IL-4 signaling pathway (Danio rerio)

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RecruitmentAcetylationNUERCY -> PMGolgi apparatusMolecular associationLigandDNucleusGOPalmitoylationInhibitionGlycosylationProteolytic cleavageCY -> PMCY -> NUReceptorTranslocationDAccession Number: NetPath 16Endoplasmic reticulumPlasma membraneProteins in a complex interactionDENECDemethylationActivationCY -> PMControlEndosomeCY -> NUMolecule in the pathwaySumoylationMTPMReaction through unknown mechanisms/moleculesUbiquitinationDMitochondrionDephosphorylationMethylationDeubiquitinationAutophosphorylationDeacetylationPhosphorylationDCytoplasmExtracellularCYCY -> PMEnzyme complexD(Protein-protein interaction)DDesumoylationDDLOC566983LOC792354TYK2Gene Symbolmapk1HMGA1IRS2LOC561737CXCR4grb2IL4FESmapk14aLCKLOC559103ptpn6NFKB1spi1atf2lPRKCDadrbk2mapk3BADrps6kb1LOC566983pik3r2relaprkciprkczprkczHIST2H3Cptk2.1jak2bjak2bpik3cdfynbcblSOS1srcjak1LOC563639IL2RGstat1aprkciIL4LOC566983IL4Rptpn11LOC557337JAK3ets1asocs1LOC567895LOC557337plcg1SOCS3IL4Rcrebbpbmapk14aSTAT5ALOC559281SOCS5IL13RA1ep300arasa1LOC566983NCF1NFKB1DOK2LOC557176pawrljak1zgc:86905bcl2lPRKCDstamLOC566983


Description

No description

Comments

GenMAPP notes 
NetPath 16 - IL-4 Signaling Pathway

NetPath (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the NetPath website until the pathway is published.

GenMAPP remarks 
http://www.netpath.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP395(r28126) with a 66% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
117985view11:23, 23 May 2021EweitzModified title
86930view13:05, 15 July 2016MkutmonOntology Term : 'interleukin-4 signaling pathway' added !
68697view05:59, 6 July 2013MaintBotUpdated to 2013 gpml schema
40873view22:21, 1 March 2011MaintBotRemoved redundant pathway information and comments
34253view21:45, 9 December 2009MaintBotAutomatic update of empty xrefs
31384view20:42, 13 August 2009MaintBotFixed text labels
31088view01:35, 30 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
BADGeneProduct58100 (Entrez Gene)
CXCR4GeneProduct
DOK2GeneProduct
FESGeneProduct
Gene SymbolGeneProduct
HIST2H3CGeneProduct
HMGA1GeneProduct
IL13RA1GeneProduct799475 (Entrez Gene)
IL2RGGeneProduct
IL4GeneProduct
IL4RGeneProduct503594 (Entrez Gene)
IRS2GeneProduct
JAK3GeneProduct561370 (Entrez Gene)
LCKGeneProduct414333 (Entrez Gene)
LOC557176GeneProduct557176 (Entrez Gene)
LOC557337GeneProduct557337 (Entrez Gene)
LOC559103GeneProduct559103 (Entrez Gene)
LOC559281GeneProduct559281 (Entrez Gene)
LOC561737GeneProduct561737 (Entrez Gene)
LOC563639GeneProduct563639 (Entrez Gene)
LOC566983GeneProduct566983 (Entrez Gene)
LOC567895GeneProduct567895 (Entrez Gene)
LOC792354GeneProduct792354 (Entrez Gene)
NCF1GeneProduct378966 (Entrez Gene)
NFKB1GeneProduct565756 (Entrez Gene)
PRKCDGeneProduct334571 (Entrez Gene)
SOCS3GeneProduct
SOCS5GeneProduct
SOS1GeneProduct
STAT5AGeneProduct
TYK2GeneProduct
adrbk2GeneProduct569403 (Entrez Gene)
atf2lGeneProduct100006516 (Entrez Gene)
bcl2lGeneProduct114401 (Entrez Gene)
cblGeneProduct492364 (Entrez Gene)
crebbpbGeneProduct503776 (Entrez Gene)
ep300aGeneProduct559273 (Entrez Gene)
ets1aGeneProduct280651 (Entrez Gene)
fynbGeneProduct574422 (Entrez Gene)
grb2GeneProduct406308 (Entrez Gene)
jak1GeneProduct30280 (Entrez Gene)
jak2bGeneProduct30298 (Entrez Gene)
mapk1GeneProduct360144 (Entrez Gene)
mapk14aGeneProduct65237 (Entrez Gene)
mapk3GeneProduct399480 (Entrez Gene)
pawrlGeneProduct449994 (Entrez Gene)
pik3cdGeneProduct394174 (Entrez Gene)
pik3r2GeneProduct404211 (Entrez Gene)
plcg1GeneProduct373867 (Entrez Gene)
prkciGeneProduct117507 (Entrez Gene)
prkczGeneProduct555737 (Entrez Gene)
ptk2.1GeneProduct142986 (Entrez Gene)
ptpn11GeneProduct333979 (Entrez Gene)
ptpn6GeneProduct335573 (Entrez Gene)
rasa1GeneProduct100002155 (Entrez Gene)
relaGeneProduct415099 (Entrez Gene)
rps6kb1GeneProduct406349 (Entrez Gene)
socs1GeneProduct445073 (Entrez Gene)
spi1GeneProduct30117 (Entrez Gene)
srcGeneProduct325084 (Entrez Gene)
stamGeneProduct386967 (Entrez Gene)
stat1aGeneProduct30768 (Entrez Gene)
zgc:86905GeneProduct415185 (Entrez Gene)

Annotated Interactions

No annotated interactions
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