Insulin signaling (Gallus gallus)
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1
Glucose Transport
Translation Regulation
Ras-MAPK Signaling
PI 3-Kinase
Insulin Receptor Substrates
p90 Rsk Kinases
Modulators of Insulin Action
p70 S6 Kinases
Transcriptional Regulators & Immediate Early Genes
Metabolic Regulation
Tor Signaling
PDK/Akt Signaling
Vesicular Trafficking
MEK/MAP Kinases
PIK3R2
SOS1
PRKCB
MAP2K7
SGK2
SORBS1
RCJMB04_5i17
PIK3CD
MAP3K12
MYO1C
RCJMB04_16p24
RAC2
MAP3K14
TBC1D4
MAP3K5
PTPN11
SHC3
PSCD3
STXBP4
MAPK13
TSC1
GRB14
SGK3
MINK1
RCJMB04_36h7
PFKL
RPS6KA4
PPP1R3A
PRKAA1
SHC2
SRF
TSC2
PRKCD
MAPK12
MAP3K6
VAMP2
RAF1
MAPK8
RAC1
PTEN
MAP3K13
STXBP3
PRKCH
MAP4K4
EHD2
FRAP1
XBP1
GAB1
STX4A
MAP4K2
MAPK11
PRKCZ
EIF4EBP1
MAP3K4
KIF3A
MAP3K1
TRIB3
IRS1
MAP3K3
FOXO3
INPPL1
RPS6KA5
MAP2K4
SOS2
RRAD
IKBKB
MAP4K5
INSR
PIK3R3
RPS6KA3
RPS6KB2
MAPK10
SGK1
PIK3R4
IGF1R
IRS2
SNAP23
GSK3B
MAPK8
LIPE
AKT2
EIF4E
PRKAA2
SLC2A4
SHC1
PDPK1
KIF5B
PIK3CG
MAP4K3
RAB4A
ARF1
SNX26
MAPK1
PIK3CA
ENPP1
PIK3C2A
MAP3K9
STXBP1
RCJMB04_4j14
ELK1
MAPK3
RCJMB04_5a10
RPS6KA2
RHEB
RAPGEF1
MAPK4
MAP3K2
JUN
FOXO1A
MAP3K10
CRK
GYG1
PTPN1
RHOJ
MAP4K1
GRB2
CBL
MAPK14
GYS1
MAP3K11
CAP1
FLOT1
SOCS3
PIK3CB
SLC2A1
FOS
RHOQ
MAPK7
MAP2K1
EGR1
MAP2K2
PRKCQ
AKT1
MAP3K8
GRB10
STXBP2
MAPK9
RPS6KA6
GYS2
RCJMB04_8f10
CBLB
CBLC
IRS4
HRAS
ARF6
IRS3
INPP4A
PIK3C2G
PIK3C3
SNAP25
PIK3R1
RPS6KA1
PFKM
MAP3K7
SOCS1
SH2B2
MAP2K6
EHD1
GSK3A
PTPRF
RCJMB04_34i9
Description
No description
Comments
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP481(r28132)
with a 72% conversion rate.
Try the New WikiPathways
View approved pathways at
the new wikipathways.org
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Quality Tags
Ontology Terms
Saving...
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Bibliography
Quon MJ, Campfield LA; ''A mathematical model and computer simulation study of insulin sensitive glucose transporter regulation.''; J Theor Biol, 1991
PubMed
Europe PMC
Scholia
Bevan P; ''Insulin signalling.''; J Cell Sci, 2001
PubMed
Europe PMC
Scholia
Saltiel AR, Kahn CR; ''Insulin signalling and the regulation of glucose and lipid metabolism.''; Nature, 2001
PubMed
Europe PMC
Scholia
History
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Compare
Revision
Action
Time
User
Comment
116788
view
09:57, 14 May 2021
Eweitz
Modified title
95775
view
14:28, 19 January 2018
Mkutmon
Homology conversion update
74226
view
15:18, 8 April 2014
Egonw
Removed a data source where no ID was given.
68843
view
17:19, 8 July 2013
MaintBot
Updated to 2013 gpml schema
67396
view
10:55, 26 June 2013
Ddigles
Ontology Term : 'insulin signaling pathway' added !
