Metapathway biotransformation (Bos taurus)
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N-acetyltransferases
Glutathione synthetase
Nucleophiles
Glucuronidation
Cytochrome P450
Acetylation
Epoxide hydrolases
Glutathione peroxidases
Glutathione transferases
Reduction
Hydrolysis
Sulfotransferases
Electrophiles
Aldo-keto reductases
Flavin monooxygenases
Methyltransferases
Sulfation
Amino acid acyl transferases
Glutathione conjugation
Oxidation
Glucuronosyltransferases
Glutathione reductase
Amino acid conjugation
Methylation
CYP4F12
IPI00708458.2
IPI00693008.2
CHST9
NP_001071381.1
IPI00686912.3
Glucuronosyltransferase
NP_001068630.1
N-acetyltransferase
NP_001071429.1
UGT2B7
LOC614317
GSTA3
NP_001073084.1
NP_001092474.1
G3ST3_BOVIN
Sulfotransferase
IPI00713683.4
LOC515352
CYP3A5
NP_001093836.1
GPX4_BOVIN
HS3ST3A1
ST1A1_BOVIN
CYP2C8
UGT1A5
CYP27B1
UGT1A7
IPI00700522.1
UGT1A10
ST1A1_BOVIN
CYP2J2
IPI00702562.3
NP_001077117.1
UGT2B15
IPI00705496.1
G3ST1_BOVIN
UGT1A9
CYP2C18
NP_001092414.1
IPI00693768.3
IPI00695153.3
MGST3_BOVIN
NP_001076882.1
CHST14
NP_001091500.1
UGT2A1
Substrate-Ac
CYP4F8
AKR7A3
IPI00906116.1
NP_001069002.1
GSTO1
Xenobiotic substrate
NAT13_BOVIN
AKR1C1
NP_001075096.1
UGT2B4
GSTT2
Substrate-Aa
AK1A1_BOVIN
HS3ST3B1
CP51A_BOVIN
IPI00689284.1
IPI00903985.1
IPI00704129.5
UGT2A2
CYP4F11
IPI00709378.3
IPI00697335.1
GSTCD_BOVIN
Flavin monooxygenase
CYP2A13
CHST8
CYP19A1
ST1A1_BOVIN
GSTA4_BOVIN
NM_001075173.1
GSTA2
Substrate-SO3H
NAT14_BOVIN
NP_001029801.1
CYP21A2
Substrate=O
UGT1A3
A6H748_BOVIN
MGST2_BOVIN
GSTA5
IPI00687876.3
ARY1_BOVIN
UGT1A6
IPI00726067.3
Amino acid acyltransferase
NP_001095549.1
NP_777187.1
IPI00904186.1
SULT2B1
IPI00688142.3
NDST2_BOVIN
IPI00698655.1
CP2U1_BOVIN
NNMT
CYP450
NP_001069683.1
G3ST4_BOVIN
IPI00693008.2
AKR1C3
CYP2A7
Substrate-SG
UGT1A1
COMT_BOVIN
NP_001092408.1
ST1B1_BOVIN
NP_001069613.1
NP_001029545.1
NP_001069986.1
IPI00906608.1
KCAB2_BOVIN
KCAB1_BOVIN
CYP2A6
IPI00688083.3
IPI00716958.3
CYP17A1
ARY1_BOVIN
GPX1_BOVIN
GSTT1
AKR7A2
CYP4Z1
Substrate-SH
GSTP1_BOVIN
CYP2C19
NP_001069670.1
Glutathione transferase
AKR1C4
Substrate-NH2
UGT1A4
NAT8
ST1A1_BOVIN
Substrate-Gl
SULT1C2
CYP4F2
Substrate-CH3
HS6ST2
GSTM1
IPI00710606.2
ST1E1_BOVIN
GLYATL1
CYP3A43
HNMT_BOVIN
GSTM4
NP_001091480.1
CYP3A4
CYP11B1
Methyltransferase
IPI00701497.5
CYP2F1
GSTT2B
Substrate-OH
XR_027890.2
IPI00716297.1
UGT2B28
AKR1C2
IPI00695412.4
GSTM2
NP_001094774.1
FMO3
UGT2B17
Q95KN3_BOVIN
CP2E1_BOVIN
AKR1B1
IPI00694081.4
Substrate-O-R
NP_001020506.1
CYP2C9
CP20A_BOVIN
IPI00698855.3
IPI00705153.2
NP_001040025.1
IPI00699039.4
Aldo-keto reductase
CYP46A1
NP_001095558.1
NP_001069154.1
NP_001069590.1
CYP3A7
CYP2D6
NP_001069735.1
NP_001096716.1
A9CSS1_BOVIN
SULT1C4
A6QPJ8_BOVIN
GPX2
GSHB_BOVIN
GSTA1
TPMT_BOVIN
UGT2B11
CP11A_BOVIN
HS3ST4
GLYAT
NP_001069607.1
IPI00709424.4
IPI00692810.3
GSTM5
MGST1_BOVIN
CYP4F22
CYP11B2
SULT2A1
IPI00905203.2
GPX3_BOVIN
Description
No description
Comments
HomologyConvert
This pathway was inferred from Homo sapiens pathway
WP702(r29945)
with a 58% conversion rate.
