Electron transport chain (Canis familiaris)

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IntermembraneSpaceComplex IVComplex IINADH-UbiquinoneOxidoreductaseComplex IIIF1 ComplexComplex VATP Synthase F0 ComplexComplex IC subunitbinds ATP Synthase betaAdenine NucleotideTranslocatorCytochrome COxidaseStalkUbiquinol-Cytochrome CReductaseAssemblySuccinate-UbiquinoneOxidoreductaseMatrixUncoupling ProteinNDUFS3COX1ATP6NDUFB3SURF1ND5NDUFV3NDUFB4H+ATP5G3NDUFC1SLC25A5NDUFB7NDUFA5NDUFA4NDUFB9H+ATP5LNDUFS5ND4NDUFB10SLC25A14UCP2ATP5G1FADH2NDUFAB1SDHBATP5A1NDUFS2NDUFV1NDUFS6NDUFB6LOC479623H+ATP5ELOC477944e-NDUFA7COX2LOC475739ATPIF1SDHCNDUFA8COX5BNDUFA3ATP5SUbiquinoneLOC608455LOC608530O2NDUFB1NDUFA12ATP5G2H+COX3LOC612614ATP5DND3ATPNDUFB2NDUFB8NDUFB5LOC486347FADCOX17SuccinateCOX5AATP5C1NDUFA1H+NDUFS4LOC477508H2OLOC611134ND4LND2ATP5BLOC476040LOC479438NDUFA9ATP5ONDUFV2e-COX7BNDUFA2LOC609990LOC611791LOC476503COX6CLOC609555LOC609744LOC477792NDUFS7LOC612644NDUFS8SDHASCO1LOC479815ATP5F1ATP5He-LOC479780UCP3SLC25A27NDUFC2NDUFA10H+ATP5JH+NADHCOX7A3Cytochrome CNDUFA6ND1SLC25A4ATP8TCA CycleND6ATP5J2NDUFS1CYTBNAD+SLC25A6UCP1ATP5I


Description

An electron transport chain(ETC) couples a chemical reaction between an electron donor (such as NADH) and an electron acceptor (such as O2) to the transfer of H+ ions across a membrane, through a set of mediating biochemical reactions. These H+ ions are used to produce adenosine triphosphate (ATP), the main energy intermediate in living organisms, as they move back across the membrane.

In mitochondria, it is the conversion of oxygen to water, NADH to NAD+ and succinate to fumarate that drives the transfer of H+ ions.

Source: Wikipedia (wikipedia:Electron_transport_chain)

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP111(r20917) with a 68% conversion rate.

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Ontology Terms

 