47787
view
16:22, 6 April 2012
Khanspers
updated xref
40981
view
22:55, 1 March 2011
MaintBot
Removed redundant pathway information and comments
33905
view
18:01, 9 December 2009
MaintBot
Automatic update of empty xrefs
33433
view
14:55, 30 November 2009
MaintBot
Removed group label
31487
view
21:28, 13 August 2009
MaintBot
Fixed text labels
30312
view
20:40, 29 July 2009
MaintBot
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
AKT1
GeneProduct
395928 (Entrez Gene)
AKT2
GeneProduct
373973 (Entrez Gene)
ARF1
GeneProduct
420398 (Entrez Gene)
ARF6
GeneProduct
428927 (Entrez Gene)
CAP1
GeneProduct
419680 (Entrez Gene)
CBL
GeneProduct
374038 (Entrez Gene)
CBLB
GeneProduct
418406 (Entrez Gene)
CBLC
GeneProduct
CRK
GeneProduct
417553 (Entrez Gene)
EGR1
GeneProduct
373931 (Entrez Gene)
EHD1
GeneProduct
EHD2
GeneProduct
EIF4E
GeneProduct
422703 (Entrez Gene)
EIF4EBP1
GeneProduct
426773 (Entrez Gene)
ELK1
GeneProduct
ENPP1
GeneProduct
426929 (Entrez Gene)
FLOT1
GeneProduct
FOS
GeneProduct
396512 (Entrez Gene)
FOXO1A
GeneProduct
374231 (Entrez Gene)
FOXO3
GeneProduct
421769 (Entrez Gene)
FRAP1
GeneProduct
419455 (Entrez Gene)
GAB1
GeneProduct
422456 (Entrez Gene)
GRB10
GeneProduct
420948 (Entrez Gene)
GRB14
GeneProduct
424183 (Entrez Gene)
GRB2
GeneProduct
386572 (Entrez Gene)
GSK3A
GeneProduct
GSK3B
GeneProduct
418335 (Entrez Gene)
GYG1
GeneProduct
425050 (Entrez Gene)
GYS1
GeneProduct
378934 (Entrez Gene)
GYS2
GeneProduct
418201 (Entrez Gene)
HRAS
GeneProduct
396229 (Entrez Gene)
IGF1R
GeneProduct
395889 (Entrez Gene)
IKBKB
GeneProduct
426792 (Entrez Gene)
INPP4A
GeneProduct
418690 (Entrez Gene)
INPPL1
GeneProduct
428692 (Entrez Gene)
INSR
GeneProduct
420133 (Entrez Gene)
IRS1
GeneProduct
429126 (Entrez Gene)
IRS2
GeneProduct
428017 (Entrez Gene)
IRS3
GeneProduct
IRS4
GeneProduct
JUN
GeneProduct
424673 (Entrez Gene)
KIF3A
GeneProduct
416332 (Entrez Gene)
KIF5B
GeneProduct
420472 (Entrez Gene)
LIPE
GeneProduct
MAP2K1
GeneProduct
415549 (Entrez Gene)
MAP2K2
GeneProduct
396349 (Entrez Gene)
MAP2K4
GeneProduct
417312 (Entrez Gene)
MAP2K6
GeneProduct
MAP2K7
GeneProduct
MAP3K10
GeneProduct
MAP3K11
GeneProduct
MAP3K12
GeneProduct
MAP3K13
GeneProduct
424876 (Entrez Gene)
MAP3K1
GeneProduct
427144 (Entrez Gene)
MAP3K14
GeneProduct
419964 (Entrez Gene)
MAP3K2
GeneProduct
424225 (Entrez Gene)
MAP3K3
GeneProduct
419954 (Entrez Gene)
MAP3K4
GeneProduct
421579 (Entrez Gene)
MAP3K5
GeneProduct
421688 (Entrez Gene)
MAP3K6
GeneProduct
MAP3K7
GeneProduct
421808 (Entrez Gene)
MAP3K8
GeneProduct
420479 (Entrez Gene)
MAP3K9
GeneProduct
776822 (Entrez Gene)
MAP4K1
GeneProduct
MAP4K2
GeneProduct
MAP4K3
GeneProduct
425965 (Entrez Gene)
MAP4K4
GeneProduct
418714 (Entrez Gene)
MAP4K5
GeneProduct
423576 (Entrez Gene)
MAPK10
GeneProduct
422592 (Entrez Gene)
MAPK11
GeneProduct
417739 (Entrez Gene)
MAPK12
GeneProduct
769763 (Entrez Gene)
MAPK1
GeneProduct
373953 (Entrez Gene)
MAPK13
GeneProduct
771145 (Entrez Gene)
MAPK14
GeneProduct
421183 (Entrez Gene)
MAPK3
GeneProduct
MAPK4
GeneProduct
MAPK7
GeneProduct
MAPK8
GeneProduct
423778 (Entrez Gene)
MAPK9
GeneProduct
395983 (Entrez Gene)
MINK1
GeneProduct
MYO1C
GeneProduct
417555 (Entrez Gene)
PDPK1
GeneProduct
416588 (Entrez Gene)
PFKL
GeneProduct
769850 (Entrez Gene)