Try the New WikiPathways
View approved pathways at
the new wikipathways.org
.
Quality Tags
Ontology Terms
Saving...
No Tags!
Bibliography
No bibliography
History
View all...
Compare
Revision
Action
Time
User
Comment
80841
view
15:28, 30 June 2015
Mkutmon
homology conversion
70171
view
00:39, 13 July 2013
AlexanderPico
Modified title
63459
view
17:18, 10 May 2013
MaintBot
Updated to 2013 gpml schema
58827
view
23:19, 20 February 2013
MaintBot
Updated Ensembl and UniProt data source
53460
view
18:40, 7 November 2012
Andra
Added missing Entrez Gene Id's after RDF Tidy
40594
view
19:33, 1 March 2011
MaintBot
Removed redundant pathway information and comments
33831
view
00:29, 9 December 2009
MaintBot
Automatic update of empty xrefs
33196
view
18:19, 5 November 2009
Khanspers
Modified categories
32487
view
12:45, 17 August 2009
MaintBot
Fixed text labels
32182
view
12:32, 15 August 2009
MaintBot
Fixed text labels
31652
view
11:37, 14 August 2009
MaintBot
Fixed group labels
31185
view
19:28, 13 August 2009
MaintBot
Fixed text labels
30575
view
22:07, 29 July 2009
MaintBot
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
A6H748_BOVIN
GeneProduct
ENSBTAG00000000085 (Ensembl)
A6QPJ8_BOVIN
GeneProduct
ENSBTAG00000021118 (Ensembl)
A9CSS1_BOVIN
GeneProduct
ENSBTAG00000010531 (Ensembl)
AK1A1_BOVIN
GeneProduct
ENSBTAG00000000497 (Ensembl)
AKR1B1
GeneProduct
317748 (Entrez Gene)
AKR1C1
GeneProduct
AKR1C2
GeneProduct
AKR1C3
GeneProduct
782884 (Entrez Gene)
AKR1C4
GeneProduct
282138 (Entrez Gene)
AKR7A2
GeneProduct
511996 (Entrez Gene)
AKR7A3
GeneProduct
788425 (Entrez Gene)
ARY1_BOVIN
GeneProduct
ENSBTAG00000016473 (Ensembl)
Aldo-keto reductase
GeneProduct
Amino acid acyltransferase
GeneProduct
CHST14
GeneProduct
511245 (Entrez Gene)
CHST8
GeneProduct
100271926 (Entrez Gene)
CHST9
GeneProduct
525909 (Entrez Gene)
COMT_BOVIN
GeneProduct
ENSBTAG00000019516 (Ensembl)
CP11A_BOVIN
GeneProduct
ENSBTAG00000006934 (Ensembl)
CP20A_BOVIN
GeneProduct
ENSBTAG00000000851 (Ensembl)
CP2E1_BOVIN
GeneProduct
ENSBTAG00000018365 (Ensembl)
CP2U1_BOVIN
GeneProduct
ENSBTAG00000012972 (Ensembl)
CP51A_BOVIN
GeneProduct
ENSBTAG00000001992 (Ensembl)
CYP11B1
GeneProduct
282422 (Entrez Gene)
CYP11B2
GeneProduct
282423 (Entrez Gene)
CYP17A1
GeneProduct
782561 (Entrez Gene)
CYP19A1
GeneProduct
281740 (Entrez Gene)
CYP21A2
GeneProduct
282425 (Entrez Gene)
CYP27B1
GeneProduct
ENSBTAG00000016906 (Ensembl)
CYP2A13
GeneProduct
CYP2A6
GeneProduct
CYP2A7
GeneProduct
CYP2C18
GeneProduct
535243 (Entrez Gene)
CYP2C19
GeneProduct
510380 (Entrez Gene)
CYP2C8
