Eukaryotic transcription initiation (Rattus norvegicus)

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TFIIF53Steps 5) RNA elongation with CDT phosphorylationTFIID5Transcription Initiation Factors (TIFs)3TFIIBRNA pol IIcell growthTFIIH5RNA polymerase IITFIIHPrimary RNA transcriptTATA(mRNA, snRNPs)TFIIE353TFIIFTATA Box bindingproteinTFIIFTFIIASteps 2) Association of TIFs and RNA polymeraseTFIIERNA polymerase IIIRNA polymerase I(small stable RNAs)TATASteps 4) Transcription elongation by NTPs(recognize surface DNA geometry)Gene Regulatory ProteinsTFIIDSteps 3) DNA melting by association with TFIIH3Steps 1) TBP binds TATA boxdsDNA3(large ribosomal RNAs)5553535TATA35TFIIATFIIBCdk7Polr3kGstt2Polr2jGtf2e2Gtf2bPolr1aPolr3bGtf2h2Gtf2e1POLR1DPOLR2KPolr2fTaf9Polr2ePolr1bGtf2h1Polr2gCcnhGtf2a2Taf6Polr3hPolr3dPolr3ePolr2cIlkPolr2bPOLR2HGtf2f2Mnat1Taf13Gtf2h4Ercc3Gtf2h3Polr2iERCC2Taf5Taf7TbpTAF12Polr2a


Description

No description

Comments

GenMAPP notes 
Reference: http://www.web-books.com/MoBio/Free/Ch4E.htm
GenMAPP remarks 
right click for notes & references
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP405(r29565) with a 87% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Lee TI, Young RA; ''Regulation of gene expression by TBP-associated proteins.''; Genes Dev, 1998 PubMed Europe PMC Scholia
  2. Lemon B, Tjian R; ''Orchestrated response: a symphony of transcription factors for gene control.''; Genes Dev, 2000 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
116960view10:09, 16 May 2021EweitzModified title
69450view19:06, 8 July 2013MaintBotUpdated to 2013 gpml schema
67214view10:22, 26 June 2013Christine ChichesterOntology Term : 'transcription pathway' added !
47778view05:46, 6 April 2012Khanspersupdated xref
41779view02:42, 2 March 2011MaintBotRemoved redundant pathway information and comments
35532view14:03, 12 February 2010Thomasadded literature
35521view13:53, 12 February 2010ThomasModified description
34505view23:39, 16 December 2009KhanspersAdded connectors
34147view19:35, 9 December 2009MaintBotAutomatic update of empty xrefs
32446view17:20, 15 August 2009MaintBotFixed text labels
32120view13:51, 14 August 2009MaintBotFixed group labels
31465view21:17, 13 August 2009MaintBotFixed text labels
31008view01:04, 30 July 2009MaintBotConverted from Homo sapiens
21712view11:32, 14 November 2008MaintBot[[Pathway:Rattus norvegicus:RNA transcription Reactome]] moved to [[Pathway:WP491]]: Moved to stable identifier
8370view13:46, 7 January 2008MaintBot[[Pathway:Rat:RNA transcription Reactome]] moved to [[Pathway:Rattus norvegicus:RNA transcription Reactome]]: Renaming species
7803view16:18, 18 December 2007MaintBotfixed category names
7288view12:41, 4 November 2007MaintBotAdded categories to GPML
6589view22:20, 22 May 2007Nsalomonisgpml file for [[Rat:RNA_transcription_Reactome]]

External references

DataNodes

View all...
NameTypeDatabase referenceComment
CcnhGeneProduct84389 (Entrez Gene)
Cdk7GeneProduct171150 (Entrez Gene)
ERCC2GeneProduct308415 (Entrez Gene)
Ercc3GeneProduct291703 (Entrez Gene)
Gstt2GeneProduct29487 (Entrez Gene)
Gtf2a2GeneProduct83828 (Entrez Gene)
Gtf2bGeneProduct81673 (Entrez Gene)
Gtf2e1GeneProduct303918 (Entrez Gene)
Gtf2e2GeneProduct306516 (Entrez Gene)
Gtf2f2GeneProduct81674 (Entrez Gene)
Gtf2h1GeneProduct361580 (Entrez Gene)
Gtf2h2GeneProduct294693 (Entrez Gene)
Gtf2h3GeneProduct288651 (Entrez Gene)
Gtf2h4GeneProduct294236 (Entrez Gene)
IlkGeneProduct170922 (Entrez Gene)
Mnat1GeneProduct266713 (Entrez Gene)
POLR1DGeneProduct
POLR2HGeneProduct498109 (Entrez Gene)
POLR2KGeneProduct309224 (Entrez Gene)
Polr1aGeneProduct83581 (Entrez Gene)
Polr1bGeneProduct83582 (Entrez Gene)
Polr2aGeneProduct363633 (Entrez Gene)
Polr2bGeneProduct289561 (Entrez Gene)
Polr2cGeneProduct361365 (Entrez Gene)
Polr2eGeneProduct690966 (Entrez Gene)
Polr2fGeneProduct83503 (Entrez Gene)
Polr2gGeneProduct117017 (Entrez Gene)
Polr2iGeneProduct292778 (Entrez Gene)
Polr2jGeneProduct288588 (Entrez Gene)
Polr3bGeneProduct362858 (Entrez Gene)
Polr3dGeneProduct306012 (Entrez Gene)
Polr3eGeneProduct361640 (Entrez Gene)
Polr3hGeneProduct300088 (Entrez Gene)
Polr3kGeneProduct366277 (Entrez Gene)
TAF12GeneProduct682902 (Entrez Gene)
Taf13GeneProduct310784 (Entrez Gene)
Taf5GeneProduct294018 (Entrez Gene)
Taf6GeneProduct288533 (Entrez Gene)
Taf7GeneProduct307485 (Entrez Gene)
Taf9GeneProduct373541 (Entrez Gene)
TbpGeneProduct117526 (Entrez Gene)

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP491"
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