GPCRs, class A rhodopsin-like (Bos taurus)

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ORPHLGR like (hormone receptors)CannabisEndothelinOlfactoryOrexin & neuropeptide FFCCKAPJ likeClass A OrphansHormone proteinFollicle stimulating hormoneThrombinNeuropeptide YInterleukin-8Adrenomedullin (G10D)BombesinOpioid(Rhod)opsinRhodopsin VertebrateFmet-leu-pheRhodopsin OtherChemokineC-C ChemokineGP40 likeSREBOther Chemokine ReceptorsNeuropeptide Y / peptide YYChemokine receptor-likePurinoceptorsNucleotide-likeAdenosineC-X-C ChemokineAdrenoceptorsAlpha AdrenoceptorsClass A Orphan/otherPlatelet ADP & KI01 receptorsBeta AdrenoceptorsOlfactory OtherThyrotropin-releasing hormone and SecretagogueGPR45 likeMelatoninLutropin-choriogonadotropic hormoneC5a anaphylatoxinPurinoceptor type YMelanocortinPlatelet activating factorBONZO receptors (CXC6R)Mas proto-oncogeneNeuromedin UAmineAcetylcholine (muscarinic)SomatostatinVasopressin-likeOR1A2MAS1OR2A4HTR7NPFFR2GPR65OR11A1HTR1ENPY2RSSTR3LPAR4GPR75OR1A1CXCR7OR2AG1GPR22GPR12HTR1DOR3A2CCR8OPN1LWDRD4GPR35CHRM3GPR109BOPN3GPR174OPN4FFAR1F2RL3GRPRRRHP2RY14SSTR1GPR50P2RY1LOC528374PTGER2FSHRCHRM1ADRA1BGPR52P2RY13F2RL2ADORA3XCR1OXTRADRB3HRH3CHRM5OR5F1CNR2LOC782431GPR27GPR37L1LOC538946SUCNR1ADRA2ABDKRB1DRD3GPR37ADRA2CLHCGREDNRBLOC788289ADORA2BP2RY5NPBWR1OR10H2ADORA2AGPERDRD2ADRA2BLOC539623CNR1IL8RAMCHR1MC3RNPY6RP2RY11BradykininCCR10HTR5AGPR83F2RL1GPR161HTR2ANPFFR1TBXA2RAVPR1BF2RCHRM2GPR45OR2F1SerotoninOR10H1LOC513732OR10J1DRD5P2RY10HTR1BGPR87GPR63BRS3LOC540255OR2H2LOC504498GPR92OR10H3OR3A3RHOHRH2CXCR3NPY1RCCRL2NMBRLOC521903OR10A5GPR17P2RY12FFAR2CXCR4LOC539185MC1RGPR171OR3A4DRD1PTGIRCCR9MAS1LCCR3GPR32GPR77PTGER3OR7A5GPR3NPY5RADORA1OR2B2OR1E2OR1C1NTSR1LOC507573MC4RAVPR2MC2ROR7C1PTGFRLOC616938GHSROPRK1ADRA1AMTNR1AHTR2BCHRM4FFAR3LOC509170GPR4CMKLR1RgrNTSR2GPR42GALR3LOC532476LTB4RCCKARCXCR5Q9UDD9LOC514760OR2J1PRLHROR2N1PLOC509916AGTR2GPR25OR1D4GALR1LOC618597LOC532454OPN1SWHTR6OR2H1CCKBRPTAFRFPRL1OPRL1GPR18GPR6PTGER4ProstaglandinGPR34CYSLTR1CCR7OR2B3GALR2CCRL1HTR1AADRB2GPR21MC5RLOC540205OPRM1CCR6HCRTR2LOC524872OPRD1CCR2BDKRB2GPR20HistamineGPR15CX3CR1CCR5FPRL2NMUR2OR2F2APLNRPTGER1GPR44ADRA1DGPR85TRHRAGTR1GPR39GPR1MTNR1BCCR1IL8RBLOC538864CYSLTR2HTR4CCR4DopamineHRH1AVPR1AGPR68MLNROR1F1C3AR1P2RY2SSTR5P2RY6LOC505191PPYR1FPR1CCBP2GPR31LOC617571SSTR2OPN1MWEDNRAGPR81OR1D2PTGDRP2RY4Angiotensin IINMUR1GPR19LOC785397ADRB1HTR1FLOC784712SSTR4GPR8LOC528930GPR173HCRTR1HTR2C


