Fin development (Danio rerio)

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56532, 785595592, 75257588761Pitx genesFgf genesosr genesBmp genesWnt genesTbx genesretinoic acidfibinPitx1osr2gdf5wnt8cchordincx43pea3evx1pdlim7etv5aTbx4wnt3aZns5 Antibodywnt2bfgf24bmp2braldh2Tbx5Pitx2fgf10osr1ptc1441517777777777hoxd13a7and1shhaermfgf8agli3and2


Description

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Ontology Terms

 

Bibliography

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  1. Zhang J, Wagh P, Guay D, Sanchez-Pulido L, Padhi BK, Korzh V, Andrade-Navarro MA, Akimenko MA; ''Loss of fish actinotrichia proteins and the fin-to-limb transition.''; Nature, 2010 PubMed Europe PMC Scholia
  2. Camarata T, Snyder D, Schwend T, Klosowiak J, Holtrup B, Simon HG; ''Pdlim7 is required for maintenance of the mesenchymal/epidermal Fgf signaling feedback loop during zebrafish pectoral fin development.''; BMC Dev Biol, 2010 PubMed Europe PMC Scholia
  3. Tanaka M; ''Molecular and evolutionary basis of limb field specification and limb initiation.''; Dev Growth Differ, 2013 PubMed Europe PMC Scholia
  4. Tanaka M, Hale LA, Amores A, Yan YL, Cresko WA, Suzuki T, Postlethwait JH; ''Developmental genetic basis for the evolution of pelvic fin loss in the pufferfish Takifugu rubripes.''; Dev Biol, 2005 PubMed Europe PMC Scholia
  5. Wakahara T, Kusu N, Yamauchi H, Kimura I, Konishi M, Miyake A, Itoh N; ''Fibin, a novel secreted lateral plate mesoderm signal, is essential for pectoral fin bud initiation in zebrafish.''; Dev Biol, 2007 PubMed Europe PMC Scholia
  6. Gibert Y, Gajewski A, Meyer A, Begemann G; ''Induction and prepatterning of the zebrafish pectoral fin bud requires axial retinoic acid signaling.''; Development, 2006 PubMed Europe PMC Scholia
  7. Sims K Jr, Eble DM, Iovine MK; ''Connexin43 regulates joint location in zebrafish fins.''; Dev Biol, 2009 PubMed Europe PMC Scholia
  8. Neto A, Mercader N, Gómez-Skarmeta JL; ''The Osr1 and Osr2 genes act in the pronephric anlage downstream of retinoic acid signaling and upstream of Wnt2b to maintain pectoral fin development.''; Development, 2012 PubMed Europe PMC Scholia
  9. Roehl H, Nüsslein-Volhard C; ''Zebrafish pea3 and erm are general targets of FGF8 signaling.''; Curr Biol, 2001 PubMed Europe PMC Scholia
  10. Schulte CJ, Allen C, England SJ, Juárez-Morales JL, Lewis KE; ''Evx1 is required for joint formation in zebrafish fin dermoskeleton.''; Dev Dyn, 2011 PubMed Europe PMC Scholia
  11. Mao J, McGlinn E, Huang P, Tabin CJ, McMahon AP; ''Fgf-dependent Etv4/5 activity is required for posterior restriction of Sonic Hedgehog and promoting outgrowth of the vertebrate limb.''; Dev Cell, 2009 PubMed Europe PMC Scholia
  12. Quint E, Smith A, Avaron F, Laforest L, Miles J, Gaffield W, Akimenko MA; ''Bone patterning is altered in the regenerating zebrafish caudal fin after ectopic expression of sonic hedgehog and bmp2b or exposure to cyclopamine.''; Proc Natl Acad Sci U S A, 2002 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
87490view01:39, 25 July 2016AlexanderPicoOntology Term : 'regulatory pathway' added !
87489view01:39, 25 July 2016AlexanderPicoOntology Term : 'growth factor signaling pathway' added !
85389view10:04, 11 May 2016EgonwReplaced a mim-conversion with Arrow.
84693view20:26, 15 March 2016KhanspersQuick edit to datanode annotation or property
84692view20:25, 15 March 2016KhanspersQuick edit to datanode annotation or property
79810view16:46, 16 April 2015Mkutmonfixed unconnected line
78355view09:56, 7 January 2015MaintBotadded missing graphIds
77434view12:37, 8 September 2014Mkutmonconnected lines, added some references
72926view05:09, 16 December 2013LmjacksonFixing Layout
72925view22:14, 15 December 2013Josh.hanscomGilbert et al. 2006
72920view21:07, 15 December 2013LmjacksonNeto, 2012 paper
72919view21:06, 15 December 2013LmjacksonPeriodical save, work in progress
72915view07:16, 15 December 2013Josh.hanscomSpecify description
72914view07:15, 15 December 2013Josh.hanscomPart of Wakahara et al. 2006
72913view07:11, 15 December 2013Josh.hanscomPart of Wakahara et al. 2006
72808view18:25, 9 December 2013LmjacksonGrem1
72796view16:31, 9 December 2013LmjacksonFixing connections
72795view16:30, 9 December 2013LmjacksonAdded Camarata et al., 2010
72793view16:26, 9 December 2013LmjacksonPeriodical save, work in progress
72792view16:15, 9 December 2013LmjacksonPeriodical save, work in progress
72788view16:05, 9 December 2013LmjacksonPeriodical save, work in progress
72787view15:44, 9 December 2013LmjacksonPeriodical save, work in progress
72786view15:34, 9 December 2013LmjacksonPeriodical save, work in progress
72776view04:18, 9 December 2013Josh.hanscomRoehl et al. 2001 added
72745view15:59, 4 December 2013LmjacksonFixing group boxes
72742view05:36, 4 December 2013LmjacksonAdded tbx, pitx, bmp, wnt, and osr genes
72741view05:28, 4 December 2013LmjacksonPeriodical save, work in progress
72740view05:18, 4 December 2013LmjacksonPeriodical save, work in progress
72739view05:08, 4 December 2013LmjacksonPeriodical save, work in progress
72738view04:58, 4 December 2013LmjacksonPeriodical save, work in progress
72737view04:48, 4 December 2013LmjacksonPeriodical save, work in progress
72736view04:38, 4 December 2013LmjacksonPeriodical save, work in progress
72735view03:37, 4 December 2013LmjacksonPeriodical save, work in progress
72734view03:27, 4 December 2013LmjacksonPeriodical save, work in progress
72700view18:25, 2 December 2013Josh.hanscomConnected arrows
72694view13:53, 2 December 2013Josh.hanscomAdded part of Mao et al. 2009
72527view03:07, 19 November 2013Josh.hanscomEdited Zns5:cx43
72485view05:02, 18 November 2013LmjacksonQuint et al., 2002
72484view04:55, 18 November 2013LmjacksonPeriodical save, work in progress
72483view04:50, 18 November 2013LmjacksonZhang et al., 2010
72482view04:38, 18 November 2013LmjacksonZhang et al., 2010 genes added
72481view04:26, 18 November 2013Josh.hanscomAdded Zns5 and cx43
72480view04:19, 18 November 2013Josh.hanscomAdded evx1 and gdf5
72413view19:12, 13 November 2013JoshloebsSpecify description
72412view19:11, 13 November 2013Luke.fuhrman
72411view19:04, 13 November 2013Josh.hanscomSpecify description
72410view18:53, 13 November 2013Josh.hanscomPeriodical save, work in progress
72409view18:50, 13 November 2013Josh.hanscomSpecify description
72408view18:48, 13 November 2013Josh.hanscomSpecify description
72407view18:46, 13 November 2013Josh.hanscomSpecify description

