Regulation of actin cytoskeleton (Danio rerio)
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Growth Factor (GF)
Stabilization
of actin
Chemotatic factor
GPCR
Actin polymerization
stress fiber
Filipodia
GF
Focal adhesion
pathway
MAPK Signaling
pathway
Lamellipodia
PI3K
PI3K
RTK
GPCR
RTK
Actin polymerization
RAS
Actin
polymerization
+p
?
-p
Focal complex
assembly
Adherens junction
pathway
Focal adhesion
pathway
Gene Expression
Chemotactic factor
RAS
Actomyosin
assembly contraction
Focal adhesion
assembly
stress fiber
PDGFRA
PFN1
mapk3
ARPC5
rock2a
VAV1
C11orf13
fgfr3
PIP5K2C
LOC100150701
ACTB
MYLK
Bradykinin
fgf5
tpte
FGF20
nras
PDGFB
BAIAP2
FGF6
PIP5K1A
LOC558288
VIL2
cfl2
pik3r2
PAK6
FGF1
tpte
slc9a1
ARHGEF1
CFL1
LOC792708
LOC100004938
fgf16
Pik3c2b
zgc:92316
ROCK1
fgf8a
fgf14
zgc:153713
FGF2
FGF22
zgc:77231
tpte
SSH2
ARHGEF7
limk1
rac2
pik3cd
PDGFA
ACTN1
mras
egfr
LOC570868
iqgap1
ACTB
si:dkey-234n3.1
mapk1
ptk2.1
Acetylcholine
raf1
Apc2
fgf17
pak1
tpte
LOC560360
LOC442775
tpte
pik3c3
pik3r3
LOC100004036
APC
mapk6
fgf3
chrm3
rras2
ACTB
rdx
PIP2
chrm2a
dock1
ARPC5
GRLF1
PFN1
fgf23
RAC1P4
DKEYP-88F5.5
zgc:77033
fgf10a
fgfr4
f2
FGF13
mos
fgf12
BAIAP2
pak2a
tpte
gna12
LOC568935
chrm5a
LOC560360
rac1
FGF11
CH211-130M23.4
PIP2
DKEY-242K1.1
pdgfrb
myh10
fgf7
LOC557176
rras
ACTG1
im:7148788
LOC558498
ppp1r12a
fgfr1a
gng12
CH211-67F24.8
mapk4
FGF9
zgc:172250
LOC559017
gna13a
SSH1
WASF2
LPS
LOC561737
cdc42l
ACTG1
zgc:136560
SOS1
ENAH
PAK3
fn1
pxn
ACTG1
CD14
braf
zgc:92014
RAC3
CH211-279L9.5
zgc:194528
LOC100149843
msn
bdkrb1
PIP3
map2k1
TMSB4X
FGF18
MYL3
crk
vcl
FGF21
vcl
kras
CSK
fgf4
fgfr2
pak7
gsna
egf
vil1l
si:dkey-24l11.7
wu:fb92a07
zgc:175192
LOC564771
LOC558288
pip5k1a
wasb
Description
No description
Comments
GenMAPP notes
http://www.genome.jp/kegg/pathway/hsa/hsa04810.html
GenMAPP remarks
Adapted from KEGG (right-click to see notes)
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP51(r20783)
with a 66% conversion rate.
Try the New WikiPathways
View approved pathways at
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Quality Tags
Ontology Terms
Saving...
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Bibliography
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History
View all...