Description

No description

Comments

GenMAPP notes 
This MAPP was created using the GPCRDB (Horn et al., 1998), http://www.cmbi.kun.nl/7tm/. The groupings are based on the GPCR phylogenetic tree available from the GPCRDB and the training sets used by Karchin et al. (Bioinformatics, 2002, pg. 147-159). The labels indicate children and grandchildren of the various classes of GPCRs as described by these references.
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP455(r21638) with a 74% conversion rate.

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Ontology Terms

 

Bibliography

  1. Karchin R, Karplus K, Haussler D; ''Classifying G-protein coupled receptors with support vector machines.''; Bioinformatics, 2002 PubMed Europe PMC Scholia
  2. Horn F, Weare J, Beukers MW, Hأ¶rsch S, Bairoch A, Chen W, Edvardsen O, Campagne F, Vriend G; ''GPCRDB: an information system for G protein-coupled receptors.''; Nucleic Acids Res, 1998 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
117525view11:09, 21 May 2021EweitzModified title
105963view11:49, 16 August 2019MaintBotHMDB identifier normalization
80837view15:28, 30 June 2015Mkutmonhomology conversion
71431view19:03, 17 October 2013MaintBotAutomated update of data sources
63465view17:19, 10 May 2013MaintBotUpdated to 2013 gpml schema
62712view23:20, 1 May 2013MaintBotUpdated UniProt data source
40600view19:34, 1 March 2011MaintBotRemoved redundant pathway information and comments
33837view00:31, 9 December 2009MaintBotAutomatic update of empty xrefs
32526view12:58, 17 August 2009MaintBotFixed text labels
32213view12:43, 15 August 2009MaintBotFixed text labels
31705view11:51, 14 August 2009MaintBotFixed group labels
31224view19:42, 13 August 2009MaintBotFixed text labels
30641view22:30, 29 July 2009MaintBotNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
ADORA1GeneProduct282133 (Entrez Gene)
ADORA2AGeneProduct617828 (Entrez Gene)
ADORA2BGeneProduct529760 (Entrez Gene)
ADORA3GeneProduct780806 (Entrez Gene)
ADRA1AGeneProduct282134 (Entrez Gene)
ADRA1BGeneProduct407140 (Entrez Gene)
ADRA1DGeneProduct539543 (Entrez Gene)
ADRA2AGeneProduct282135 (Entrez Gene)
ADRA2BGeneProduct516422 (Entrez Gene)
ADRA2CGeneProduct407139 (Entrez Gene)
ADRB1GeneProduct281604 (Entrez Gene)
ADRB2GeneProduct281605 (Entrez Gene)
ADRB3GeneProduct281606 (Entrez Gene)
AGTR1GeneProduct281607 (Entrez Gene)
AGTR2GeneProduct407157 (Entrez Gene)
APLNRGeneProduct615435 (Entrez Gene)
AVPR1AGeneProduct538439 (Entrez Gene)
AVPR1BGeneProduct282861 (Entrez Gene)
AVPR2GeneProduct281642 (Entrez Gene)
Angiotensin IIMetaboliteHMDB01035 (HMDB)
BDKRB1GeneProduct532119 (Entrez Gene)
BDKRB2GeneProduct538896 (Entrez Gene)
BRS3GeneProduct539011 (Entrez Gene)
