Cadmium and glutathione (Arabidopsis thaliana)
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Egonw
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CCH
ATX1
Cd
GSH biosynthesis
72h
48h
24h
2h
...
transcript level
significant increase
significant decrease
5 µM Cd
glycine
GSH
APX1
Cd
GSH1
MDHAR
glutamate
PC
gamma-EC
cysteine
AsA
GSH
GSH2
Cd chelation
Cd
GSH
PCS1
Cd
Cd
Cd
Cd
Cd
MDHA
APX2
DHA
GSSG
GSH
DHAR
NADPH
NADP+
H2O2
2 H2O
GR1
AsA-GSH cycle
MSD1
FSD1
CCS
CSD1
CSD2
miR398a
miR398b/c
activity level
MnSOD
FeSOD
CuZnSOD
SOD regulation
GSSG
GSH
leaf
root
10 µM Cd
LEGEND
Description
No description
Comments
kinetics
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Quality Tags
Ontology Terms
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Bibliography
Jozefczak M, Keunen E, Schat H, Bliek M, Hernández LE, Carleer R, Remans T, Bohler S, Vangronsveld J, Cuypers A; ''Differential response of Arabidopsis leavesand roots to cadmium: glutathione-related chelating capacity vs antioxidant capacity.''; Plant Physiol Biochem, 2014
PubMed
Europe PMC
Scholia
History
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Revision
Action
Time
User
Comment
107043
view
14:11, 17 September 2019
MaintBot
ChEBI identifier normalization
105897
view
11:36, 16 August 2019
Mkutmon
HMDB identifier normalization
82711
view
09:46, 23 October 2015
Egonw
Added the paper from which the figure was digitized to the reference list.
82710
view
09:39, 23 October 2015
Egonw
Fixed the identifier for NADP+ (the HMDB id for glutathion was used).
79443
view
06:51, 22 March 2015
Egonw
Removed Entrez Gene xrefs where gene names where used and of which the genes are given by another gene code and identifier too.
77262
view
01:04, 9 August 2014
AlexanderPico
one more shape sent to back
77261
view
01:03, 9 August 2014
AlexanderPico
Set bounding shapes behind datanodes
77260
view
00:56, 9 August 2014
AlexanderPico
Modified description
77206
view
16:14, 5 August 2014
Marijke Jozefczak
Modified description
77205
view
16:11, 5 August 2014
Marijke Jozefczak
Modified description
74481
view
11:29, 25 April 2014
Marijke Jozefczak
no legend
74132
view
05:54, 1 April 2014
Egonw
Removed a non-existing HMDB ID and cannot figure out based on the name 'DHA' what it should be.
74130
view
05:22, 1 April 2014
Egonw
Replaced an unknown HMDB identifier (not on their website) with the ChEBI one.
73612
view
20:35, 4 February 2014
Marijke Jozefczak
Modified title
73611
view
20:34, 4 February 2014
Marijke Jozefczak
PP
72205
view
11:49, 27 October 2013
Egonw
Ontology Term : 'cellular detoxification pathway' added !
71886
view
19:25, 21 October 2013
Marijke Jozefczak
New pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
2 H2O
Metabolite
HMDB02111 (HMDB)
APX1
GeneProduct
AT1G07890 (Ensembl)
APX2
GeneProduct
AT3G09640 (Ensembl)
ATX1
GeneProduct
AT1G66240 (Ensembl)
AsA
Metabolite
HMDB00044 (HMDB)
CCH
GeneProduct
AT3G56240 (Ensembl)
CCS
GeneProduct
AT1G12520 (Ensembl)
CSD1
GeneProduct
AT1G08830 (Ensembl)
CSD2
GeneProduct
AT2G28190 (Ensembl)
Cd
Metabolite
HMDB03638 (HMDB)
CuZnSOD
Protein
CuZnSOD (Entrez Gene)
DHA
Metabolite
HMDB13004 (HMDB)
DHAR
Protein
GO:0045174 (GeneOntology)
FSD1
GeneProduct
AT4G25100 (Ensembl)
FeSOD
Protein
FeSOD (Entrez Gene)
GR1
GeneProduct
AT3G24170 (Ensembl)
GSH1
GeneProduct
828409 (Entrez Gene)
GSH2
GeneProduct
AT5G27380 (Ensembl)
GSH
Metabolite
HMDB00125 (HMDB)
GSSG
Metabolite
HMDB03337 (HMDB)
H2O2
Metabolite
HMDB03125 (HMDB)
MDHA
Metabolite
CHEBI:16504 (ChEBI)
MDHAR
Protein
GO:0016656 (GeneOntology)
MSD1
GeneProduct
820263 (Entrez Gene)
MnSOD
MnSOD (Entrez Gene)
NADP+
Metabolite
HMDB00125 (HMDB)
NADPH
Metabolite
HMDB00221 (HMDB)
PC
Metabolite
60836 (ChEBI)
PCS1
Protein
Q9S7Z3 (Uniprot-TrEMBL)
cysteine
Metabolite
HMDB00574 (HMDB)
gamma-EC
Metabolite
HMDB01049 (HMDB)
glutamate
Metabolite
HMDB00148 (HMDB)
glycine
Metabolite
HMDB00123 (HMDB)
miR398a
GeneProduct
AT2G03445 (Ensembl)
miR398b/c
GeneProduct
AT5G14545 (Ensembl)
Annotated Interactions
No annotated interactions
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DataNodes
Annotated Interactions
No annotated interactions