Compare
Revision
Action
Time
User
Comment
116903
view
11:33, 15 May 2021
Eweitz
Modified title
72128
view
07:53, 25 October 2013
Mkutmon
added datasource to pathway data nodes
71535
view
19:23, 17 October 2013
MaintBot
Automated update of data sources
68684
view
05:44, 6 July 2013
MaintBot
Updated to 2013 gpml schema
47916
view
21:38, 18 April 2012
Khanspers
Removed redundant information
47915
view
21:37, 18 April 2012
Khanspers
Updating from human to fix xref duplication
40858
view
22:20, 1 March 2011
MaintBot
Removed redundant pathway information and comments
34239
view
21:40, 9 December 2009
MaintBot
Automatic update of empty xrefs
32340
view
13:34, 15 August 2009
MaintBot
Fixed text labels
31956
view
13:03, 14 August 2009
MaintBot
Fixed group labels
31386
view
20:44, 13 August 2009
MaintBot
Fixed text labels
31092
view
01:38, 30 July 2009
MaintBot
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
ACTB
GeneProduct
ACTG1
GeneProduct
ACTN1
GeneProduct
560400 (Entrez Gene)
APC
GeneProduct
386762 (Entrez Gene)
ARHGEF1
GeneProduct
368266 (Entrez Gene)
ARHGEF7
GeneProduct
ARPC5
GeneProduct
Acetylcholine
Metabolite
Apc2
GeneProduct
BAIAP2
GeneProduct
Bradykinin
Metabolite
C11orf13
GeneProduct
CD14
GeneProduct
CFL1
GeneProduct
406738 (Entrez Gene)
CH211-130M23.4
GeneProduct
558477 (Entrez Gene)
CH211-279L9.5
GeneProduct
555920 (Entrez Gene)
CH211-67F24.8
GeneProduct
561670 (Entrez Gene)
CSK
GeneProduct
556454 (Entrez Gene)
DKEY-242K1.1
GeneProduct
560305 (Entrez Gene)
DKEYP-88F5.5
GeneProduct
100001221 (Entrez Gene)
ENAH
GeneProduct
563805 (Entrez Gene)
FGF11
GeneProduct
497640 (Entrez Gene)
FGF13
GeneProduct
492758 (Entrez Gene)
FGF1
GeneProduct
393733 (Entrez Gene)
FGF18
GeneProduct
FGF20
GeneProduct
FGF21
GeneProduct
724048 (Entrez Gene)
FGF22
GeneProduct
100005852 (Entrez Gene)
FGF2
GeneProduct
404231 (Entrez Gene)
FGF6
GeneProduct
FGF9
GeneProduct
GRLF1
GeneProduct
LOC100004036
GeneProduct
100004036 (Entrez Gene)
LOC100004938
GeneProduct
100004938 (Entrez Gene)
LOC100149843
GeneProduct
100149843 (Entrez Gene)
LOC100150701
GeneProduct
100150701 (Entrez Gene)
LOC442775
GeneProduct
LOC557176
GeneProduct
557176 (Entrez Gene)
LOC558288
GeneProduct
558288 (Entrez Gene)
LOC558498
GeneProduct
558498 (Entrez Gene)
LOC559017
GeneProduct
559017 (Entrez Gene)
LOC560360
GeneProduct
560360 (Entrez Gene)
LOC561737
GeneProduct
561737 (Entrez Gene)
LOC564771
GeneProduct
564771 (Entrez Gene)
LOC568935
GeneProduct
568935 (Entrez Gene)
LOC570868
GeneProduct
570868 (Entrez Gene)
LOC792708
GeneProduct
792708 (Entrez Gene)
LPS
Metabolite
C00338 (Kegg Compound)
MYL3
GeneProduct
MYLK
GeneProduct
569510 (Entrez Gene)
PAK3
GeneProduct
PAK6
GeneProduct
PDGFA
GeneProduct
PDGFB
GeneProduct
565324 (Entrez Gene)
PDGFRA
GeneProduct
30745 (Entrez Gene)
PFN1
GeneProduct
799355 (Entrez Gene)
PIP2
Metabolite
C04637 (Kegg Compound)
PIP3
Metabolite
C05981 (Kegg Compound)
PIP5K1A
GeneProduct
553629 (Entrez Gene)
PIP5K2C
GeneProduct
Pik3c2b
GeneProduct
RAC1P4
GeneProduct
RAC3
GeneProduct
437027 (Entrez Gene)
ROCK1
GeneProduct
SOS1
GeneProduct
SSH1
GeneProduct
559238 (Entrez Gene)
SSH2
GeneProduct
325085 (Entrez Gene)
TMSB4X
GeneProduct
VAV1
GeneProduct
VIL2
GeneProduct
WASF2
GeneProduct
bdkrb1
GeneProduct
368199 (Entrez Gene)
braf
GeneProduct
403065 (Entrez Gene)
cdc42l
GeneProduct
793158 (Entrez Gene)
cfl2
GeneProduct
