NAD biosynthesis II from tryptophan (Homo sapiens)
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1-28
spontaneous
Carbon dioxide
L-Glutamic acid
Pyrophosphate
TDO2
N'-Formylkynurenine
NADP
Phosphoribosyl
pyrophosphate
Adenosine
triphosphate
Quinolinic acid
AFMID
L-Alanine
Water
Adenosine
monophosphate
L-Kynurenine
NMNAT1
NADPH
Adenosine
triphosphate
2-Amino-3-carboxymuconic
acid semialdehyde
L-3-Hydroxykynurenine
Pyrophosphate
L-Glutamine
Hydrogen Ion
Oxygen
Nicotinic acid
adenine dinucleotide
Nicotinic acid
mononucleotide
NADSYN1
Formic acid
L-Tryptophan
Water
KYNU
Water
QPRT
NAD
HAAO
KMO
pyrophosphate
3-Hydroxyanthranilic acid
Hydrogen Ion
Water
Hydrogen Ion
Hydrogen Ion
Hydrogen Ion
Hydrogen Ion
Oxygen
Hydrogen Ion
Water
Hydrogen Ion
Hydrogen Ion
Hydrogen Ion
Oxygen
Hydrogen Ion
Hydrogen Ion
Description
No description
Comments
GenMAPP notes
http://biocyc.org/META/new-image?type=PATHWAY&object=NADSYN-PWY&detail-level=3&ENZORG=TAX-9606
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Revision
Action
Time
User
Comment
134903
view
01:13, 29 July 2024
Eweitz
Modified title
117161
view
09:47, 18 May 2021
Eweitz
Modified title
108352
view
09:25, 11 December 2019
L Dupuis
Connected unconnected lines
106715
view
13:15, 17 September 2019
MaintBot
HMDB identifier normalization
102307
view
21:04, 17 December 2018
Khanspers
Modified description
102306
view
21:01, 17 December 2018
Khanspers
removed GenMAPP comment
70025
view
01:53, 12 July 2013
AlexanderPico
Modified title
69051
view
17:55, 8 July 2013
Egonw
Marked 'pyrophosphate' with a CAS number as metabolite.
62867
view
10:33, 3 May 2013
Cizar
Modified description
62270
view
22:24, 26 April 2013
AlexanderPico
Ontology Term : 'NAD biosynthetic pathway' added !
62269
view
22:24, 26 April 2013
AlexanderPico
Modified categories
61951
view
07:29, 22 April 2013
Cizar
Grouped metabolites and aligned them
61804
view
10:55, 19 April 2013
Cizar
Modified description
61794
view
09:50, 19 April 2013
Cizar
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
2-Amino-3-carboxymuconic acid semialdehyde
Metabolite
HMDB01330 (HMDB)
3-Hydroxyanthranilic acid
Metabolite
HMDB01476 (HMDB)
AFMID
GeneProduct
ENSG00000183077 (Ensembl)
Adenosine monophosphate
Metabolite
HMDB00045 (HMDB)
Adenosine triphosphate
Metabolite
HMDB00538 (HMDB)
Carbon dioxide
Metabolite
HMDB01967 (HMDB)
Formic acid
Metabolite
HMDB00142 (HMDB)
HAAO
GeneProduct
ENSG00000162882 (Ensembl)
Hydrogen Ion
Metabolite
HMDB59597 (HMDB)
KMO
GeneProduct
ENSG00000117009 (Ensembl)
KYNU
GeneProduct
ENSG00000115919 (Ensembl)
L-3-Hydroxykynurenine
Metabolite
HMDB11631 (HMDB)
L-Alanine
Metabolite
HMDB00161 (HMDB)
L-Glutamic acid
Metabolite
HMDB00148 (HMDB)
L-Glutamine
Metabolite
HMDB00641 (HMDB)
L-Kynurenine
Metabolite
HMDB00684 (HMDB)
L-Tryptophan
Metabolite
HMDB00929 (HMDB)
N'-Formylkynurenine
Metabolite
HMDB01200 (HMDB)
NAD
Metabolite
HMDB00902 (HMDB)
NADPH
Metabolite
HMDB00221 (HMDB)
NADP
Metabolite
HMDB00217 (HMDB)
NADSYN1
GeneProduct
ENSG00000172890 (Ensembl)
NMNAT1
GeneProduct
ENSG00000173614 (Ensembl)
Nicotinic acid adenine dinucleotide
Metabolite
HMDB01179 (HMDB)
Nicotinic acid mononucleotide
Metabolite
HMDB01132 (HMDB)
Oxygen
Metabolite
HMDB01377 (HMDB)
Phosphoribosyl pyrophosphate
Metabolite
HMDB00280 (HMDB)
Pyrophosphate
Metabolite
HMDB00250 (HMDB)
QPRT
GeneProduct
ENSG00000103485 (Ensembl)
Quinolinic acid
Metabolite
HMDB00232 (HMDB)
TDO2
GeneProduct
ENSG00000151790 (Ensembl)
Water
Metabolite
HMDB02111 (HMDB)
pyrophosphate
2466-09-3 (CAS)
Annotated Interactions
No annotated interactions
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