Prostaglandin synthesis and regulation (Rattus norvegicus)

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CytoplasmCell MembranePhospholipidsGq signalingpathwayCortisonePG SynthasesprolactinreleaseInactive MetabolitesArachidonic AcidAnxa1Cyp11a1PrlPtgs1Ptger2Ptger3EdnraHpgdEdnrbS100a6PGF2aAnxa6Anxa5PTGDRHsd11b2PtgisPtgdsPtgs2Edn1CalciumANXA8Pla2g4aS100a10CortisolPGF2aTXA2ProgesteronePtgfrAnxa3Scgb1a1CortisolPGE2CalciumHsd11b1Anxa2Ptger1PtgirProstaglandin H2Tbxas1Anxa4Ptger4PGI2


Description

No description

Comments

GenMAPP notes 
Adapted from Gross, G et al. 2000, Society for Gynecologic Investigation; 7:88-95
GenMAPP remarks 
See note for more details
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP98(r20887) with a 80% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
117006view11:20, 16 May 2021EweitzModified title
109407view18:00, 16 March 2020L DupuisConverted interactions to graphical lines
106976view13:43, 17 September 2019MaintBotHMDB identifier normalization
71789view20:33, 17 October 2013MaintBotAutomated update of data sources
69399view18:59, 8 July 2013MaintBotUpdated to 2013 gpml schema
67607view11:32, 26 June 2013DdiglesOntology Term : 'prostaglandin metabolic pathway' added !
41716view02:38, 2 March 2011MaintBotRemoved redundant pathway information and comments
34095view19:17, 9 December 2009MaintBotAutomatic update of empty xrefs
32392view16:59, 15 August 2009MaintBotFixed text labels
32040view13:28, 14 August 2009MaintBotFixed group labels
31427view21:00, 13 August 2009MaintBotFixed text labels
30941view00:40, 30 July 2009MaintBotConverted from Homo sapiens
21317view11:31, 14 November 2008MaintBot[[Pathway:Rattus norvegicus:Prostaglandin synthesis regulation]] moved to [[Pathway:WP303]]: Moved to stable identifier
8346view13:46, 7 January 2008MaintBot[[Pathway:Rat:Prostaglandin synthesis regulation]] moved to [[Pathway:Rattus norvegicus:Prostaglandin synthesis regulation]]: Renaming species
7791view16:17, 18 December 2007MaintBotfixed category names
7394view12:42, 4 November 2007MaintBotAdded categories to GPML
6587view22:20, 22 May 2007Nsalomonisgpml file for [[Rat:Prostaglandin_synthesis_regulation]]

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ANXA8GeneProduct306283 (Entrez Gene)
Anxa1GeneProduct25380 (Entrez Gene)
Anxa2GeneProduct56611 (Entrez Gene)
Anxa3GeneProduct25291 (Entrez Gene)
Anxa4GeneProduct79124 (Entrez Gene)
Anxa5GeneProduct25673 (Entrez Gene)
Anxa6GeneProduct79125 (Entrez Gene)
Arachidonic AcidMetabolite
CalciumMetaboliteHMDB00464 (HMDB)
CortisolMetabolite
Cyp11a1GeneProduct29680 (Entrez Gene)
Edn1GeneProduct24323 (Entrez Gene) PMID: 1474344
EdnraGeneProduct24326 (Entrez Gene)
EdnrbGeneProduct50672 (Entrez Gene)
HpgdGeneProduct79242 (Entrez Gene)
Hsd11b1GeneProduct25116 (Entrez Gene)
Hsd11b2GeneProduct25117 (Entrez Gene)
PGE2MetaboliteHMDB03175 (HMDB)
PGF2aMetaboliteHMDB01139 (HMDB)
PGI2MetaboliteHMDB01335 (HMDB)
PTGDRGeneProduct498475 (Entrez Gene)
Pla2g4aGeneProduct24653 (Entrez Gene)
PrlGeneProduct24683 (Entrez Gene)
ProgesteroneMetabolite
Prostaglandin H2Metabolite
PtgdsGeneProduct25526 (Entrez Gene)
Ptger1GeneProduct25637 (Entrez Gene)
Ptger2GeneProduct81752 (Entrez Gene)
Ptger3GeneProduct24929 (Entrez Gene)
Ptger4GeneProduct84023 (Entrez Gene)
PtgfrGeneProduct25652 (Entrez Gene)
PtgirGeneProduct292661 (Entrez Gene)
PtgisGeneProduct25527 (Entrez Gene)
Ptgs1GeneProduct24693 (Entrez Gene)
Ptgs2GeneProduct29527 (Entrez Gene)
S100a10GeneProduct81778 (Entrez Gene) PMID: 12962548 relationship with Annexin 2
S100a6GeneProduct85247 (Entrez Gene)
Scgb1a1GeneProduct25575 (Entrez Gene) PMID: 7615804, PMID: 3292559
TXA2MetaboliteHMDB01452 (HMDB)
Tbxas1GeneProduct24886 (Entrez Gene)

Annotated Interactions

No annotated interactions
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