188ech-6acdh-7Transketolaseko:K00263hacd-1Thiamin diphosphateacdh-8acdh-10TransketolaseTransketolaseech-7cpd:C06000mmcm-1


Description

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History

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CompareRevisionActionTimeUserComment
34740view22:47, 13 January 2010KhanspersDeleted pathway: duplicate
33704view13:46, 4 December 2009Pieter GiesbertzSpecify description
33703view13:42, 4 December 2009Pieter GiesbertzSpecify description
33702view13:37, 4 December 2009Pieter GiesbertzSpecify description
33701view13:32, 4 December 2009Pieter Giesbertzchanged gene databases to wormbase
33700view13:26, 4 December 2009Pieter GiesbertzNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
(2S,3S)-3-Hydroxy-2-methylbutanoyl-CoAMetaboliteC04405 (Kegg Compound)
(3R)-beta-LeucineMetaboliteC02486 (Kegg Compound)
(R)-Methylmalonyl-CoAMetaboliteC01213 (Kegg Compound)
(S)-3-Hydroxy-3-methylglutaryl-CoAMetaboliteC00356 (Kegg Compound)
(S)-3-Methyl-2-oxopentanoic acidMetaboliteC00671 (Kegg Compound)
(S)-Methylmalonyl-CoAMetaboliteC00683 (Kegg Compound)
2-Methyl-1-hydroxybutyl-ThPPMetaboliteC15978 (Kegg Compound)
2-Methyl-1-hydroxypropyl-ThPPMetaboliteC15976 (Kegg Compound)
2-Methylacetoacetyl-CoAMetaboliteC03344 (Kegg Compound)
2-Methylbut-2-enoyl-CoAMetaboliteC03345 (Kegg Compound)
2-Methylprop-2-enoyl-CoAMetaboliteC03460 (Kegg Compound)
2-Methylpropanoyl-CoAMetaboliteC00630 (Kegg Compound)
3-Hydroxyisovaleryl-CoAMetaboliteC05998 (Kegg Compound)
3-Methyl-1-hydroxybutyl-ThPPMetaboliteC15974 (Kegg Compound)
3-Methyl-2-oxobutanoic acidMetaboliteC00141 (Kegg Compound)
3-Methylbutanoyl-CoAMetaboliteC02939 (Kegg Compound)
3-Methylcrotonyl-CoAMetaboliteC03069 (Kegg Compound)
3-Methylglutaconyl-CoAMetaboliteC03231 (Kegg Compound)
4-Methyl-2-oxopentanoateMetaboliteC00233 (Kegg Compound)
AcetoacetateMetaboliteC00164 (Kegg Compound)
Acetoacetyl-CoAMetaboliteC00332 (Kegg Compound)
Acetyl-CoAMetaboliteC00024 (Kegg Compound)
Enzyme N6-(dihydrolipoyl)lysineMetaboliteC15973 (Kegg Compound)
Enzyme N6-(lipoyl)lysineMetaboliteC15972 (Kegg Compound)
L-3-Amino-isobutanoateMetaboliteC03284 (Kegg Compound)
L-IsoleucineMetaboliteC00407 (Kegg Compound)
L-LeucineMetaboliteC00123 (Kegg Compound)
L-ValineMetaboliteC00183 (Kegg Compound)
MethylmalonateMetaboliteC02170 (Kegg Compound)
Propanoyl-CoAMetaboliteC00100 (Kegg Compound)
Succinyl-CoAMetaboliteC00091 (Kegg Compound)
Thiamin diphosphateMetaboliteC00068 (Kegg Compound)
ThiolasesGeneProductF53A2.7 (Entrez Gene)

Original kegg element: gene;38;cel:B0303.3 cel:F53A2.7

TransketolaseGeneProductY39E4A.3 (Entrez Gene)

Original kegg element: gene;43;cel:F27D4.5 cel:Y39E4A.3

TransketolaseGeneProductY39E4A.3 (WormBase)

Original kegg element: gene;61;cel:F27D4.5 cel:Y39E4A.3

[Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylbutanoyl)dihydrolipoyllysineMetaboliteC15979 (Kegg Compound)
[Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylpropanoyl)dihydrolipoyllysineMetaboliteC15977 (Kegg Compound)
[Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(3-methylbutanoyl)dihydrolipoyllysineMetaboliteC15975 (Kegg Compound)
acdh-10GeneProductT08G2.3 (Entrez Gene)

Original kegg element: gene;69;cel:K05F1.3 cel:K09H11.1 cel:T08G2.3 cel:T25G12.5

acdh-3GeneProductK06A5.6 (Entrez Gene)

Original kegg element: gene;59;cel:K06A5.6

acdh-7GeneProductT25G12.5 (Entrez Gene)

Original kegg element: gene;69;cel:K05F1.3 cel:K09H11.1 cel:T08G2.3 cel:T25G12.5

acdh-8GeneProductK05F1.3 (Entrez Gene)

