Homologous recombination (Drosophila melanogaster)

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1Pol-deltaSister chromatidStrand invasionPol-deltaPol-deltagamma radiation / genotoxic drugsMRN complexDamaged chromatidokrspn-Aokrspn-AnbsBRCA2POLD4mre11spn-ARAD52DNApol-deltaRAD52rad50tefuPOLD3spn-ARPA1 ?BRCA2BRCA2CG12018RPA1 ?RPA1 ?RAD52tefuBRCA2RPA1 ?


Description

Homologous recombination, also known as general recombination, is a type of genetic recombination in which nucleotide sequences are exchanged between two similar or identical strands of DNA. Source: Wikipedia

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP186(r29610) with a 50% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. Bruce Alberts, Dennis Bray, Julian Lewis, Martin Raff, Keith Roberts, James D. Watson; ''Molecular Biology of the Cell, 4th edition''; http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=mboc4&part=A747#A845, 2002

History

View all...
CompareRevisionActionTimeUserComment
116934view09:59, 16 May 2021EweitzModified title
79391view20:07, 21 March 2015KhanspersModified title
79390view20:07, 21 March 2015Khanspersupdate schema
79389view20:07, 21 March 2015KhanspersReverted to version '10:40, 26 June 2013' by Khanspers
70182view01:30, 13 July 2013AlexanderPicoModified title
68706view21:31, 6 July 2013MaintBotUpdated to 2013 gpml schema
67343view10:40, 26 June 2013Christine ChichesterOntology Term : 'homologous recombination pathway of double-strand break repair' added !
58863view00:18, 21 February 2013MaintBotUpdated Ensembl and UniProt data source
40874view22:33, 1 March 2011MaintBotRemoved redundant pathway information and comments
36290view23:17, 17 March 2010KhanspersModified categories
35584view15:27, 12 February 2010ThomasModified description
35572view15:21, 12 February 2010Thomasadded literature
31814view12:22, 14 August 2009MaintBotFixed group labels
30774view23:22, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
BRCA2GeneProduct
CG12018GeneProductFBgn0027903 (Ensembl)
DNApol-deltaGeneProductFBgn0012066 (Ensembl)
POLD3GeneProduct
POLD4GeneProduct
RAD52GeneProduct
RPA1 ?GeneProduct
mre11GeneProductFBgn0020270 (Ensembl)
nbsGeneProductFBgn0086349 (Ensembl)
okrGeneProductFBgn0002989 (Ensembl)
rad50GeneProductFBgn0034728 (Ensembl)
spn-AGeneProductFBgn0003479 (Ensembl)
tefuGeneProductFBgn0045035 (Ensembl)

Annotated Interactions

No annotated interactions
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