VEGF-receptor signal transduction (Rattus norvegicus)

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Y-1059Y-1175Y-1214Y-996Y-10541Playing catch and releasePermeabilityProliferationERFocal adhesion Turn OverHematopoetic Stem CellsCa2+NucleusMacrofages / MonocytesY-951PGi2 ProductionGene TranscriptionSurvivalActin ReorganisationNO+MigrationGRB2PKCSPKVRAPVEGF-AIP3PI3KPLC-yDAGsVEGFR-1Akt/PKBPIP3VEGF-CVEGF-BPlGFVEGFR-2VEGFR-1VEGFR-3VEGF-AVEGF-BPlGFVEGF-DVEGF-CVEGF-DVEGF-CVEGF-DVEGF-APLC-ySckPIP2Lymphatic EndothliumVascular Endothelium / Lymphatic EndotheliumVEGF-AVEGF-BPlGFPIP2Ca2+Ca2+RafMEKRasERKcPLA2FAKPaxillinp38MAPKSrcMAPKAPK2/3HSP27Y-1337SHCPKCp42 MAPKp44 MAPKBADCaspase 9eNOSCa2+RACCa2+Ca2+Ca2+


Description

VEGF Signal transduction in haematopoeitic stem cells, macrophages, monocyten, vascular endothelium and lymphatic endothelium.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Cross MJ, Dixelius J, Matsumoto T, Claesson-Welsh L; ''VEGF-receptor signal transduction.''; Trends Biochem Sci, 2003 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
126412view20:11, 26 April 2023EgonwLicense is CCZero
117027view13:01, 16 May 2021EweitzModified title
106968view13:42, 17 September 2019MaintBotHMDB identifier normalization
82982view00:04, 17 November 2015Mkutmonfixed outdated identifier
78472view10:27, 7 January 2015MaintBotadded missing graphIds
72083view21:14, 24 October 2013Mkutmonadded datasource to p44 MAPK
71780view20:31, 17 October 2013MaintBotAutomated update of data sources
71297view16:57, 17 October 2013MaintBotAutomated update of data sources
69360view18:54, 8 July 2013MaintBotUpdated to 2013 gpml schema
67742view11:57, 26 June 2013DdiglesOntology Term : 'vascular endothelial growth factor signaling pathway' added !
58926view05:11, 21 February 2013MaintBotUpdated Ensembl and UniProt data source
44971view14:08, 6 October 2011Mkutmonconnected some lines
42197view20:54, 7 March 2011KhanspersModified categories
41674view02:35, 2 March 2011MaintBotRemoved redundant pathway information and comments
40388view14:32, 23 February 2011MLW2011Specify description
40387view14:23, 23 February 2011MLW2011Periodical save, work in progress
40384view14:11, 23 February 2011MLW2011Modified description
40383view14:06, 23 February 2011MLW2011VEGF-receptor Signal Transduction
40382view14:05, 23 February 2011MLW2011Periodical save, work in progress
40380view13:55, 23 February 2011MLW2011Periodical save, work in progress
40376view13:45, 23 February 2011MLW2011Periodical save, work in progress
40367view13:35, 23 February 2011MLW2011Periodical save, work in progress
40362view13:24, 23 February 2011MLW2011Periodical save, work in progress
40355view13:14, 23 February 2011MLW2011Periodical save, work in progress
40351view13:04, 23 February 2011MLW2011Periodical save, work in progress
40347view12:54, 23 February 2011MLW2011Periodical save, work in progress
40343view12:44, 23 February 2011MLW2011Periodical save, work in progress
40340view12:34, 23 February 2011MLW2011Periodical save, work in progress
40337view12:23, 23 February 2011MLW2011Periodical save, work in progress
40333view12:13, 23 February 2011MLW2011Periodical save, work in progress
40327view12:03, 23 February 2011MLW2011Periodical save, work in progress
40324view11:53, 23 February 2011MLW2011Periodical save, work in progress
40318view11:43, 23 February 2011MLW2011New pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
Akt/PKBGeneProductENSRNOG00000028629 (Ensembl Rat)
BADGeneProductENSRNOG00000021147 (Ensembl Rat)
Caspase 9GeneProductENSRNOG00000012944 (Ensembl Rat)
DAGGeneProductENSRNOG00000019400 (Ensembl Rat)
ERKProtein
FAKProtein
GRB2GeneProductENSRNOG00000003990 (Ensembl Rat)
HSP27GeneProductENSRNOG00000017795 (Ensembl Rat)
IP3MetaboliteHMDB01498 (HMDB)
MAPKAPK2/3GeneProduct289014 (Entrez Gene)
MEKProtein
PI3KGeneProductENSRNOG00000000145 (Ensembl Rat)
PIP2MetaboliteHMDB10032 (HMDB)
PIP3MetaboliteHMDB10147 (HMDB)
PKCGeneProduct
PKCProtein
PLC-yProtein
PaxillinProtein
PlGFProteinQ63434 (Uniprot/TrEMBL)
RACGeneProductENSRNOG00000001068 (Ensembl Rat)
RafProtein
RasGeneProduct
SHCGeneProductENSRNOG00000020657 (Ensembl Rat)
SPKProteinP0C6C0 (Uniprot/TrEMBL)
SckProtein
SrcProtein
VEGF-AGeneProductENSRNOG00000019598 (Ensembl Rat)
VEGF-BGeneProductENSRNOG00000021156 (Ensembl Rat)
VEGF-CGeneProductENSRNOG00000011416 (Ensembl Rat)
VEGF-DProteinO35251 (Uniprot/TrEMBL)
VEGFR-1GeneProduct
VEGFR-2GeneProduct
VEGFR-3GeneProduct
VRAPProtein
cPLA2Protein
eNOSGeneProductENSRNOG00000009348 (Ensembl Rat)
p38MAPKProteinENSRNOG00000006984 (Uniprot/TrEMBL)
p42 MAPKGeneProduct
p44 MAPKGeneProduct
sVEGFR-1GeneProduct

Annotated Interactions

No annotated interactions

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