BradykininMetabolite
C3AR1GeneProduct540702 (Entrez Gene)
CCBP2GeneProduct512583 (Entrez Gene)
CCKARGeneProduct506207 (Entrez Gene)
CCKBRGeneProduct281665 (Entrez Gene)
CCR10GeneProduct539108 (Entrez Gene)
CCR1GeneProduct407771 (Entrez Gene)
CCR2GeneProduct539002 (Entrez Gene)
CCR3GeneProduct408018 (Entrez Gene)
CCR4GeneProduct408019 (Entrez Gene)
CCR5GeneProduct497017 (Entrez Gene)
CCR6GeneProduct519716 (Entrez Gene)
CCR7GeneProduct510668 (Entrez Gene)
CCR8GeneProduct407772 (Entrez Gene)
CCR9GeneProduct530951 (Entrez Gene)
CCRL1GeneProduct281672 (Entrez Gene)
CCRL2GeneProduct515976 (Entrez Gene)
CHRM1GeneProduct281684 (Entrez Gene)
CHRM2GeneProduct522170 (Entrez Gene)
CHRM3GeneProduct281685 (Entrez Gene)
CHRM4GeneProduct512928 (Entrez Gene)
CHRM5GeneProduct281686 (Entrez Gene)
CMKLR1GeneProduct615411 (Entrez Gene)
CNR1GeneProduct281087 (Entrez Gene)
CNR2GeneProduct539769 (Entrez Gene)
CX3CR1GeneProduct100124525 (Entrez Gene)
CXCR3GeneProduct497018 (Entrez Gene)
CXCR4GeneProduct281736 (Entrez Gene)
CXCR5GeneProduct497021 (Entrez Gene)
CXCR7GeneProduct509585 (Entrez Gene)
CYSLTR1GeneProduct782045 (Entrez Gene)
CYSLTR2GeneProduct540387 (Entrez Gene)
DRD1GeneProduct281125 (Entrez Gene)
DRD2GeneProduct281126 (Entrez Gene)
DRD3GeneProduct537043 (Entrez Gene)
DRD4GeneProduct
DRD5GeneProduct526221 (Entrez Gene)
DopamineMetabolite
EDNRAGeneProduct281749 (Entrez Gene)
EDNRBGeneProduct281750 (Entrez Gene)
F2RGeneProduct526585 (Entrez Gene)
F2RL1GeneProduct526525 (Entrez Gene)
F2RL2GeneProduct512581 (Entrez Gene)
F2RL3GeneProduct538963 (Entrez Gene)
FFAR1GeneProduct618180 (Entrez Gene)
FFAR2GeneProduct522431 (Entrez Gene)
FFAR3GeneProduct527517 (Entrez Gene)
FPR1GeneProduct
FPRL1GeneProduct
FPRL2GeneProduct
FSHRGeneProduct281172 (Entrez Gene)
GALR1GeneProduct539429 (Entrez Gene)
GALR2GeneProduct618629 (Entrez Gene)
GALR3GeneProduct788463 (Entrez Gene)
GHSRGeneProduct514203 (Entrez Gene)
GPERGeneProduct527831 (Entrez Gene)
GPR109BGeneProduct
GPR12GeneProduct522747 (Entrez Gene)
GPR1GeneProduct509707 (Entrez Gene)
GPR15GeneProduct538740 (Entrez Gene)
GPR161GeneProduct768006 (Entrez Gene)
GPR171GeneProduct767929 (Entrez Gene)
GPR173GeneProduct515148 (Entrez Gene)
GPR174GeneProduct781056 (Entrez Gene)
GPR17GeneProduct782442 (Entrez Gene)
GPR18GeneProduct540038 (Entrez Gene)
GPR19GeneProduct540647 (Entrez Gene)
GPR20GeneProduct515695 (Entrez Gene)
GPR21GeneProduct519193 (Entrez Gene)
GPR22GeneProduct783685 (Entrez Gene)
GPR25GeneProduct
GPR27GeneProduct
GPR31GeneProduct617303 (Entrez Gene)
GPR32GeneProduct
GPR34GeneProduct505292 (Entrez Gene)
GPR3GeneProduct540687 (Entrez Gene)
GPR35GeneProduct505056 (Entrez Gene)
GPR37GeneProduct532626 (Entrez Gene)
GPR37L1GeneProduct527572 (Entrez Gene)