GeneProduct
CYP2C9
GeneProduct
CYP2D6
GeneProduct
282211 (Entrez Gene)
CYP2F1
GeneProduct
CYP2J2
GeneProduct
521656 (Entrez Gene)
CYP3A43
GeneProduct
CYP3A4
GeneProduct
507988 (Entrez Gene)
CYP3A5
GeneProduct
526682 (Entrez Gene)
CYP3A7
GeneProduct
CYP450
GeneProduct
CYP46A1
GeneProduct
506438 (Entrez Gene)
CYP4F11
GeneProduct
CYP4F12
GeneProduct
CYP4F22
GeneProduct
CYP4F2
GeneProduct
507615 (Entrez Gene)
CYP4F8
GeneProduct
CYP4Z1
GeneProduct
FMO3
GeneProduct
281167 (Entrez Gene)
Flavin monooxygenase
GeneProduct
G3ST1_BOVIN
GeneProduct
ENSBTAG00000014232 (Ensembl)
G3ST3_BOVIN
GeneProduct
ENSBTAG00000002772 (Ensembl)
G3ST4_BOVIN
GeneProduct
ENSBTAG00000015017 (Ensembl)
GLYAT
GeneProduct
281787 (Entrez Gene)
GLYATL1
GeneProduct
GPX1_BOVIN
GeneProduct
ENSBTAG00000004274 (Ensembl)
GPX2
GeneProduct
533088 (Entrez Gene)
GPX3_BOVIN
GeneProduct
ENSBTAG00000043553 (Ensembl)
GPX4_BOVIN
GeneProduct
ENSBTAG00000020778 (Ensembl)
GSHB_BOVIN
GeneProduct
ENSBTAG00000003504 (Ensembl)
GSTA1
GeneProduct
777644 (Entrez Gene)
GSTA2
GeneProduct
GSTA3
GeneProduct
768055 (Entrez Gene)
GSTA4_BOVIN
GeneProduct
ENSBTAG00000004288 (Ensembl)
GSTA5
GeneProduct
521685 (Entrez Gene)
GSTCD_BOVIN
GeneProduct
ENSBTAG00000013927 (Ensembl)
GSTM1
GeneProduct
783879 (Entrez Gene)
GSTM2
GeneProduct
615537 (Entrez Gene)
GSTM4
GeneProduct
GSTM5
GeneProduct
GSTO1
GeneProduct
785216 (Entrez Gene)
GSTP1_BOVIN
GeneProduct
ENSBTAG00000003548 (Ensembl)
GSTT1
GeneProduct
517724 (Entrez Gene)
GSTT2
GeneProduct
2953 (Entrez Gene)
GSTT2B
GeneProduct
Glucuronosyltransferase
GeneProduct
Glutathione transferase
GeneProduct
HNMT_BOVIN
GeneProduct
ENSBTAG00000014432 (Ensembl)
HS3ST3A1
GeneProduct
521959 (Entrez Gene)
HS3ST3B1
GeneProduct
617069 (Entrez Gene)
HS3ST4
GeneProduct
HS6ST2
GeneProduct
517768 (Entrez Gene)
IPI00686912.3
GeneProduct
ENSBTAG00000012998 (Ensembl)
IPI00687876.3
GeneProduct
ENSBTAG00000001144 (Ensembl)
IPI00688083.3
GeneProduct
ENSBTAG00000009093 (Ensembl)
IPI00688142.3
GeneProduct
ENSBTAG00000006157 (Ensembl)
IPI00689284.1
GeneProduct
ENSBTAG00000002803 (Ensembl)
IPI00692810.3
GeneProduct
ENSBTAG00000001658 (Ensembl)
IPI00693008.2
GeneProduct
ENSBTAG00000040000 (Ensembl)
IPI00693768.3
GeneProduct
ENSBTAG00000038369 (Ensembl)
IPI00694081.4
GeneProduct
ENSBTAG00000010644 (Ensembl)
IPI00695153.3
GeneProduct
ENSBTAG00000001448 (Ensembl)
IPI00695412.4
GeneProduct
ENSBTAG00000015647 (Ensembl)
IPI00697335.1
GeneProduct
ENSBTAG00000011014 (Ensembl)
IPI00698655.1
GeneProduct
ENSBTAG00000005287 (Ensembl)
IPI00698855.3
GeneProduct
