Gonadotropin-releasing hormone (GnRH) signaling (Bos taurus)

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1, 2ER+pGonadothropins gene expression & Secration+p+pMAPK11ADCY4MAPK1DNAPRKACAPKCMAP2K3PLD1cAMPMAP2K2Ca+2PA,PEMAPK Signaling PathwayCALM2GsMAP2K7PLCB1ELK1PRKXAAKRASITPR1CACNA1CCACNA1DPLD2LHخ²Ca+2MAPK10Grb2MT1c-JUNADCY6PLCB4MAP2K4MAPK3CAMK2BMAPK12Cytokine-cytokine receptor interaction pathwayMAPK13MMP2CREBPLA2G4BADCY5ITPR3PLA2G4ACACNA1SADCY2PLA2G4FNRASGNRHRBMKCALM3MAP3K4Pyk2DNAMAP3K2MAPK14ADCY8خ±GSUITPR2IP3CALML6PLCB2FSHخ²MAPK9SOS1ADCY3ADCY9Neuroactive ligand-receptor interactionPathwayGNRH1MAP2K1ADCY1PRKACBHRASPLCB3MAP3K3GNRH2CALMCAMK2GDNACDC42PLA2G4EGNA11Calcium signaling pathwayMEKKMAP3K1DAGSRCCAMK2ARAF1EGFRADCY7HB-EGFMAP2K6CAMK2DSOS2CALML5CACNA1FMAPK8PLA2G4DGNAQCALM1+pLHخ²+p+p+p+p


Description

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Quality Tags

Ontology Terms

 

