IL-4 signaling pathway (Rattus norvegicus)

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Molecule in the pathwayCY -> PMDNUExtracellularDesumoylationCY -> PMMethylationInhibitionCY -> PMCytoplasmDemethylationCY -> PMECPlasma membraneGOPalmitoylationReaction through unknown mechanisms/moleculesDDEndoplasmic reticulumDLigandUbiquitinationAccession Number: NetPath 16AutophosphorylationEndosomeDeubiquitinationAcetylationDActivationDephosphorylationMolecular associationPhosphorylationENProteins in a complex interactionTranslocationControlCY -> NUProteolytic cleavageMitochondrionERMTDSumoylationGolgi apparatusDPMCY -> NURecruitmentCYEnzyme complexDNucleus(Protein-protein interaction)ReceptorDeacetylationDGlycosylationPrkcdIrs1Nfkb1PrkciJak2Akt1Nfkb1Sfpi1Pik3r1Ptpn6Atf2Il2rgPik3r2Il4Jak2Rasa1Mapk3Stat6Mapk1SrcPrkciMapk14PrkcnTYK2Ptpn11PrkczPik3cdJak1MAPK11Il4NCF1Ptk2Il13ra1RGD1564914Socs1FynMapk14Adrbk2Gene SymbolPIK3CADok2RGD1564499Il4raBcl2l1Ep300Stat6BadPrkczPlcg1Stat1Ets1Lck mappedSocs3Sos1Inpp5dRGD1561386Jak3Stat5aCrebbpHmga1HIST2H3CJak1Il4raStat6Rps6kb1Elk1Stat6RGD1564385Shc1Irs2Cxcr4Grb2PrkcnStat6RelaPrkcdPawr


Description

No description

Comments

GenMAPP notes 
NetPath 16 - IL-4 Signaling Pathway

NetPath (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the NetPath website until the pathway is published.

GenMAPP remarks 
http://www.netpath.org

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Ontology Terms

 

Bibliography

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History

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CompareRevisionActionTimeUserComment
117987view11:23, 23 May 2021EweitzModified title
69413view19:01, 8 July 2013MaintBotUpdated to 2013 gpml schema
67377view10:44, 26 June 2013Christine ChichesterOntology Term : 'interleukin-4 signaling pathway' added !
41735view02:39, 2 March 2011MaintBotRemoved redundant pathway information and comments
28141view23:56, 27 January 2009KhanspersChanged name
21061view11:30, 14 November 2008MaintBot[[Pathway:Rattus norvegicus:IL-4 NetPath 16]] moved to [[Pathway:WP182]]: Moved to stable identifier
8180view13:46, 7 January 2008MaintBot[[Pathway:Rat:IL-4 NetPath 16]] moved to [[Pathway:Rattus norvegicus:IL-4 NetPath 16]]: Renaming species
7710view16:11, 18 December 2007MaintBotfixed category names
7249view12:41, 4 November 2007MaintBotAdded categories to GPML
6561view22:20, 22 May 2007A.Pandeygpml file for [[Rat:IL-4_NetPath_16]]

External references

DataNodes

View all...
NameTypeDatabase referenceComment
Adrbk2GeneProduct25372 (Entrez Gene)
Akt1GeneProduct24185 (Entrez Gene)
Atf2GeneProduct81647 (Entrez Gene)
BadGeneProduct64639 (Entrez Gene)
Bcl2l1GeneProduct24888 (Entrez Gene)
CrebbpGeneProduct54244 (Entrez Gene)
Cxcr4GeneProduct60628 (Entrez Gene)
Dok2GeneProduct290361 (Entrez Gene)
Elk1GeneProduct314436 (Entrez Gene)
Ep300GeneProduct170915 (Entrez Gene)
Ets1GeneProduct24356 (Entrez Gene)
FynGeneProduct25150 (Entrez Gene)
Gene SymbolGeneProduct
Grb2GeneProduct81504 (Entrez Gene)
HIST2H3CGeneProduct (Entrez Gene)
Hmga1GeneProduct117062 (Entrez Gene)
Il13ra1GeneProduct252963 (Entrez Gene)
Il2rgGeneProduct140924 (Entrez Gene)
Il4GeneProduct287287 (Entrez Gene)
Il4raGeneProduct25084 (Entrez Gene)
Inpp5dGeneProduct54259 (Entrez Gene)
Irs1GeneProduct25467 (Entrez Gene)
Irs2GeneProduct29376 (Entrez Gene)
Jak1GeneProduct84598 (Entrez Gene)
Jak2GeneProduct24514 (Entrez Gene)
Jak3GeneProduct25326 (Entrez Gene)
Lck mappedGeneProduct313050 (Entrez Gene)
MAPK11GeneProduct (Entrez Gene)
Mapk1GeneProduct116590 (Entrez Gene)
Mapk14GeneProduct81649 (Entrez Gene)
Mapk3GeneProduct50689 (Entrez Gene)
NCF1GeneProduct (Entrez Gene)
Nfkb1GeneProduct81736 (Entrez Gene)
PIK3CAGeneProduct (Entrez Gene)
PawrGeneProduct64513 (Entrez Gene)
Pik3cdGeneProduct366508 (Entrez Gene)
Pik3r1GeneProduct25513 (Entrez Gene)
Pik3r2GeneProduct29741 (Entrez Gene)
Plcg1GeneProduct25738 (Entrez Gene)
PrkcdGeneProduct170538 (Entrez Gene)
PrkciGeneProduct84006 (Entrez Gene)
PrkcnGeneProduct313834 (Entrez Gene)
PrkczGeneProduct25522 (Entrez Gene)
Ptk2GeneProduct25614 (Entrez Gene)
Ptpn11GeneProduct25622 (Entrez Gene)
Ptpn6GeneProduct116689 (Entrez Gene)
RGD1561386GeneProduct500985 (Entrez Gene)
RGD1564385GeneProduct361597 (Entrez Gene)
RGD1564499GeneProduct498798 (Entrez Gene)
RGD1564914GeneProduct500616 (Entrez Gene)
Rasa1GeneProduct25676 (Entrez Gene)
RelaGeneProduct309165 (Entrez Gene)
Rps6kb1GeneProduct83840 (Entrez Gene)
Sfpi1GeneProduct366126 (Entrez Gene)
Shc1GeneProduct85385 (Entrez Gene)
Socs1GeneProduct252971 (Entrez Gene)
Socs3GeneProduct89829 (Entrez Gene)
Sos1GeneProduct313845 (Entrez Gene)
SrcGeneProduct83805 (Entrez Gene)
Stat1GeneProduct25124 (Entrez Gene)
Stat5aGeneProduct24918 (Entrez Gene)
Stat6GeneProduct362896 (Entrez Gene)
TYK2GeneProduct (Entrez Gene)

Annotated Interactions

No annotated interactions
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