RalA downstream regulated genes (Homo sapiens)
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Description
Using the KEGG database, combined with recent publication, the authors of the paper analyzed genes in downstream of RalA signaling pathways, including the Rac-family GTPase-activating protein RLIP (also known as RLIP76 and ralA binding protein 1 (RALBP1)), CDC42(cell division cycle 42), RAC1 (ras-related C3 botulinum toxin substrate 1), RAC2, RAC3, the Y-box transcription factor ZO-1-associated nucleic acidbinding protein (ZONAB, also known as cold shock domain protein A (CSDA)), and two subunits of the exocyst complex, SEC5 (also known as exocyst complex component 2 (EXOC2)) and EXO84 (also known as EXOC8), which are involved in regulating cell proliferation, apoptosis and migration
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Ontology Terms
Saving...Bibliography
- Fei J, Li Y, Zhu X, Luo X; ''miR-181a post-transcriptionally downregulates oncogenic RalA and contributes to growth inhibition and apoptosis in chronic myelogenous leukemia (CML).''; PLoS One, 2012 PubMed Europe PMC Scholia
History
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External references
DataNodes
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| Name | Type | Database reference | Comment |
|---|---|---|---|
| CDC42 | GeneProduct | 998 (Entrez Gene)  | |
| EXOC84 | GeneProduct | 149371 (Entrez Gene) | |
| RAC1 | GeneProduct | 5879 (Entrez Gene) | |
| RAC2 | GeneProduct | 5880 (Entrez Gene) | |
| RAC3 | GeneProduct | 5881 (Entrez Gene) | |
| RALBP1 | GeneProduct | 10928 (Entrez Gene) | |
| RAS | GeneProduct | ||
| RalA | GeneProduct | 5898 (Entrez Gene) | |
| SEC5 | GeneProduct | 55770 (Entrez Gene) | |
| ZONAB | GeneProduct | 8531 (Entrez Gene) |
Annotated Interactions
No annotated interactions