GPR39GeneProduct100139476 (Entrez Gene)
GPR42GeneProduct
GPR44GeneProduct337885 (Entrez Gene)
GPR4GeneProduct512876 (Entrez Gene)
GPR45GeneProduct510657 (Entrez Gene)
GPR50GeneProduct530065 (Entrez Gene)
GPR52GeneProduct506159 (Entrez Gene)
GPR63GeneProduct517696 (Entrez Gene)
GPR6GeneProduct506661 (Entrez Gene)
GPR65GeneProduct788507 (Entrez Gene)
GPR68GeneProduct281799 (Entrez Gene)
GPR75GeneProduct539470 (Entrez Gene)
GPR77GeneProduct522144 (Entrez Gene)
GPR8GeneProduct
GPR81GeneProduct538759 (Entrez Gene)
GPR83GeneProduct541301 (Entrez Gene)
GPR85GeneProduct504208 (Entrez Gene)
GPR87GeneProduct785030 (Entrez Gene)
GPR92GeneProduct782992 (Entrez Gene)
GRPRGeneProduct532784 (Entrez Gene)
HCRTR1GeneProduct282248 (Entrez Gene)
HCRTR2GeneProduct529603 (Entrez Gene)
HRH1GeneProduct281231 (Entrez Gene)
HRH2GeneProduct521257 (Entrez Gene)
HRH3GeneProduct615267 (Entrez Gene)
HTR1AGeneProduct407137 (Entrez Gene)
HTR1BGeneProduct317707 (Entrez Gene)
HTR1DGeneProduct407136 (Entrez Gene)
HTR1EGeneProduct616356 (Entrez Gene)
HTR1FGeneProduct407196 (Entrez Gene)
HTR2AGeneProduct407230 (Entrez Gene)
HTR2BGeneProduct407135 (Entrez Gene)
HTR2CGeneProduct445435 (Entrez Gene)
HTR4GeneProduct317708 (Entrez Gene)
HTR5AGeneProduct541200 (Entrez Gene)
HTR6GeneProduct512167 (Entrez Gene)
HTR7GeneProduct538510 (Entrez Gene)
HistamineMetabolite
IL8RAGeneProduct
IL8RBGeneProduct782719 (Entrez Gene)
LHCGRGeneProduct281900 (Entrez Gene)
LOC504498GeneProduct504498 (Entrez Gene)
LOC505191GeneProduct505191 (Entrez Gene)
LOC507573GeneProduct507573 (Entrez Gene)
LOC509170GeneProduct509170 (Entrez Gene)
LOC509916GeneProduct509916 (Entrez Gene)
LOC513732GeneProduct513732 (Entrez Gene)
LOC514760GeneProduct514760 (Entrez Gene)
LOC521903GeneProduct521903 (Entrez Gene)
LOC524872GeneProduct524872 (Entrez Gene)
LOC528374GeneProduct528374 (Entrez Gene)
LOC528930GeneProduct528930 (Entrez Gene)
LOC532454GeneProduct532454 (Entrez Gene)
LOC532476GeneProduct532476 (Entrez Gene)
LOC538864GeneProduct538864 (Entrez Gene)
LOC538946GeneProduct538946 (Entrez Gene)
LOC539185GeneProduct539185 (Entrez Gene)
LOC539623GeneProduct539623 (Entrez Gene)
LOC540205GeneProduct540205 (Entrez Gene)
LOC540255GeneProduct540255 (Entrez Gene)
LOC616938GeneProduct616938 (Entrez Gene)
LOC617571GeneProduct617571 (Entrez Gene)
LOC618597GeneProduct618597 (Entrez Gene)
LOC782431GeneProduct782431 (Entrez Gene)
LOC784712GeneProduct784712 (Entrez Gene)
LOC785397GeneProduct785397 (Entrez Gene)
LOC788289GeneProduct788289 (Entrez Gene)
LPAR4GeneProduct539738 (Entrez Gene)
LTB4RGeneProduct613482 (Entrez Gene)
MAS1GeneProduct782151 (Entrez Gene)
MAS1LGeneProduct
MC1RGeneProduct281298 (Entrez Gene)
MC2RGeneProduct281299 (Entrez Gene)
MC3RGeneProduct
MC4RGeneProduct281300 (Entrez Gene)
