NAD biosynthesis I from aspartate (Escherichia coli)

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nadBAmmoniaCarbon dioxideNADAdenosinemonophosphateHydrogen peroxideNicotinic acidadeninedinucleotidePyrophosphateQuinolinic acidL-Aspartic acidNicotinic acidmononucleotidenadCnadE:NH3-dependentAdenosinetriphosphateL-Glutamic acidnadAOxygenHydrogen IonPhosphoribosylpyrophosphateDihydroxyacetonephosphateWaterPhosphateIminoaspartic acidL-GlutaminenadDWaterHydrogen IonHydrogen IonHydrogen IonPyrophosphateWaterAdenosinetriphosphateHydrogen IonPyrophosphateAdenosinemonophosphatePyrophosphateAdenosinetriphosphatenadE:glutamine-dependent


Description

This is a general pathway for NAD biosynthesis in prokaryotes, where aspertate is eventually converted into NAD. Though through recent studies it seems that NAD biosynthesis through tryptophan also occurs in some prokaryotes.

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Bibliography

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History

View all...
CompareRevisionActionTimeUserComment
117436view10:51, 21 May 2021EweitzModified title
106098view12:00, 16 August 2019MaintBotHMDB identifier normalization
80402view14:16, 15 June 2015Mkutmonupdated ensembl identifiers
62863view10:25, 3 May 2013CizarModified description
62272view22:25, 26 April 2013AlexanderPicoOntology Term : 'NAD biosynthetic pathway' added !
62271view22:25, 26 April 2013AlexanderPicoModified categories
61950view07:19, 22 April 2013CizarAligned data nodes
61949view07:15, 22 April 2013CizarGrouped metabolites
61806view11:08, 19 April 2013Cizaradded references
61805view11:00, 19 April 2013CizarModified description
61793view09:49, 19 April 2013CizarNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
Adenosine monophosphateMetaboliteHMDB00045 (HMDB)
Adenosine triphosphateMetaboliteHMDB00538 (HMDB)
AmmoniaMetaboliteHMDB00051 (HMDB)
Carbon dioxideMetaboliteHMDB01967 (HMDB)
Dihydroxyacetone phosphateMetaboliteHMDB01473 (HMDB)
Hydrogen IonMetaboliteHMDB59597 (HMDB)
Hydrogen peroxideMetaboliteHMDB03125 (HMDB)
Iminoaspartic acidMetaboliteHMDB01131 (HMDB)
L-Aspartic acidMetaboliteHMDB00191 (HMDB)
L-Glutamic acidMetaboliteHMDB00148 (HMDB)
L-GlutamineMetaboliteHMDB00641 (HMDB)
NADMetaboliteHMDB00902 (HMDB)
Nicotinic acid

adenine

dinucleotide
MetaboliteHMDB01179 (HMDB)
Nicotinic acid mononucleotideMetaboliteHMDB01132 (HMDB)
OxygenMetaboliteHMDB01377 (HMDB)
PhosphateMetaboliteHMDB01429 (HMDB)
Phosphoribosyl pyrophosphateMetaboliteHMDB00280 (HMDB)
PyrophosphateMetaboliteHMDB00250 (HMDB)
Quinolinic acidMetaboliteHMDB00232 (HMDB)
WaterMetaboliteHMDB02111 (HMDB)
nadAGeneProductEBESCG00000002693 (Ensembl)
nadBGeneProductEBESCG00000001401 (Ensembl)
nadCGeneProductEBESCG00000000232 (Ensembl)
nadDGeneProductEBESCG00000001808 (Ensembl)
nadE: NH3-dependentGeneProductEBESCG00000001347 (Ensembl)
nadE:

glutamine-

dependent
GeneProductEBESCG00000001347 (Ensembl)

Annotated Interactions

No annotated interactions

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