ENSBTAG00000025760 (Ensembl)
IPI00699039.4
GeneProduct
ENSBTAG00000017595 (Ensembl)
IPI00700522.1
GeneProduct
ENSBTAG00000012212 (Ensembl)
IPI00701497.5
GeneProduct
ENSBTAG00000017701 (Ensembl)
IPI00702562.3
GeneProduct
ENSBTAG00000008707 (Ensembl)
IPI00704129.5
GeneProduct
ENSBTAG00000039319 (Ensembl)
IPI00705153.2
GeneProduct
ENSBTAG00000016685 (Ensembl)
IPI00705496.1
GeneProduct
ENSBTAG00000021408 (Ensembl)
IPI00708458.2
GeneProduct
ENSBTAG00000017391 (Ensembl)
IPI00709378.3
GeneProduct
ENSBTAG00000001692 (Ensembl)
IPI00709424.4
GeneProduct
ENSBTAG00000001299 (Ensembl)
IPI00710606.2
GeneProduct
ENSBTAG00000003131 (Ensembl)
IPI00713683.4
GeneProduct
ENSBTAG00000002765 (Ensembl)
IPI00716297.1
GeneProduct
ENSBTAG00000019249 (Ensembl)
IPI00716958.3
GeneProduct
ENSBTAG00000040290 (Ensembl)
IPI00726067.3
GeneProduct
ENSBTAG00000039065 (Ensembl)
IPI00903985.1
GeneProduct
ENSBTAG00000007654 (Ensembl)
IPI00904186.1
GeneProduct
ENSBTAG00000039973 (Ensembl)
IPI00905203.2
GeneProduct
ENSBTAG00000038275 (Ensembl)
IPI00906116.1
GeneProduct
ENSBTAG00000038084 (Ensembl)
IPI00906608.1
GeneProduct
ENSBTAG00000011584 (Ensembl)
KCAB1_BOVIN
GeneProduct
ENSBTAG00000018465 (Ensembl)
KCAB2_BOVIN
GeneProduct
ENSBTAG00000008125 (Ensembl)
LOC515352
GeneProduct
ENSBTAG00000030847 (Ensembl)
LOC614317
GeneProduct
ENSBTAG00000031364 (Ensembl)
MGST1_BOVIN
GeneProduct
ENSBTAG00000008541 (Ensembl)
MGST2_BOVIN
GeneProduct
ENSBTAG00000021779 (Ensembl)
MGST3_BOVIN
GeneProduct
ENSBTAG00000010265 (Ensembl)
Methyltransferase
GeneProduct
N-acetyltransferase
GeneProduct
NAT13_BOVIN
GeneProduct
ENSBTAG00000007784 (Ensembl)
NAT14_BOVIN
GeneProduct
ENSBTAG00000019051 (Ensembl)
NAT8
GeneProduct
NDST2_BOVIN
GeneProduct
ENSBTAG00000012664 (Ensembl)
NM_001075173.1
GeneProduct
ENSBTAG00000003871 (Ensembl)
NNMT
GeneProduct
NP_001020506.1
GeneProduct
ENSBTAG00000021987 (Ensembl)
NP_001029545.1
GeneProduct
ENSBTAG00000021263 (Ensembl)
NP_001029801.1
GeneProduct
ENSBTAG00000000140 (Ensembl)
NP_001040025.1
GeneProduct
ENSBTAG00000001842 (Ensembl)
NP_001068630.1
GeneProduct
ENSBTAG00000002974 (Ensembl)
NP_001069002.1
GeneProduct
ENSBTAG00000015241 (Ensembl)
NP_001069154.1
GeneProduct
ENSBTAG00000002706 (Ensembl)
NP_001069590.1
GeneProduct
ENSBTAG00000007449 (Ensembl)
NP_001069607.1
GeneProduct
ENSBTAG00000034106 (Ensembl)
NP_001069613.1
GeneProduct
ENSBTAG00000016968 (Ensembl)
NP_001069670.1
GeneProduct
ENSBTAG00000011976 (Ensembl)
NP_001069683.1
GeneProduct
ENSBTAG00000000188 (Ensembl)
NP_001069735.1
GeneProduct
ENSBTAG00000010419 (Ensembl)
NP_001069986.1
GeneProduct
