HG_Shared_Pathway-MYCN-NOTCH (Homo sapiens)
From WikiPathways
Description
Reflects the current status of research in the Human Genetics Department of the AMC in Amsterdam.
This is confidential. The pathway organizes results from wet lab experiments in the IMR32 neuroblastoma cell line.
Readouts are from Affymetrix array, western blotQuality Tags
Ontology Terms
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History
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External references
DataNodes
| View all... |
| Name | Type | Database reference | Comment |
|---|---|---|---|
| ASCL1 | GeneProduct | ||
| AURKB | GeneProduct | ||
| BMP4 | GeneProduct | ||
| BOREALIN | GeneProduct | ||
| CCNA1/2 | GeneProduct | ||
| CCNB1/2 | GeneProduct | ||
| CCND1 | GeneProduct | ||
| CCNE1/2 | GeneProduct | ||
| CCNG2 | GeneProduct | ||
| CDCA3 (TOME1) | GeneProduct | ||
| CDK1 | GeneProduct | ||
| CDK2 | GeneProduct | 1017 (Entrez Gene)  | |
| CDK4/6 | GeneProduct | ||
| CDKN1A (p21) | GeneProduct | ||
| CDKN1B (p27) | GeneProduct | ||
| CDKN1C (p57) | GeneProduct | 1786 (Entrez Gene) | 38 Genes additionally regulated |
| CDKN2A (p16) | GeneProduct | ||
| ERK | GeneProduct | 5595 (Entrez Gene) | ERK |
| ESCO2 | GeneProduct | ||
| FOXO3 | GeneProduct | 2309 (Entrez Gene) | |
| FOXR1 | GeneProduct | ||
| HEY1 | GeneProduct | ||
| LIN28B | GeneProduct | ||
| MEK | GeneProduct | 4214 (Entrez Gene) | MEK |
| MSX1 | GeneProduct | 4487 (Entrez Gene) | |
| MYCN | GeneProduct | 4613 (Entrez Gene) | |
| NF1 | GeneProduct | 4763 (Entrez Gene) | |
| NOTCH3-IC | GeneProduct | 4854 (Entrez Gene) | |
| P | Metabolite | ||
| P-AKT | GeneProduct | 208 (Entrez Gene) | |
| P-FOXO3 | GeneProduct | 2309 (Entrez Gene) | |
| PHOX2B | GeneProduct | 8929 (Entrez Gene) | |
| PIK3CA | GeneProduct | 5290 (Entrez Gene) | Alias p110 |
| PIK3R1 | GeneProduct | 5295 (Entrez Gene) | Alias p85a |
| Pre-RC | GeneProduct | ||
| RAS | GeneProduct | 4893 (Entrez Gene) | And other RAS proteins? |
| RB1 | GeneProduct | 5925 (Entrez Gene) | |
| SURVIVIN | GeneProduct | ||
| TACC2 | GeneProduct | ||
| TCF4 | GeneProduct | ||
| TP53 | GeneProduct |
Annotated Interactions
No annotated interactions
