Methylation pathways (Bos taurus)

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1, 2SAM synthesis (co-substrate)S-methylationO-methylationN-methylationMETK1_BOVINS-AdenosylhomocysteineS-AdenosylhomocysteineS-AdenosylmethionineMAT2B_BOVINIPI00695153.3S-methylated substrateNP_001094601.1ATPPhosphateS-AdenosylhomocysteineO-methylated substrateTPMT_BOVINPNMT_BOVINSubstrateN-methylated substrateS-AdenosylmethioninePhosphateS-AdenosylmethionineCOMT_BOVINNNMTL-MethionineHNMT_BOVIN


Description

No description

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP704(r30265) with a 88% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Testa B, Kramer SD; ''The biochemistry of drug metabolism--an introduction: part 4. reactions of conjugation and their enzymes.''; Chem Biodivers, 2008 PubMed Europe PMC Scholia
  2. Weinshilboum RM; ''Pharmacogenomics: catechol O-methyltransferase to thiopurine S-methyltransferase.''; Cell Mol Neurobiol, 2006 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
117555view11:18, 21 May 2021EweitzModified title
105962view11:49, 16 August 2019MaintBotHMDB identifier normalization
80687view15:22, 30 June 2015Mkutmonhomology conversion
70172view00:40, 13 July 2013AlexanderPicoModified title
63373view23:06, 9 May 2013MaintBotUpdated to 2013 gpml schema
58821view23:19, 20 February 2013MaintBotUpdated Ensembl and UniProt data source
40545view19:31, 1 March 2011MaintBotRemoved redundant pathway information and comments
33633view10:05, 1 December 2009MaintBotRemoved group label
30561view22:03, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ATPMetaboliteHMDB00538 (HMDB)
COMT_BOVINGeneProductENSBTAG00000019516 (Ensembl)
HNMT_BOVINGeneProductENSBTAG00000014432 (Ensembl)
IPI00695153.3GeneProductENSBTAG00000001448 (Ensembl)
L-MethionineMetaboliteHMDB00696 (HMDB)
MAT2B_BOVINGeneProductENSBTAG00000012350 (Ensembl)
METK1_BOVINGeneProductENSBTAG00000005963 (Ensembl)
N-methylated substrateMetabolite
NNMTGeneProduct
NP_001094601.1GeneProductENSBTAG00000020873 (Ensembl)
O-methylated substrateMetabolite
PNMT_BOVINGeneProductENSBTAG00000011731 (Ensembl)
PhosphateMetaboliteHMDB01429 (HMDB)
S-AdenosylhomocysteineMetaboliteHMDB00939 (HMDB)
S-AdenosylmethionineMetaboliteHMDB01185 (HMDB)
S-methylated substrateMetabolite
SubstrateMetabolite
TPMT_BOVINGeneProductENSBTAG00000019300 (Ensembl)

Annotated Interactions

No annotated interactions
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