ENSBTAG00000006273 (Ensembl)
NP_001071381.1
GeneProduct
ENSBTAG00000020898 (Ensembl)
NP_001071429.1
GeneProduct
ENSBTAG00000007316 (Ensembl)
NP_001073084.1
GeneProduct
ENSBTAG00000009839 (Ensembl)
NP_001075096.1
GeneProduct
ENSBTAG00000014940 (Ensembl)
NP_001076882.1
GeneProduct
ENSBTAG00000013489 (Ensembl)
NP_001077117.1
GeneProduct
ENSBTAG00000003721 (Ensembl)
NP_001091480.1
GeneProduct
ENSBTAG00000004328 (Ensembl)
NP_001091500.1
GeneProduct
ENSBTAG00000016747 (Ensembl)
NP_001092408.1
GeneProduct
ENSBTAG00000003632 (Ensembl)
NP_001092414.1
GeneProduct
ENSBTAG00000004040 (Ensembl)
NP_001092474.1
GeneProduct
ENSBTAG00000003073 (Ensembl)
NP_001093836.1
GeneProduct
ENSBTAG00000018240 (Ensembl)
NP_001094774.1
GeneProduct
ENSBTAG00000010841 (Ensembl)
NP_001095549.1
GeneProduct
ENSBTAG00000008778 (Ensembl)
NP_001095558.1
GeneProduct
ENSBTAG00000001582 (Ensembl)
NP_001096716.1
GeneProduct
ENSBTAG00000011387 (Ensembl)
NP_777187.1
GeneProduct
ENSBTAG00000026181 (Ensembl)
Q95KN3_BOVIN
GeneProduct
ENSBTAG00000001021 (Ensembl)
ST1A1_BOVIN
GeneProduct
ENSBTAG00000008635 (Ensembl)
ST1B1_BOVIN
GeneProduct
ENSBTAG00000001249 (Ensembl)
ST1E1_BOVIN
GeneProduct
ENSBTAG00000011952 (Ensembl)
SULT1C2
GeneProduct
783020 (Entrez Gene)
SULT1C4
GeneProduct
537919 (Entrez Gene)
SULT2A1
GeneProduct
533560 (Entrez Gene)
SULT2B1
GeneProduct
531192 (Entrez Gene)
Substrate-Aa
Metabolite
Substrate-Ac
Metabolite
Substrate-CH3
Metabolite
Substrate-Gl
Metabolite
Substrate-NH2
Metabolite
Substrate-O-R
Metabolite
Substrate-OH
Metabolite
Substrate-SG
Metabolite
Substrate-SH
Metabolite
Substrate-SO3H
Metabolite
Substrate=O
Metabolite
Sulfotransferase
GeneProduct
TPMT_BOVIN
GeneProduct
ENSBTAG00000019300 (Ensembl)
UGT1A10
GeneProduct
UGT1A1
GeneProduct
751790 (Entrez Gene)
UGT1A3
GeneProduct
UGT1A4
GeneProduct
UGT1A5
GeneProduct
UGT1A6
GeneProduct
286792 (Entrez Gene)
UGT1A7
GeneProduct
UGT1A9
GeneProduct
UGT2A1
GeneProduct
UGT2A2
GeneProduct
UGT2B11
GeneProduct
100138004 (Entrez Gene)
UGT2B15
GeneProduct
540544 (Entrez Gene)
UGT2B17
GeneProduct
540615 (Entrez Gene)
UGT2B28
GeneProduct
UGT2B4
GeneProduct
615303 (Entrez Gene)
UGT2B7
GeneProduct
XR_027890.2
GeneProduct
ENSBTAG00000007115 (Ensembl)
Xenobiotic substrate
Metabolite
Annotated Interactions
No annotated interactions
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Try the New WikiPathways
View approved pathways at the new wikipathways.org.Quality Tags
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External references
DataNodes
Annotated Interactions
No annotated interactions