G13 signaling pathway (Gallus gallus)

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1Activated Rho ADisassembly of ActinCytokinesis13Contraction & Actin-MyosinInteraction, Focal AdhesionStress Fiber ContractionStressFiber DisappearanceMembrane RufflingAnti-ApoptoticActin ReorganizationCell-Cell AdhesionGActin PolymerizationFilopodia FormationActin PolymerizationPIP4K2ASH3RF1TNK2CFL1PFN1PIK3CAMAP3K4PKN1RHOACDC42p140 Sra-1IQGAP2MYL1IQGAP1RAC1MAPK10PIK3CDRHPN2PIK3R2ROCK2RCJMB04_4j14ROCK1CITRTKNCFL2DIAPH1ARHGDIGARHGEF1WASMYBPHPPP1CBCALM1PIK3CBARHGDIBLIMK1GNA13WASLPAK3


Description

The G13 subunit is an alpha unit of heterotrimeric G proteins that regulates cell processes through the use of guanine nucleotide exchange factors. G13 regulates actin cytoskeletal remodeling in cells and is essential for receptor tyrosine kinase-induced migration of fibroblast and endothelial cells. Source: Wikipedia

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP524(r21780) with a 73% conversion rate.

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Ontology Terms

 

Bibliography

  1. Neves SR, Ram PT, Iyengar R; ''G protein pathways.''; Science, 2002 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
117199view10:33, 18 May 2021EweitzModified title
95755view14:07, 19 January 2018MkutmonHomology conversion update
72065view17:31, 24 October 2013MaintBotremoved data source from nodes without identifier
72013view12:24, 24 October 2013Mkutmonfixed connected lines
68853view17:20, 8 July 2013MaintBotUpdated to 2013 gpml schema
67278view10:30, 26 June 2013Christine ChichesterOntology Term : 'G protein mediated signaling pathway via Galpha12/Galpha13 family' added !
62675view18:31, 1 May 2013MaintBotUpdated Ensembl and UniProt data source
40991view22:55, 1 March 2011MaintBotRemoved redundant pathway information and comments
35417view10:36, 12 February 2010ThomasModified description
35416view10:35, 12 February 2010Thomasremoved braces, fixed labels, added literature
33913view18:04, 9 December 2009MaintBotAutomatic update of empty xrefs
33497view15:12, 30 November 2009MaintBotRemoved group label
32476view17:36, 15 August 2009MaintBotFixed text labels
31543view21:49, 13 August 2009MaintBotFixed text labels
30395view21:07, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ARHGDIBGeneProduct417941 (Entrez Gene)
ARHGDIGGeneProduct
ARHGEF1GeneProduct
CALM1GeneProduct396523 (Entrez Gene)
CDC42GeneProduct395917 (Entrez Gene)
CFL1GeneProduct100309654 (Entrez Gene)
CFL2GeneProduct423320 (Entrez Gene)
CITGeneProduct416984 (Entrez Gene)
DIAPH1GeneProduct374040 (Entrez Gene)
GNA13GeneProduct417434 (Entrez Gene)
IQGAP1GeneProduct415591 (Entrez Gene)
IQGAP2GeneProduct427211 (Entrez Gene)
LIMK1GeneProduct373922 (Entrez Gene)
MAP3K4GeneProduct421579 (Entrez Gene)
MAPK10GeneProduct422592 (Entrez Gene)
MYBPHGeneProduct421154 (Entrez Gene)
MYL1GeneProduct396470 (Entrez Gene)
PAK3GeneProduct422342 (Entrez Gene)
PFN1GeneProduct
PIK3CAGeneProduct424971 (Entrez Gene)
PIK3CBGeneProduct424826 (Entrez Gene)
PIK3CDGeneProduct419444 (Entrez Gene) P42338
PIK3R2GeneProduct771142 (Entrez Gene)
PIP4K2AGeneProduct420504 (Entrez Gene)
PKN1GeneProduct
PPP1CBGeneProduct396019 (Entrez Gene)
RAC1GeneProduct395871 (Entrez Gene)
RCJMB04_4j14GeneProduct417637 (Entrez Gene) A41687
RHOAGeneProduct395442 (Entrez Gene)
RHPN2GeneProduct415771 (Entrez Gene)
ROCK1GeneProduct373970 (Entrez Gene) S69211
ROCK2GeneProduct374182 (Entrez Gene) BAA31594
RTKNGeneProduct
SH3RF1GeneProduct422434 (Entrez Gene) Posh
TNK2GeneProduct431014 (Entrez Gene) S33596
WASGeneProduct
WASLGeneProduct417750 (Entrez Gene)
p140 Sra-1GeneProduct

Annotated Interactions

No annotated interactions
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