IL-3 signaling pathway (Canis familiaris)

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CY->NUPhosphorylationDUbiquitinationNUMT->CYDNucleusECMethylationDCY->NUProteins in a complex interactionAccession Number: NetPath 15DMAMTRecruitmentGODMADDesumoylationDCY->PMEndoplasmic reticulumActivationProteolytic cleavageDeubiquitinationPalmitoylationCYMAControlDMolecule in the pathwayEnzyme complexMitochondrionSumoylationDCY->PMGolgi apparatus(Protein-protein interaction)ENDDDDDeacetylationDMATranslocationDAutophosphorylationDemethylationReceptorDCY->PMDephosphorylationLigandInhibitionCytoplasmAcetylationMolecular AssociationReaction through unknown mechanisms/moleculesMADGlycosylationERPMEndosomeDDPlasma membraneMAExtracellularMAPK8FOXO1CISHBIRC5CSF2RBSYKMAP2K1CRKBADBCL2L1AKT1BCL2PTPN11MAPK3MAPK9GAB1PIK3R2STAT5BHRASPRKCASHC1SRCPRKCBRAPGEF1BCL2L11SPI1GRB2SLC2A1IL3PIK3CAPIK3CDPIK3R1GNB2L1IL3STAT6LCKGSK3BBMXPTK2TNFRSF1BNFKB1GSK3ACDC42MAPK14CRKLIL3IL3MRASGATA2ATF1ATF2Gene SymbolYWHAQMATKPXNCSF2RBBADDNM1RAC2TECSOCS2STAT1CREB1MMP9ID1JAK1RAP1AYWHABBAXHRASRARAMAPK1PPP2CATYK2GATA1PAK1PRKCARAF1STAT3MAPK3HSPB1PILRBMAPK7PTPN6MMP2NFKB1RXRAIL3RAJAK2YWHAZSELPVAV1SOS1KCNIP3FCER2GAB2RPS6KB2STAT5ASOCS3FYNVCLIL3RAPRKACALYNCBLRAC1CHEK1INPP5DSHC1SLC2A1HCKMAPKAPK2FES


Description

No description

Comments

GenMAPP notes 
NetPath:15 - IL-3 Signaling Pathway. NetPath (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the NetPath website until the pathway is published.
GenMAPP remarks 
http://www.netpath.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP286(r21281) with a 87% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

