Actin cytoskeleton regulation (Bos taurus)

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Actin polymerizationstress fiberActin polymerization-pFocal adhesionassemblyGPCRFocal complexassembly?RTKPI3KGene ExpressionChemotatic factorActin polymerization+pstress fiberGrowth Factor (GF)GFStabilizationof actinRASRASPI3KActomyosinassembly contractionLamellipodiaGPCRRTKFilipodiaChemotactic factorFGF3APCPIP3MAPK4RASSF7SSH3FGFR4MAP2K1EGFRDOCK1FGF21PIP5K1BRAF1SOS2BradykininPAK4RAC2FGF17ACTG1FGF11KRASPDGFRAFGF6DIAP3GNA13CFL1ARHGEF6VIL1PIK3CDMAPK3RRAS2FGF7FGF9Focal AdhesionpathwayFGF23PIK3C3PAK7PIK3R3PIP2PIK3C2BFGF5CFL2FGF10BAIAP2PIK3R1PIK3C2GTMSB4XMRASFGF15PIP4K2AARHGEF6LOC100336547FGFR3FGF14ABI2CHRM5PIP2ACTG1RAC1P4PDGFRBFGF1GNA12EGFPIK3R2CHRM2PAK3F2RF2FGFR2MAP2K2PIP4K2CNRASFGF13PFN1PAK2ARPC5PIP5KL1ENAHVCLPIK3CGFGFR1PIP4K2BSLC9A1Focal AdhesionpathwayWASF2INS2FGF12CHRM1PDGFAFGF20MYH10DIAP1GSNCYFIP2PIK3R4BDKRB2RRASFGF2Adherens junctionpathwayITGA1FGF16FGF22PTK2LOC442775PPP1R12AARHGAP35VCLFGD1PAK1PXNPDGFBARHGEF7ARHGEF1MYLKMAPK1NCKAP1ACTBVAV1MYL1MOSCDC42CHRM4LIMK1CHRM3PIK3CBPIK3R5BRK1PIP5K1AAcetylcholineARHGEF4RDXPAK6RAC1ROCK1GNG12RHOAACTN1MSNFGF4BAIAP2WASF1RAC3MAPK SignalingpathwayPIK3C2AApc2SOS1ACTBGIT1BCAR1EZRCRKCD14ROCK2PIP4K2ABRAFACTBPFN1SSH1FGF8FN1INS1ARPC5PIP5K1CACTG1MYL3PIK3CAMAPK6FGF18SSH2CSKIQGAP1LPSBDKRB1


Description

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP51(r45278) with a 90% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
120933view09:05, 1 February 2022EgonwMade four pathways clickable
117595view11:36, 21 May 2021EweitzModified title
80894view15:30, 30 June 2015Mkutmonhomology conversion
72126view07:48, 25 October 2013Mkutmonadded datasource for pathway datanodes
71429view19:03, 17 October 2013MaintBotAutomated update of data sources
63458view17:18, 10 May 2013MaintBotUpdated to 2013 gpml schema
48126view05:45, 9 May 2012MaintBotUpdating from human to fix xref duplication
40593view19:33, 1 March 2011MaintBotRemoved redundant pathway information and comments
33830view00:28, 9 December 2009MaintBotAutomatic update of empty xrefs
32520view12:56, 17 August 2009MaintBotFixed text labels
32207view12:41, 15 August 2009MaintBotFixed text labels
31695view11:48, 14 August 2009MaintBotFixed group labels
31218view19:40, 13 August 2009MaintBotFixed text labels
30631view22:26, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ABI2GeneProduct537711 (Entrez Gene)
ACTBGeneProduct280979 (Entrez Gene)
ACTG1GeneProduct404122 (Entrez Gene)
ACTN1GeneProduct524770 (Entrez Gene)
APCGeneProduct533233 (Entrez Gene)
ARHGAP35GeneProduct540310 (Entrez Gene)
ARHGEF1GeneProduct513377 (Entrez Gene)
ARHGEF4GeneProduct505852 (Entrez Gene)
ARHGEF6GeneProduct533823 (Entrez Gene)