Original kegg element: gene;69;cel:K05F1.3 cel:K09H11.1 cel:T08G2.3 cel:T25G12.5

alh-1GeneProductF54D8.3 (WormBase)

Original kegg element: gene;50;cel:F01F1.6 cel:F54D8.3 cel:K04F1.15

alh-2GeneProductK04F1.15 (WormBase)

Original kegg element: gene;50;cel:F01F1.6 cel:F54D8.3 cel:K04F1.15

alh-8GeneProductF13D12.4 (WormBase)

Original kegg element: gene;51;cel:F13D12.4

alh-9GeneProductF01F1.6 (WormBase)

Original kegg element: gene;50;cel:F01F1.6 cel:F54D8.3 cel:K04F1.15

ard-1GeneProductF01G4.2 (Entrez Gene)

Original kegg element: gene;56;cel:F01G4.2

bcat-1GeneProductK02A4.1 (Entrez Gene)

Original kegg element: gene;44;cel:K02A4.1 cel:Y44A6D.5

bcat-1GeneProductK02A4.1 (WormBase)

Original kegg element: gene;63;cel:K02A4.1 cel:Y44A6D.5

beta-KetoisocaproateMetaboliteC03467 (Kegg Compound)
cpd:C05996MetaboliteC05996 (Kegg Compound)
cpd:C06000MetaboliteC06000 (Kegg Compound)
cpd:C06001MetaboliteC06001 (Kegg Compound)
cpd:C06002MetaboliteC06002 (Kegg Compound)
cpd:C15980MetaboliteC15980 (Kegg Compound)
ec:2.6.1.6GeneProduct2.6.1.6 (Kegg enzyme)
ec:5.4.3.7GeneProduct5.4.3.7 (Kegg enzyme)
ech-1GeneProductC29F3.1 (Entrez Gene)

Original kegg element: gene;57;cel:C29F3.1 cel:F38H4.8 cel:F43H9.1 cel:F56B3.5 cel:T05G5.6 cel:T08B2.7 cel:Y105E8A.4

ech-1GeneProductC29F3.1 (WormBase)

Original kegg element: gene;32;cel:C29F3.1 cel:F38H4.8 cel:F43H9.1 cel:F56B3.5 cel:T05G5.6 cel:T08B2.7 cel:Y105E8A.4

ech-2GeneProductF38H4.8 (Entrez Gene)

Original kegg element: gene;57;cel:C29F3.1 cel:F38H4.8 cel:F43H9.1 cel:F56B3.5 cel:T05G5.6 cel:T08B2.7 cel:Y105E8A.4

ech-2GeneProductF38H4.8 (WormBase)

Original kegg element: gene;32;cel:C29F3.1 cel:F38H4.8 cel:F43H9.1 cel:F56B3.5 cel:T05G5.6 cel:T08B2.7 cel:Y105E8A.4

ech-3GeneProductF43H9.1 (Entrez Gene)

Original kegg element: gene;57;cel:C29F3.1 cel:F38H4.8 cel:F43H9.1 cel:F56B3.5 cel:T05G5.6 cel:T08B2.7 cel:Y105E8A.4

ech-3GeneProductF43H9.1 (WormBase)

Original kegg element: gene;32;cel:C29F3.1 cel:F38H4.8 cel:F43H9.1 cel:F56B3.5 cel:T05G5.6 cel:T08B2.7 cel:Y105E8A.4

ech-5GeneProductF56B3.5 (Entrez Gene)

Original kegg element: gene;57;cel:C29F3.1 cel:F38H4.8 cel:F43H9.1 cel:F56B3.5 cel:T05G5.6 cel:T08B2.7 cel:Y105E8A.4

ech-5GeneProductF56B3.5 (WormBase)

Original kegg element: gene;32;cel:C29F3.1 cel:F38H4.8 cel:F43H9.1 cel:F56B3.5 cel:T05G5.6 cel:T08B2.7 cel:Y105E8A.4

ech-6GeneProductT05G5.6 (Entrez Gene)

Original kegg element: gene;57;cel:C29F3.1 cel:F38H4.8 cel:F43H9.1 cel:F56B3.5 cel:T05G5.6 cel:T08B2.7 cel:Y105E8A.4

ech-6GeneProductT05G5.6 (WormBase)

Original kegg element: gene;32;cel:C29F3.1 cel:F38H4.8 cel:F43H9.1 cel:F56B3.5 cel:T05G5.6 cel:T08B2.7 cel:Y105E8A.4

ech-7GeneProductY105E8A.4 (Entrez Gene)

Original kegg element: gene;57;cel:C29F3.1 cel:F38H4.8 cel:F43H9.1 cel:F56B3.5 cel:T05G5.6 cel:T08B2.7 cel:Y105E8A.4

ech-7GeneProductY105E8A.4 (WormBase)

Original kegg element: gene;32;cel:C29F3.1 cel:F38H4.8 cel:F43H9.1 cel:F56B3.5 cel:T05G5.6 cel:T08B2.7 cel:Y105E8A.4

ech-8GeneProductF01G10.2 (Entrez Gene)