403001 (Entrez Gene)
chrm2a
GeneProduct
352938 (Entrez Gene)
chrm3
GeneProduct
571679 (Entrez Gene)
chrm5a
GeneProduct
553978 (Entrez Gene)
crk
GeneProduct
445234 (Entrez Gene)
dock1
GeneProduct
572187 (Entrez Gene)
egf
GeneProduct
403045 (Entrez Gene)
egfr
GeneProduct
378478 (Entrez Gene)
f2
GeneProduct
325881 (Entrez Gene)
fgf10a
GeneProduct
359830 (Entrez Gene)
fgf12
GeneProduct
777735 (Entrez Gene)
fgf14
GeneProduct
497642 (Entrez Gene)
fgf16
GeneProduct
692065 (Entrez Gene)
fgf17
GeneProduct
407737 (Entrez Gene)
fgf23
GeneProduct
494456 (Entrez Gene)
fgf3
GeneProduct
30549 (Entrez Gene)
fgf4
GeneProduct
570435 (Entrez Gene)
fgf5
GeneProduct
494454 (Entrez Gene)
fgf7
GeneProduct
493181 (Entrez Gene)
fgf8a
GeneProduct
30538 (Entrez Gene)
fgfr1a
GeneProduct
30705 (Entrez Gene)
fgfr2
GeneProduct
352940 (Entrez Gene)
fgfr3
GeneProduct
58129 (Entrez Gene)
fgfr4
GeneProduct
100000160 (Entrez Gene)
fn1
GeneProduct
100005469 (Entrez Gene)
gna12
GeneProduct
503589 (Entrez Gene)
gna13a
GeneProduct
326825 (Entrez Gene)
gng12
GeneProduct
406604 (Entrez Gene)
gsna
GeneProduct
321099 (Entrez Gene)
im:7148788
GeneProduct
564088 (Entrez Gene)
iqgap1
GeneProduct
100002928 (Entrez Gene)
kras
GeneProduct
445289 (Entrez Gene)
limk1
GeneProduct
735292 (Entrez Gene)
map2k1
GeneProduct
406728 (Entrez Gene)
mapk1
GeneProduct
360144 (Entrez Gene)
mapk3
GeneProduct
399480 (Entrez Gene)
mapk4
GeneProduct
406782 (Entrez Gene)
mapk6
GeneProduct
565830 (Entrez Gene)
mos
GeneProduct
795517 (Entrez Gene)
mras
GeneProduct
564799 (Entrez Gene)
msn
GeneProduct
553434 (Entrez Gene)
myh10
GeneProduct
555454 (Entrez Gene)
nras
GeneProduct
30380 (Entrez Gene)
pak1
GeneProduct
373103 (Entrez Gene)
pak2a
GeneProduct
266749 (Entrez Gene)
pak7
GeneProduct
405898 (Entrez Gene)
pdgfrb
GeneProduct
559529 (Entrez Gene)
pik3c3
GeneProduct
548346 (Entrez Gene)
pik3cd
GeneProduct
394174 (Entrez Gene)
pik3r2
GeneProduct
404211 (Entrez Gene)
pik3r3
GeneProduct
100000252 (Entrez Gene)
pip5k1a
GeneProduct
553629 (Entrez Gene)
ppp1r12a
GeneProduct
445393 (Entrez Gene)
ptk2.1
GeneProduct
142986 (Entrez Gene)
pxn
GeneProduct
399546 (Entrez Gene)
rac1
GeneProduct
327204 (Entrez Gene)
rac2
GeneProduct
415151 (Entrez Gene)
raf1
GeneProduct
30716 (Entrez Gene)
rdx
GeneProduct
286739 (Entrez Gene)
rock2a
GeneProduct
317747 (Entrez Gene)
rras2
GeneProduct
550513 (Entrez Gene)
rras
GeneProduct
449660 (Entrez Gene)
si:dkey-234n3.1
GeneProduct
561894 (Entrez Gene)
si:dkey-24l11.7
GeneProduct
571356 (Entrez Gene)
slc9a1
GeneProduct
795135 (Entrez Gene)
tpte
GeneProduct
327292 (Entrez Gene)
vcl
GeneProduct
552980 (Entrez Gene)
vil1l
GeneProduct
393207 (Entrez Gene)
wasb
GeneProduct
335158 (Entrez Gene)
wu:fb92a07
GeneProduct
100002263 (Entrez Gene)
zgc:136560
GeneProduct
692331 (Entrez Gene)
zgc:153713
GeneProduct
751630 (Entrez Gene)
zgc:172250
GeneProduct
100002225 (Entrez Gene)
zgc:175192
GeneProduct
568309 (Entrez Gene)
zgc:194528
GeneProduct
100002872 (Entrez Gene)
zgc:77033
GeneProduct
406598 (Entrez Gene)
zgc:77231
GeneProduct
336165 (Entrez Gene)
zgc:92014
GeneProduct
431769 (Entrez Gene)
zgc:92316
GeneProduct
447840 (Entrez Gene)
Annotated Interactions
No annotated interactions
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Try the New WikiPathways
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Annotated Interactions
No annotated interactions