ARHGEF7GeneProduct524352 (Entrez Gene)
ARPC5GeneProduct614345 (Entrez Gene)
AcetylcholineMetabolite51-84-3 (CAS)
Adherens junction pathwayPathway
Apc2GeneProduct
BAIAP2GeneProduct507837 (Entrez Gene)
BCAR1GeneProduct527550 (Entrez Gene)
BDKRB1GeneProduct532119 (Entrez Gene)
BDKRB2GeneProduct538896 (Entrez Gene)
BRAFGeneProduct536051 (Entrez Gene)
BRK1GeneProduct540092 (Entrez Gene)
BradykininMetabolite58-82-2 (CAS)
CD14GeneProduct281048 (Entrez Gene)
CDC42GeneProduct532712 (Entrez Gene)
CFL1GeneProduct534553 (Entrez Gene)
CFL2GeneProduct539332 (Entrez Gene)
CHRM1GeneProduct281684 (Entrez Gene)
CHRM2GeneProduct522170 (Entrez Gene)
CHRM3GeneProduct281685 (Entrez Gene)
CHRM4GeneProduct512928 (Entrez Gene)
CHRM5GeneProduct281686 (Entrez Gene)
CRKGeneProduct512841 (Entrez Gene)
CSKGeneProduct509246 (Entrez Gene)
CYFIP2GeneProduct518833 (Entrez Gene)
DIAP1GeneProduct
DIAP3GeneProduct
DOCK1GeneProduct537203 (Entrez Gene)
EGFGeneProduct530315 (Entrez Gene)
EGFRGeneProduct407217 (Entrez Gene)
ENAHGeneProduct513095 (Entrez Gene)
EZRGeneProduct281574 (Entrez Gene)
F2GeneProduct280685 (Entrez Gene)
F2RGeneProduct526585 (Entrez Gene)
FGD1GeneProduct100124501 (Entrez Gene)
FGF10GeneProduct326285 (Entrez Gene)
FGF11GeneProduct613386 (Entrez Gene)
FGF12GeneProduct
FGF1GeneProduct281160 (Entrez Gene)
FGF13GeneProduct506924 (Entrez Gene)
FGF14GeneProduct
FGF15GeneProduct
FGF16GeneProduct540758 (Entrez Gene)
FGF17GeneProduct
FGF18GeneProduct533929 (Entrez Gene)
FGF20GeneProduct539083 (Entrez Gene)
FGF21GeneProduct785576 (Entrez Gene)
FGF22GeneProduct519657 (Entrez Gene)
FGF2GeneProduct281161 (Entrez Gene)
FGF23GeneProduct530239 (Entrez Gene)
FGF3GeneProduct618481 (Entrez Gene)
FGF4GeneProduct618474 (Entrez Gene)
FGF5GeneProduct536771 (Entrez Gene)
FGF6GeneProduct540317 (Entrez Gene)
FGF7GeneProduct616885 (Entrez Gene)
FGF8GeneProduct326284 (Entrez Gene)
FGF9GeneProduct613731 (Entrez Gene)
FGFR1GeneProduct281768 (Entrez Gene)
FGFR2GeneProduct404193 (Entrez Gene)
FGFR3GeneProduct281769 (Entrez Gene)
FGFR4GeneProduct317696 (Entrez Gene)
FN1GeneProduct
Focal Adhesion pathwayPathwayWP306
GIT1GeneProduct515088 (Entrez Gene)
GNA12GeneProduct515159 (Entrez Gene)
GNA13GeneProduct505611 (Entrez Gene)
GNG12GeneProduct286850 (Entrez Gene)
GSNGeneProduct535077 (Entrez Gene)
INS1GeneProduct
INS2GeneProduct
IQGAP1GeneProduct532715 (Entrez Gene)
ITGA1GeneProduct535951 (Entrez Gene)
KRASGeneProduct541140 (Entrez Gene)
LIMK1GeneProduct535225 (Entrez Gene)
LOC100336547GeneProduct100336547 (Entrez Gene)
LOC442775GeneProduct
LPSMetaboliteC00338 (Kegg Compound)
MAP2K1GeneProduct533199 (Entrez Gene)
MAP2K2GeneProduct510434 (Entrez Gene)
MAPK Signaling pathwayPathwayWP382