Original kegg element: gene;53;cel:B0272.3 cel:F01G10.2 cel:F01G10.3 cel:F01G4.2 cel:F54C8.1 cel:R09B5.6

ech-9GeneProductF01G10.3 (Entrez Gene)

Original kegg element: gene;53;cel:B0272.3 cel:F01G10.2 cel:F01G10.3 cel:F01G4.2 cel:F54C8.1 cel:R09B5.6

hacd-1GeneProductR09B5.6 (Entrez Gene)

Original kegg element: gene;53;cel:B0272.3 cel:F01G10.2 cel:F01G10.3 cel:F01G4.2 cel:F54C8.1 cel:R09B5.6

hypothetical protein GeneProductB0250.5 (Entrez Gene)

Original kegg element: gene;54;cel:B0250.5

hypothetical protein GeneProductB0272.3 (Entrez Gene)

Original kegg element: gene;53;cel:B0272.3 cel:F01G10.2 cel:F01G10.3 cel:F01G4.2 cel:F54C8.1 cel:R09B5.6

hypothetical protein GeneProductB0303.3 (Entrez Gene)

Original kegg element: gene;38;cel:B0303.3 cel:F53A2.7

hypothetical protein GeneProductC05C10.3 (Entrez Gene)

Original kegg element: gene;28;cel:C05C10.3

hypothetical protein GeneProductF25B4.6 (Entrez Gene)

Original kegg element: gene;27;cel:F25B4.6

hypothetical protein GeneProductF32B6.2 (Entrez Gene)

Original kegg element: gene;31;cel:F32B6.2

hypothetical protein GeneProductF54C8.1 (Entrez Gene)

Original kegg element: gene;53;cel:B0272.3 cel:F01G10.2 cel:F01G10.3 cel:F01G4.2 cel:F54C8.1 cel:R09B5.6

hypothetical protein GeneProductK09H11.1 (Entrez Gene)

Original kegg element: gene;69;cel:K05F1.3 cel:K09H11.1 cel:T08G2.3 cel:T25G12.5

hypothetical protein GeneProductLLC1.3 (Entrez Gene)

Original kegg element: gene;17;cel:LLC1.3

hypothetical protein GeneProductT02G5.4 (Entrez Gene)

Original kegg element: gene;21;cel:T02G5.4 cel:T02G5.7 cel:T02G5.8

hypothetical protein GeneProductT02G5.7 (Entrez Gene)

Original kegg element: gene;21;cel:T02G5.4 cel:T02G5.7 cel:T02G5.8

hypothetical protein GeneProductT08B2.7 (Entrez Gene)

Original kegg element: gene;57;cel:C29F3.1 cel:F38H4.8 cel:F43H9.1 cel:F56B3.5 cel:T05G5.6 cel:T08B2.7 cel:Y105E8A.4

hypothetical protein GeneProductY44A6D.5 (Entrez Gene)

Original kegg element: gene;63;cel:K02A4.1 cel:Y44A6D.5

hypothetical protein GeneProductY71G12B.10 (Entrez Gene)

Original kegg element: gene;29;cel:Y71G12B.10

hypothetical protein GeneProductZK669.4 (Entrez Gene)

Original kegg element: gene;62;cel:ZK669.4

ivd-1GeneProductC02B10.1 (Entrez Gene)

Original kegg element: gene;33;cel:C02B10.1

kat-1GeneProductT02G5.8 (WormBase)

Original kegg element: gene;21;cel:T02G5.4 cel:T02G5.7 cel:T02G5.8

ko:K00157GeneProductK00157 (Kegg ortholog)
ko:K00186 ko:K00187 ko:K00189 ko:K00188GeneProductK00186... (Kegg ortholog)
ko:K00248GeneProductK00248 (Kegg ortholog)
ko:K00263GeneProductK00263 (Kegg ortholog)
ko:K00822GeneProductK00822 (Kegg ortholog)
ko:K03334GeneProductK03334 (Kegg ortholog)
ko:K05605GeneProductK05605 (Kegg ortholog)
ko:K05606GeneProductK05606 (Kegg ortholog)
ko:K05607GeneProductK05607 (Kegg ortholog)
ko:K07250GeneProductK07250 (Kegg ortholog)
ko:K11538GeneProductK11538 (Kegg ortholog)
mmcm-1GeneProductZK1058.1 (WormBase)

Original kegg element: gene;46;cel:ZK1058.1

pcca-1GeneProductF27D9.5 (WormBase)

Original kegg element: gene;48;cel:F27D9.5 cel:F52E4.1

pccb-1GeneProductF52E4.1 (WormBase)

Original kegg element: gene;48;cel:F27D9.5 cel:F52E4.1

tag-173GeneProductF27D4.5 (Entrez Gene)

Original kegg element: gene;34;cel:F27D4.5 cel:Y39E4A.3

tag-173GeneProductF27D4.5 (WormBase)

Original kegg element: gene;61;cel:F27D4.5 cel:Y39E4A.3

Annotated Interactions

No annotated interactions

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