PFKM
GeneProduct
374064 (Entrez Gene)
PIK3C2A
GeneProduct
423070 (Entrez Gene)
PIK3C2G
GeneProduct
418181 (Entrez Gene)
PIK3C3
GeneProduct
PIK3CA
GeneProduct
424971 (Entrez Gene)
PIK3CB
GeneProduct
424826 (Entrez Gene)
PIK3CD
GeneProduct
419444 (Entrez Gene)
PIK3CG
GeneProduct
417706 (Entrez Gene)
PIK3R1
GeneProduct
427171 (Entrez Gene)
PIK3R2
GeneProduct
771142 (Entrez Gene)
PIK3R3
GeneProduct
429096 (Entrez Gene)
PIK3R4
GeneProduct
428449 (Entrez Gene)
PPP1R3A
GeneProduct
427858 (Entrez Gene)
PRKAA1
GeneProduct
427185 (Entrez Gene)
PRKAA2
GeneProduct
429110 (Entrez Gene)
PRKCB
GeneProduct
416567 (Entrez Gene)
PRKCD
GeneProduct
415905 (Entrez Gene)
PRKCH
GeneProduct
423518 (Entrez Gene)
PRKCQ
GeneProduct
PRKCZ
GeneProduct
419399 (Entrez Gene)
PSCD3
GeneProduct
416626 (Entrez Gene)
PTEN
GeneProduct
423675 (Entrez Gene)
PTPN11
GeneProduct
395815 (Entrez Gene)
PTPN1
GeneProduct
395688 (Entrez Gene)
PTPRF
GeneProduct
424568 (Entrez Gene)
RAB4A
GeneProduct
421532 (Entrez Gene)
RAC1
GeneProduct
395871 (Entrez Gene)
RAC2
GeneProduct
418044 (Entrez Gene)
RAF1
GeneProduct
396245 (Entrez Gene)
RAPGEF1
GeneProduct
417173 (Entrez Gene)
RCJMB04_16p24
GeneProduct
424991 (Entrez Gene)
RCJMB04_34i9
GeneProduct
417579 (Entrez Gene)
RCJMB04_36h7
GeneProduct
415557 (Entrez Gene)
RCJMB04_4j14
GeneProduct
417637 (Entrez Gene)
RCJMB04_5a10
GeneProduct
417430 (Entrez Gene)
RCJMB04_5i17
GeneProduct
415419 (Entrez Gene)
RCJMB04_8f10
GeneProduct
416496 (Entrez Gene)
RHEB
GeneProduct
420434 (Entrez Gene)
RHOJ
GeneProduct
423513 (Entrez Gene)
RHOQ
GeneProduct
395114 (Entrez Gene)
RPS6KA1
GeneProduct
386579 (Entrez Gene)
RPS6KA2
GeneProduct
421570 (Entrez Gene)
RPS6KA3
GeneProduct
418605 (Entrez Gene)
RPS6KA4
GeneProduct
RPS6KA5
GeneProduct
423408 (Entrez Gene)
RPS6KA6
GeneProduct
422273 (Entrez Gene)
RPS6KB2
GeneProduct
RRAD
GeneProduct
415790 (Entrez Gene)
SGK1
GeneProduct
395133 (Entrez Gene)
SGK2
GeneProduct
419166 (Entrez Gene)
SGK3
GeneProduct
420167 (Entrez Gene)
SH2B2
GeneProduct
771172 (Entrez Gene)
SHC1
GeneProduct
395934 (Entrez Gene)
SHC2
GeneProduct
770341 (Entrez Gene)
SHC3
GeneProduct
431265 (Entrez Gene)
SLC2A1
GeneProduct
396130 (Entrez Gene)
SLC2A4
GeneProduct
SNAP23
GeneProduct
423235 (Entrez Gene)
SNAP25
GeneProduct
396444 (Entrez Gene)
SNX26
GeneProduct
SOCS1
GeneProduct
416630 (Entrez Gene)
SOCS3
GeneProduct
395299 (Entrez Gene)
SORBS1
GeneProduct
423749 (Entrez Gene)
SOS1
GeneProduct
425964 (Entrez Gene)
SOS2
GeneProduct
423572 (Entrez Gene)
SRF
GeneProduct
396103 (Entrez Gene)
STX4A
GeneProduct
STXBP1
GeneProduct
404293 (Entrez Gene)
STXBP2
GeneProduct
STXBP3
GeneProduct
424341 (Entrez Gene)
STXBP4
GeneProduct
417393 (Entrez Gene)
TBC1D4
GeneProduct
428062 (Entrez Gene)
TRIB3
GeneProduct
TSC1
GeneProduct
417166 (Entrez Gene)
TSC2
GeneProduct
416552 (Entrez Gene)
VAMP2
GeneProduct
424827 (Entrez Gene)
XBP1
GeneProduct
416918 (Entrez Gene)
Annotated Interactions
No annotated interactions
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Try the New WikiPathways
View approved pathways at the new wikipathways.org.Quality Tags
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Bibliography
History
External references
DataNodes
Annotated Interactions
No annotated interactions