Methylation (Pan troglodytes)

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1, 2O-methylationN-methylationS-methylationSAM synthesis (co-substrate)MAT2BN-methylated substratePNMTL-MethionineATPPhosphateTPMT_PANTRNNMTPhosphateMAT2ASubstrateS-AdenosylhomocysteineS-methylated substrateS-AdenosylmethionineS-AdenosylhomocysteineCOMTINMTS-AdenosylmethionineQ9N2A9_PANTRS-AdenosylmethionineO-methylated substrateMAT1AS-Adenosylhomocysteine


Description

No description

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP704(r30265) with a 100% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Testa B, Kramer SD; ''The biochemistry of drug metabolism--an introduction: part 4. reactions of conjugation and their enzymes.''; Chem Biodivers, 2008 PubMed Europe PMC Scholia
  2. Weinshilboum RM; ''Pharmacogenomics: catechol O-methyltransferase to thiopurine S-methyltransferase.''; Cell Mol Neurobiol, 2006 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
118294view12:13, 26 May 2021EweitzModified title
106920view13:39, 17 September 2019MaintBotHMDB identifier normalization
69233view18:34, 8 July 2013MaintBotUpdated to 2013 gpml schema
58901view04:47, 21 February 2013MaintBotUpdated Ensembl and UniProt data source
41537view01:57, 2 March 2011MaintBotRemoved redundant pathway information and comments
33538view09:36, 1 December 2009MaintBotRemoved group label
30443view21:24, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ATPMetaboliteHMDB00538 (HMDB)
COMTGeneProductENSPTRG00000014070 (Ensembl Chimp)
INMTGeneProductENSPTRG00000019045 (Ensembl Chimp)
L-MethionineMetaboliteHMDB00696 (HMDB)
MAT1AGeneProductENSPTRG00000002682 (Ensembl Chimp)
MAT2AGeneProductENSPTRG00000012134 (Ensembl Chimp)
MAT2BGeneProductENSPTRG00000017504 (Ensembl Chimp)
N-methylated substrateMetabolite
NNMTGeneProductENSPTRG00000004303 (Ensembl Chimp)
O-methylated substrateMetabolite
PNMTGeneProductENSPTRG00000009098 (Ensembl Chimp)
PhosphateMetaboliteHMDB01429 (HMDB)
Q9N2A9_PANTRGeneProductENSPTRG00000012503 (Ensembl Chimp)
S-AdenosylhomocysteineMetaboliteHMDB00939 (HMDB)
S-AdenosylmethionineMetaboliteHMDB01185 (HMDB)
S-methylated substrateMetabolite
SubstrateMetabolite
TPMT_PANTRGeneProductENSPTRG00000017756 (Ensembl Chimp)

Annotated Interactions

No annotated interactions
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