MC5RGeneProduct507987 (Entrez Gene)
MCHR1GeneProduct540119 (Entrez Gene)
MLNRGeneProduct
MTNR1AGeneProduct539948 (Entrez Gene)
MTNR1BGeneProduct787599 (Entrez Gene)
NMBRGeneProduct539776 (Entrez Gene)
NMUR1GeneProduct539614 (Entrez Gene)
NMUR2GeneProduct507439 (Entrez Gene)
NPBWR1GeneProduct281207 (Entrez Gene)
NPFFR1GeneProduct540577 (Entrez Gene)
NPFFR2GeneProduct530560 (Entrez Gene)
NPY1RGeneProduct504813 (Entrez Gene)
NPY2RGeneProduct281943 (Entrez Gene)
NPY5RGeneProduct786150 (Entrez Gene)
NPY6RGeneProduct
NTSR1GeneProduct528416 (Entrez Gene)
NTSR2GeneProduct539336 (Entrez Gene)
OPN1LWGeneProduct282293 (Entrez Gene)
OPN1MWGeneProduct
OPN1SWGeneProduct282294 (Entrez Gene)
OPN3GeneProduct
OPN4GeneProduct515152 (Entrez Gene)
OPRD1GeneProduct781956 (Entrez Gene)
OPRK1GeneProduct540519 (Entrez Gene)
OPRL1GeneProduct
OPRM1GeneProduct281958 (Entrez Gene)
OR10A5GeneProduct
OR10H1GeneProduct508140 (Entrez Gene)
OR10H2GeneProduct
OR10H3GeneProduct
OR10J1GeneProduct
OR11A1GeneProduct
OR1A1GeneProduct
OR1A2GeneProduct
OR1C1GeneProduct
OR1D2GeneProduct
OR1D4GeneProduct
OR1E2GeneProduct
OR1F1GeneProduct
OR2A4GeneProduct
OR2AG1GeneProduct
OR2B2GeneProduct
OR2B3GeneProduct
OR2F1GeneProduct
OR2F2GeneProduct
OR2H1GeneProduct
OR2H2GeneProduct
OR2J1GeneProduct
OR2N1PGeneProduct
OR3A2GeneProduct
OR3A3GeneProduct
OR3A4GeneProduct
OR5F1GeneProduct
OR7A5GeneProduct
OR7C1GeneProduct
OXTRGeneProduct281371 (Entrez Gene)
P2RY10GeneProduct515172 (Entrez Gene)
P2RY11GeneProduct
P2RY12GeneProduct408007 (Entrez Gene)
P2RY1GeneProduct281963 (Entrez Gene)
P2RY13GeneProduct782774 (Entrez Gene)
P2RY14GeneProduct767936 (Entrez Gene)
P2RY2GeneProduct282638 (Entrez Gene)
P2RY4GeneProduct514653 (Entrez Gene)
P2RY5GeneProduct782518 (Entrez Gene)
P2RY6GeneProduct539703 (Entrez Gene)
PPYR1GeneProduct505889 (Entrez Gene)
PRLHRGeneProduct510397 (Entrez Gene)
PTAFRGeneProduct518283 (Entrez Gene)
PTGDRGeneProduct515331 (Entrez Gene)
PTGER1GeneProduct507437 (Entrez Gene)
PTGER2GeneProduct282329 (Entrez Gene)
PTGER3GeneProduct282330 (Entrez Gene)
PTGER4GeneProduct282331 (Entrez Gene)
PTGFRGeneProduct282020 (Entrez Gene)
PTGIRGeneProduct520278 (Entrez Gene)
ProstaglandinMetabolite
Q9UDD9GeneProduct
RHOGeneProduct509933 (Entrez Gene)
RRHGeneProduct539343 (Entrez Gene)
RgrGeneProduct280911 (Entrez Gene)
SSTR1GeneProduct540013 (Entrez Gene)
SSTR2GeneProduct282083 (Entrez Gene)
SSTR3GeneProduct518585 (Entrez Gene)
SSTR4GeneProduct
SSTR5GeneProduct510344 (Entrez Gene)
SUCNR1GeneProduct
SerotoninMetabolite
TBXA2RGeneProduct538783 (Entrez Gene)
TRHRGeneProduct281549 (Entrez Gene)
XCR1GeneProduct617880 (Entrez Gene)

Annotated Interactions

No annotated interactions
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