Eukaryotic transcription initiation (Mus musculus)

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TFIID5RNA polymerase IITFIIA55TFIIF5533TATATFIIB3553TFIIEGene Regulatory Proteins(small stable RNAs)TATAdsDNA(mRNA, snRNPs)TFIIA5TFIIE3Steps 2) Association of TIFs and RNA polymeraseTFIIF5(large ribosomal RNAs)3Transcription Initiation Factors (TIFs)(recognize surface DNA geometry)RNA pol IIRNA polymerase I3Steps 5) RNA elongation with CDT phosphorylationSteps 1) TBP binds TATA boxTFIIDSteps 4) Transcription elongation by NTPsTATATFIIH3TFIIBproteinTATA Box bindingcell growthSteps 3) DNA melting by association with TFIIH3TFIIHTFIIF5Primary RNA transcriptRNA polymerase IIIPolr2cPolr2aPolr2bGtf2h1Mnat1Taf7Rpo1-3Gtf2a2Gtf2f2CcnhGtf2h3Taf9Polr2ePolr2kGtf2h2TbpPolr2gPolr2iCdk7Polr2jRpo1-4Rpo1-2Polr3hErcc3Polr3dTaf13Taf12IlkErcc2Rpo1-1Taf6Gtf2h4Gtf2e1Polr3bPolr3kPolr3ePolr2fGtf2bGtf2e2Polr2hTaf5


Description

No description

Comments

GenMAPP notes 
Reference: http://www.web-books.com/MoBio/Free/Ch4E.htm
GenMAPP remarks 
right click for notes & references

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Quality Tags

Ontology Terms

 

Bibliography

  1. Lee TI, Young RA; ''Regulation of gene expression by TBP-associated proteins.''; Genes Dev, 1998 PubMed Europe PMC Scholia
  2. Lemon B, Tjian R; ''Orchestrated response: a symphony of transcription factors for gene control.''; Genes Dev, 2000 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
117881view10:21, 23 May 2021EweitzModified title
89957view18:07, 6 October 2016Mkutmonfix unconnected lines
69915view19:37, 11 July 2013Mkutmonfixed unconnected lines
69137view18:16, 8 July 2013MaintBotUpdated to 2013 gpml schema
67216view10:22, 26 June 2013Christine ChichesterOntology Term : 'transcription pathway' added !
41326view00:25, 2 March 2011MaintBotRemoved redundant pathway information and comments
35533view14:04, 12 February 2010Thomasadded literature
35522view13:53, 12 February 2010ThomasModified description
34504view23:33, 16 December 2009KhanspersAdded connectors
26591view18:28, 10 December 2008AlexanderPico
21874view11:32, 14 November 2008MaintBot[[Pathway:Mus musculus:RNA transcription Reactome]] moved to [[Pathway:WP567]]: Moved to stable identifier
8368view13:46, 7 January 2008MaintBot[[Pathway:Mouse:RNA transcription Reactome]] moved to [[Pathway:Mus musculus:RNA transcription Reactome]]: Renaming species
7802view16:18, 18 December 2007MaintBotfixed category names
7287view12:41, 4 November 2007MaintBotAdded categories to GPML
6489view22:19, 22 May 2007Nsalomonisgpml file for [[Mouse:RNA_transcription_Reactome]]

External references

DataNodes

View all...
NameTypeDatabase referenceComment
CcnhGeneProduct66671 (Entrez Gene)
Cdk7GeneProduct12572 (Entrez Gene)
Ercc2GeneProduct13871 (Entrez Gene)
Ercc3GeneProduct13872 (Entrez Gene)
Gtf2a2GeneProduct235459 (Entrez Gene)
Gtf2bGeneProduct229906 (Entrez Gene)
Gtf2e1GeneProduct74197 (Entrez Gene)
Gtf2e2GeneProduct68153 (Entrez Gene)
Gtf2f2GeneProduct68705 (Entrez Gene)
Gtf2h1GeneProduct14884 (Entrez Gene)
Gtf2h2GeneProduct23894 (Entrez Gene)
Gtf2h3GeneProduct209357 (Entrez Gene)
Gtf2h4GeneProduct14885 (Entrez Gene)
IlkGeneProduct16202 (Entrez Gene)
Mnat1GeneProduct17420 (Entrez Gene)
Polr2aGeneProduct20020 (Entrez Gene)
Polr2bGeneProduct231329 (Entrez Gene)
Polr2cGeneProduct20021 (Entrez Gene)
Polr2eGeneProduct66420 (Entrez Gene)
Polr2fGeneProduct110812 (Entrez Gene)
Polr2gGeneProduct67710 (Entrez Gene)
Polr2hGeneProduct245841 (Entrez Gene)
Polr2iGeneProduct69920 (Entrez Gene)
Polr2jGeneProduct20022 (Entrez Gene)
Polr2kGeneProduct17749 (Entrez Gene)
Polr3bGeneProduct70428 (Entrez Gene)
Polr3dGeneProduct67065 (Entrez Gene)
Polr3eGeneProduct26939 (Entrez Gene)
Polr3hGeneProduct78929 (Entrez Gene)
Polr3kGeneProduct67005 (Entrez Gene)
Rpo1-1GeneProduct20016 (Entrez Gene)
Rpo1-2GeneProduct20017 (Entrez Gene)
Rpo1-3GeneProduct20018 (Entrez Gene)
Rpo1-4GeneProduct20019 (Entrez Gene)
Taf12GeneProduct66464 (Entrez Gene)
Taf13GeneProduct99730 (Entrez Gene)
Taf5GeneProduct226182 (Entrez Gene)
Taf6GeneProduct21343 (Entrez Gene)
Taf7GeneProduct24074 (Entrez Gene)
Taf9GeneProduct108143 (Entrez Gene)
TbpGeneProduct21374 (Entrez Gene)

Annotated Interactions

No annotated interactions
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