MAPK1GeneProduct327672 (Entrez Gene)
MAPK3GeneProduct531391 (Entrez Gene)
MAPK4GeneProduct
MAPK6GeneProduct538094 (Entrez Gene)
MOSGeneProduct444869 (Entrez Gene)
MRASGeneProduct540803 (Entrez Gene)
MSNGeneProduct540426 (Entrez Gene)
MYH10GeneProduct317655 (Entrez Gene)
MYL1GeneProduct317657 (Entrez Gene)
MYL3GeneProduct618352 (Entrez Gene)
MYLKGeneProduct
NCKAP1GeneProduct100300817 (Entrez Gene)
NRASGeneProduct506322 (Entrez Gene)
PAK1GeneProduct533729 (Entrez Gene)
PAK2GeneProduct513673 (Entrez Gene)
PAK3GeneProduct534526 (Entrez Gene)
PAK4GeneProduct539742 (Entrez Gene)
PAK6GeneProduct539224 (Entrez Gene)
PAK7GeneProduct513432 (Entrez Gene)
PDGFAGeneProduct505908 (Entrez Gene)
PDGFBGeneProduct540106 (Entrez Gene)
PDGFRAGeneProduct282301 (Entrez Gene)
PDGFRBGeneProduct527165 (Entrez Gene)
PFN1GeneProduct513895 (Entrez Gene)
PIK3C2AGeneProduct537790 (Entrez Gene)
PIK3C2BGeneProduct537396 (Entrez Gene)
PIK3C2GGeneProduct513301 (Entrez Gene)
PIK3C3GeneProduct534815 (Entrez Gene)
PIK3CAGeneProduct282306 (Entrez Gene)
PIK3CBGeneProduct517948 (Entrez Gene)
PIK3CDGeneProduct504531 (Entrez Gene)
PIK3CGGeneProduct530001 (Entrez Gene)
PIK3R1GeneProduct282307 (Entrez Gene)
PIK3R2GeneProduct282308 (Entrez Gene)
PIK3R3GeneProduct286865 (Entrez Gene)
PIK3R4GeneProduct507414 (Entrez Gene)
PIK3R5GeneProduct614838 (Entrez Gene)
PIP2MetaboliteC04637 (Kegg Compound)
PIP3MetaboliteC05981 (Kegg Compound)
PIP4K2AGeneProduct533289 (Entrez Gene)
PIP4K2BGeneProduct539211 (Entrez Gene)
PIP4K2CGeneProduct540005 (Entrez Gene)
PIP5K1AGeneProduct100125224 (Entrez Gene)
PIP5K1BGeneProduct537654 (Entrez Gene)
PIP5K1CGeneProduct508819 (Entrez Gene)
PIP5KL1GeneProduct523736 (Entrez Gene)
PPP1R12AGeneProduct
PTK2GeneProduct506270 (Entrez Gene)
PXNGeneProduct517456 (Entrez Gene)
RAC1GeneProduct281440 (Entrez Gene)
RAC1P4GeneProduct
RAC2GeneProduct327671 (Entrez Gene)
RAC3GeneProduct619066 (Entrez Gene)
RAF1GeneProduct521196 (Entrez Gene)
RASSF7GeneProduct538490 (Entrez Gene)
RDXGeneProduct517111 (Entrez Gene)
RHOAGeneProduct338049 (Entrez Gene)
ROCK1GeneProduct785911 (Entrez Gene)
ROCK2GeneProduct282041 (Entrez Gene)
RRAS2GeneProduct519269 (Entrez Gene)
RRASGeneProduct616503 (Entrez Gene)
SLC9A1GeneProduct317654 (Entrez Gene)
SOS1GeneProduct537682 (Entrez Gene)
SOS2GeneProduct100138040 (Entrez Gene)
SSH1GeneProduct538233 (Entrez Gene)
SSH2GeneProduct512652 (Entrez Gene)
SSH3GeneProduct514643 (Entrez Gene)
TMSB4XGeneProduct
VAV1GeneProduct617345 (Entrez Gene)
VCLGeneProduct783645 (Entrez Gene)
VIL1GeneProduct281573 (Entrez Gene)
WASF1GeneProduct531488 (Entrez Gene)
WASF2GeneProduct504482 (Entrez Gene)

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP1062"
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