External references

DataNodes

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NameTypeDatabase referenceComment
Pitx1GeneProduct
Pitx2GeneProduct
Tbx4GeneProduct
Tbx5GeneProduct
Zns5 Antibody
and1GeneProductZDB-GENE-030131-9105 (ZFIN)
and2GeneProductZDB-GENE-041105-2 (ZFIN)
bmp2bGeneProduct
chordinGeneProduct
cx43GeneProductZDB-GENE-991105-4 (ZFIN)
ermGeneProduct
etv5aGeneProductZDB-GENE-030131-9572 (ZFIN)
evx1GeneProductZDB-GENE-980526-364 (ZFIN)
fgf10GeneProduct
fgf24GeneProduct
fgf8aGeneProductZDB-GENE-990415-72 (ZFIN)
fibinGeneProduct
gdf5GeneProductZDB-GENE-990415-39 (ZFIN)
gli3GeneProductZDB-GENE-041111-162 (ZFIN)
hoxd13aGeneProductZDB-GENE-990415-119 (ZFIN)
osr1GeneProduct
osr2GeneProduct
pdlim7GeneProduct
pea3GeneProduct
ptc1GeneProduct
raldh2GeneProductZebrafish mutants for retinaldehyde dehydrogenase 2 (raldh2) lack pectoral fin buds
retinoic acid
shhaGeneProductZDB-GENE-980526-166 (ZFIN)
wnt2bGeneProduct
wnt3aGeneProduct
wnt8cGeneProduct

Annotated Interactions

No annotated interactions

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