Bibliography

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History

View all...
CompareRevisionActionTimeUserComment
122664view05:37, 28 April 2022EgonwMade a pathway clickable
117447view10:52, 21 May 2021EweitzModified title
106043view11:56, 16 August 2019MaintBotHMDB identifier normalization
97067view15:40, 26 April 2018AMTanConverted line to graphical line
95789view14:40, 19 January 2018MkutmonHomology conversion update
79219view13:36, 15 March 2015EgonwReplaced the HMDB H2 identifier with H+ from ChEBI.
71488view19:19, 17 October 2013MaintBotAutomated update of data sources
68594view23:20, 5 July 2013MaintBotUpdated to 2013 gpml schema
62728view03:18, 2 May 2013MaintBotUpdated UniProt data source
58280view18:38, 11 February 2013MaintBotOntology Term : 'electron transport chain pathway' added !
58252view23:01, 10 February 2013EgonwRemoved data source where no ID was given.
40754view21:54, 1 March 2011MaintBotRemoved redundant pathway information and comments
38667view14:06, 23 September 2010FerryJagersLinked TCA Cycle
35265view20:21, 11 February 2010AlexanderPicoModified description
34027view18:47, 9 December 2009MaintBotAutomatic update of empty xrefs
32555view13:07, 17 August 2009MaintBotFixed text labels
32237view12:51, 15 August 2009MaintBotFixed text labels
31745view12:01, 14 August 2009MaintBotFixed group labels
31253view19:52, 13 August 2009MaintBotFixed text labels
30688view22:45, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ATP5A1GeneProduct480149 (Entrez Gene)
ATP5BGeneProduct403669 (Entrez Gene)
ATP5C1GeneProduct478009 (Entrez Gene)
ATP5DGeneProduct476756 (Entrez Gene)
ATP5EGeneProduct
ATP5F1GeneProduct479901 (Entrez Gene)
ATP5G1GeneProduct491061 (Entrez Gene)
ATP5G2GeneProduct477595 (Entrez Gene)
ATP5G3GeneProduct478807 (Entrez Gene)
ATP5HGeneProduct
ATP5IGeneProduct
ATP5J2GeneProduct
ATP5JGeneProduct478393 (Entrez Gene)
ATP5LGeneProduct
ATP5OGeneProduct
ATP5SGeneProduct490683 (Entrez Gene)
ATP6GeneProduct804488 (Entrez Gene)
ATP8GeneProduct804487 (Entrez Gene)
ATPMetaboliteC00002 (Kegg Compound)
ATPIF1GeneProduct478165 (Entrez Gene)
COX17GeneProduct503668 (Entrez Gene)
COX1GeneProduct804478 (Entrez Gene)
COX2GeneProduct804479 (Entrez Gene)
COX3GeneProduct804480 (Entrez Gene)
COX5AGeneProduct
COX5BGeneProduct474567 (Entrez Gene)
COX6CGeneProduct
COX7A3GeneProduct
COX7BGeneProduct
CYTBGeneProduct804486 (Entrez Gene)
Cytochrome CMetaboliteC00524 (Kegg Compound)
FADMetaboliteC00016 (Kegg Compound)
FADH2MetaboliteC01352 (Kegg Compound)
H+MetaboliteHMDB01362 (HMDB)
H2OMetaboliteHMDB02111 (HMDB)
LOC475739GeneProduct475739 (Entrez Gene)
LOC476040GeneProduct476040 (Entrez Gene)
LOC476503GeneProduct476503 (Entrez Gene)
LOC477508GeneProduct477508 (Entrez Gene)
LOC477792GeneProduct477792 (Entrez Gene)
LOC477944GeneProduct477944 (Entrez Gene)
LOC479438GeneProduct479438 (Entrez Gene)
LOC479623GeneProduct479623 (Entrez Gene)
LOC479780GeneProduct479780 (Entrez Gene)
LOC479815GeneProduct479815 (Entrez Gene)
LOC486347GeneProduct486347 (Entrez Gene)
LOC608455GeneProduct608455 (Entrez Gene)
LOC608530GeneProduct608530 (Entrez Gene)
LOC609555GeneProduct609555 (Entrez Gene)
LOC609744GeneProduct609744 (Entrez Gene)
LOC609990GeneProduct609990 (Entrez Gene)
LOC611134GeneProduct611134 (Entrez Gene)
LOC611791GeneProduct611791 (Entrez Gene)
LOC612614GeneProduct612614 (Entrez Gene)
LOC612644GeneProduct612644 (Entrez Gene)
NAD+MetaboliteC00003 (Kegg Compound)
NADHMetaboliteC00004 (Kegg Compound)
ND1GeneProduct804476 (Entrez Gene)
ND2GeneProduct804477 (Entrez Gene)
ND3GeneProduct804481 (Entrez Gene)
ND4GeneProduct804483 (Entrez Gene)
ND4LGeneProduct804482 (Entrez Gene)
ND5GeneProduct804484 (Entrez Gene)
ND6GeneProduct804485 (Entrez Gene)
NDUFA1GeneProduct
NDUFA10GeneProduct608244 (Entrez Gene)
NDUFA12GeneProduct475428 (Entrez Gene)
NDUFA2GeneProduct478032 (Entrez Gene)
NDUFA3GeneProduct611480 (Entrez Gene)
NDUFA4GeneProduct477682 (Entrez Gene)
NDUFA5GeneProduct475214 (Entrez Gene)
NDUFA6GeneProduct474483 (Entrez Gene)
NDUFA7GeneProduct476722 (Entrez Gene)
NDUFA8GeneProduct480741 (Entrez Gene)
NDUFA9GeneProduct477718 (Entrez Gene)
NDUFAB1GeneProduct479805 (Entrez Gene)
NDUFB1GeneProduct
NDUFB10GeneProduct479887 (Entrez Gene)
NDUFB2GeneProduct
NDUFB3GeneProduct478869 (Entrez Gene)
NDUFB4GeneProduct478577 (Entrez Gene)
NDUFB5GeneProduct
NDUFB6GeneProduct
NDUFB7GeneProduct476686 (Entrez Gene)
NDUFB8GeneProduct477798 (Entrez Gene)
NDUFB9GeneProduct475094 (Entrez Gene)
NDUFC1GeneProduct607943 (Entrez Gene)
NDUFC2GeneProduct476794 (Entrez Gene)
NDUFS1GeneProduct478880 (Entrez Gene)
NDUFS2GeneProduct478981 (Entrez Gene)
NDUFS3GeneProduct475978 (Entrez Gene)
NDUFS4GeneProduct479335 (Entrez Gene)
NDUFS5GeneProduct475322 (Entrez Gene)
NDUFS6GeneProduct478629 (Entrez Gene)
NDUFS7GeneProduct476754 (Entrez Gene)
NDUFS8GeneProduct
NDUFV1GeneProduct476004 (Entrez Gene)
NDUFV2GeneProduct480204 (Entrez Gene)
NDUFV3GeneProduct
O2MetaboliteHMDB01377 (HMDB)
SCO1GeneProduct489505 (Entrez Gene)
SDHAGeneProduct478634 (Entrez Gene)
SDHBGeneProduct608210 (Entrez Gene)
SDHCGeneProduct478983 (Entrez Gene)
SLC25A14GeneProduct612910 (Entrez Gene)
SLC25A27GeneProduct609887 (Entrez Gene)
SLC25A4GeneProduct475630 (Entrez Gene)
SLC25A5GeneProduct492093 (Entrez Gene)
SLC25A6GeneProduct480830 (Entrez Gene)
SURF1GeneProduct480681 (Entrez Gene)
SuccinateMetaboliteC00042 (Kegg Compound)
TCA CyclePathwayWP1115 (WikiPathways)
UCP1GeneProduct403574 (Entrez Gene)
UCP2GeneProduct403576 (Entrez Gene)
UCP3GeneProduct403575 (Entrez Gene)
UbiquinoneMetabolite
e-MetaboliteC05359 (Kegg Compound)

Annotated Interactions

No annotated interactions
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