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CompareRevisionActionTimeUserComment
117999view11:25, 23 May 2021EweitzModified title
86925view12:16, 15 July 2016MkutmonOntology Term : 'interleukin-3 signaling pathway' added !
68596view23:22, 5 July 2013MaintBotUpdated to 2013 gpml schema
40756view21:54, 1 March 2011MaintBotRemoved redundant pathway information and comments
35794view06:56, 13 February 2010MaintBotAdded description
34028view18:47, 9 December 2009MaintBotAutomatic update of empty xrefs
31274view19:59, 13 August 2009MaintBotFixed text labels
30719view22:55, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
AKT1GeneProduct490878 (Entrez Gene)
ATF1GeneProduct486545 (Entrez Gene)
ATF2GeneProduct478806 (Entrez Gene)
BADGeneProduct483763 (Entrez Gene)
BAXGeneProduct403523 (Entrez Gene)
BCL2GeneProduct403416 (Entrez Gene)
BCL2L11GeneProduct612867 (Entrez Gene)
BCL2L1GeneProduct403618 (Entrez Gene)
BIRC5GeneProduct442936 (Entrez Gene)
BMXGeneProduct491750 (Entrez Gene)
CBLGeneProduct
CDC42GeneProduct607535 (Entrez Gene)
CHEK1GeneProduct609767 (Entrez Gene)
CISHGeneProduct484757 (Entrez Gene)
CREB1GeneProduct607922 (Entrez Gene)
CRKGeneProduct
CRKLGeneProduct608125 (Entrez Gene)
CSF2RBGeneProduct481276 (Entrez Gene)
DNM1GeneProduct491319 (Entrez Gene)
FCER2GeneProduct
FESGeneProduct609483 (Entrez Gene)
FOXO1GeneProduct477295 (Entrez Gene)
FYNGeneProduct475032 (Entrez Gene)
GAB1GeneProduct483808 (Entrez Gene)
GAB2GeneProduct485167 (Entrez Gene)
GATA1GeneProduct480906 (Entrez Gene)
GATA2GeneProduct484626 (Entrez Gene)
GNB2L1GeneProduct480818 (Entrez Gene)
GRB2GeneProduct483312 (Entrez Gene)
GSK3AGeneProduct484476 (Entrez Gene)
GSK3BGeneProduct478575 (Entrez Gene)
Gene SymbolGeneProduct
HCKGeneProduct485828 (Entrez Gene)
HRASGeneProduct
HRASGeneProduct403735 (Entrez Gene)
HSPB1GeneProduct403979 (Entrez Gene)
ID1GeneProduct609779 (Entrez Gene)
IL3GeneProduct481497 (Entrez Gene)
IL3RAGeneProduct609293 (Entrez Gene)
INPP5DGeneProduct
JAK1GeneProduct442952 (Entrez Gene)
JAK2GeneProduct484185 (Entrez Gene)
KCNIP3GeneProduct609135 (Entrez Gene)
LCKGeneProduct478151 (Entrez Gene)
LYNGeneProduct477886 (Entrez Gene)
MAP2K1GeneProduct478347 (Entrez Gene)
MAPK14GeneProduct403856 (Entrez Gene)
MAPK1GeneProduct477575 (Entrez Gene)
MAPK3GeneProduct486758 (Entrez Gene)
MAPK7GeneProduct489532 (Entrez Gene)
MAPK8GeneProduct477746 (Entrez Gene)
MAPK9GeneProduct474652 (Entrez Gene)
MAPKAPK2GeneProduct490263 (Entrez Gene)
MATKGeneProduct611999 (Entrez Gene)
MMP2GeneProduct403733 (Entrez Gene)
MMP9GeneProduct403885 (Entrez Gene)
MRASGeneProduct477082 (Entrez Gene)
NFKB1GeneProduct442859 (Entrez Gene)
PAK1GeneProduct607885 (Entrez Gene)
PIK3CAGeneProduct488084 (Entrez Gene)
PIK3CDGeneProduct489644 (Entrez Gene)
PIK3R1GeneProduct487235 (Entrez Gene)
PIK3R2GeneProduct609956 (Entrez Gene)
PILRBGeneProduct
PPP2CAGeneProduct403608 (Entrez Gene)
PRKACAGeneProduct403556 (Entrez Gene)
PRKCAGeneProduct490904 (Entrez Gene)
PRKCBGeneProduct489968 (Entrez Gene)
PTK2GeneProduct475108 (Entrez Gene)
PTPN11GeneProduct477488 (Entrez Gene)
PTPN6GeneProduct486717 (Entrez Gene)
PXNGeneProduct486299 (Entrez Gene)
RAC1GeneProduct403955 (Entrez Gene)
RAC2GeneProduct481271 (Entrez Gene)
RAF1GeneProduct484648 (Entrez Gene)
RAP1AGeneProduct483225 (Entrez Gene)
RAPGEF1GeneProduct491286 (Entrez Gene)
RARAGeneProduct480526 (Entrez Gene)
RPS6KB2GeneProduct610499 (Entrez Gene)
RXRAGeneProduct491278 (Entrez Gene)
SELPGeneProduct403994 (Entrez Gene)
SHC1GeneProduct490439 (Entrez Gene)
SLC2A1GeneProduct482437 (Entrez Gene)
SOCS2GeneProduct482603 (Entrez Gene)
SOCS3GeneProduct442949 (Entrez Gene)
SOS1GeneProduct483042 (Entrez Gene)
SPI1GeneProduct611255 (Entrez Gene)
SRCGeneProduct485864 (Entrez Gene)
STAT1GeneProduct488449 (Entrez Gene)
STAT3GeneProduct490967 (Entrez Gene)
STAT5AGeneProduct490968 (Entrez Gene)
STAT5BGeneProduct490969 (Entrez Gene)
STAT6GeneProduct100142679 (Entrez Gene)
SYKGeneProduct484196 (Entrez Gene)
TECGeneProduct482140 (Entrez Gene)
TNFRSF1BGeneProduct487437 (Entrez Gene)
TYK2GeneProduct476714 (Entrez Gene)
VAV1GeneProduct485016 (Entrez Gene)
VCLGeneProduct
YWHABGeneProduct477237 (Entrez Gene)
YWHAQGeneProduct607060 (Entrez Gene)
YWHAZGeneProduct475864 (Entrez Gene)

Annotated Interactions

No annotated interactions
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