Bibliography

  1. Kim HH; ''Regulation of gonadotropin-releasing hormone gene expression.''; Semin Reprod Med, 2007 PubMed Europe PMC Scholia
  2. Widmann P, Reverter A, Fortes MR, Weikard R, Suhre K, Hammon H, Albrecht E, Kuehn C; ''A systems biology approach using metabolomic data reveals genes and pathways interacting to modulate divergent growth in cattle.''; BMC Genomics, 2013 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
123067view04:19, 23 June 2022EgonwMade a pathway clickable
107056view14:14, 17 September 2019MaintBotChEBI identifier normalization
87581view02:24, 25 July 2016AlexanderPicoOntology Term : 'signaling pathway' added !
87580view02:24, 25 July 2016AlexanderPicoOntology Term : 'gonadotropin releasing neuron' added !
87360view09:39, 22 July 2016MaintBotadded missing graphids
87329view11:26, 21 July 2016MkutmonReverted to version '11:22, 21 July 2016' by Mkutmon
87328view11:25, 21 July 2016MaintBotadded missing graphids
87327view11:22, 21 July 2016MkutmonReverted to version '16:21, 10 November 2015' by Mkutmon
87326view11:16, 21 July 2016MaintBotadded missing graphids
82869view16:21, 10 November 2015JmeliusCorrect outdated id
82851view20:18, 9 November 2015EgonwRemoved a non-numeric Entrez gene (and MEKK is not found in Entrez Gene for cow).
79023view08:25, 25 February 2015Mkutmonfixed xref for MAPK1
79022view08:23, 25 February 2015Mkutmonfixed special character
79021view08:22, 25 February 2015Mkutmonfixed xrefs and special characters
79015view14:28, 24 February 2015ZariModified description
79014view14:27, 24 February 2015ZariModified description
79013view14:25, 24 February 2015ZariNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
AAMetabolite15843 (ChEBI)
ADCY1GeneProduct281601آ آ  (Entrez Gene)
ADCY2GeneProduct510708آ آ  (Entrez Gene)
ADCY3GeneProduct535603آ آ  (Entrez Gene)
ADCY4GeneProduct788151آ آ  (Entrez Gene)
ADCY5GeneProduct505740آ آ  (Entrez Gene)
ADCY6GeneProduct509936آ آ  (Entrez Gene)
ADCY7GeneProduct281603آ آ  (Entrez Gene)
ADCY8GeneProduct535017آ آ  (Entrez Gene)
ADCY9GeneProduct525482آ آ  (Entrez Gene)
BMKGeneProduct537703آ آ  (Entrez Gene)
CACNA1CGeneProduct408015آ آ  (Entrez Gene)
CACNA1DGeneProduct408013آ آ  (Entrez Gene)
CACNA1FGeneProductآ آ 509779آ آ  (Entrez Gene)
CACNA1SGeneProduct100337204آ آ  (Entrez Gene)
CALM1GeneProduct617095آ آ  (Entrez Gene)
CALM2GeneProduct100297344آ آ  (Entrez Gene)
CALMGeneProduct326597آ آ  (Entrez Gene)
CALM3GeneProduct520277آ آ  (Entrez Gene)
CALML5GeneProduct520404آ آ  (Entrez Gene)
CALML6GeneProduct617412آ آ  (Entrez Gene)
CAMK2AGeneProduct530719آ آ  (Entrez Gene)
CAMK2BGeneProduct525416آ آ  (Entrez Gene)
CAMK2DGeneProduct532713آ آ  (Entrez Gene)
CAMK2GGeneProduct282162آ آ  (Entrez Gene)
CDC42GeneProduct532712آ آ  (Entrez Gene)
CREBGeneProduct509107آ آ  (Entrez Gene)
Ca+2Metabolite29108 (ChEBI)
Calcium signaling pathwayPathway
Cytokine-cytokine receptor interaction pathwayPathway
DAGMetabolite18035 (ChEBI)
DNAMetabolite
EGFRGeneProduct407217آ آ  (Entrez Gene)
ELK1GeneProduct786886آ آ  (Entrez Gene)
FSHخ²GeneProduct281171آ آ  (Entrez Gene)
GNA11GeneProduct281788آ آ  (Entrez Gene)
GNAQGeneProduct536654آ آ  (Entrez Gene)
GNRH1GeneProduct768325آ آ  (Entrez Gene)
GNRH2GeneProduct100848664 (Entrez Gene)
GNRHRGeneProduct281798آ آ  (Entrez Gene)
Grb2GeneProduct535298آ آ  (Entrez Gene)
GsGeneProduct281793آ آ  (Entrez Gene)
HB-EGFGeneProduct522921آ آ  (Entrez Gene)
HRASGeneProduct100298939آ آ  (Entrez Gene)
IP3Metabolite16595 (ChEBI)
ITPR1GeneProduct317697آ آ  (Entrez Gene)
ITPR2GeneProduct281878آ آ  (Entrez Gene)
ITPR3GeneProduct281879آ آ  (Entrez Gene)
KRASGeneProduct541140آ آ  (Entrez Gene)
LHخ²GeneProduct280839آ آ  (Entrez Gene)
LHخ²GeneProduct786429آ آ  (Entrez Gene)
MAP2K1GeneProduct533199آ آ  (Entrez Gene)
MAP2K2GeneProduct510434آ آ  (Entrez Gene)
MAP2K3GeneProduct516039آ آ  (Entrez Gene)
MAP2K4GeneProduct526469آ آ  (Entrez Gene)
MAP2K6GeneProduct286883آ آ  (Entrez Gene)
MAP2K7GeneProduct787278آ آ آ  (Entrez Gene)
MAP3K1GeneProduct523962آ آ  (Entrez Gene)
MAP3K2GeneProduct504592آ آ آ آ  (Entrez Gene)
MAP3K3GeneProduct508943آ آ  (Entrez Gene)
MAP3K4GeneProduct511779آ آ  (Entrez Gene)
MAPK Signaling PathwayPathwayWP998 (WikiPathways)
MAPK10GeneProduct534125آ آ  (Entrez Gene)
MAPK11GeneProduct618906آ آ  (Entrez Gene)
MAPK12GeneProduct512943آ آ  (Entrez Gene)
MAPK1GeneProduct327672آ آ آ  (Entrez Gene)
MAPK13GeneProduct535327آ آ  (Entrez Gene)
MAPK14GeneProduct534492آ آ  (Entrez Gene)
MAPK3GeneProduct531391آ آ  (Entrez Gene)
MAPK8GeneProduct539941آ آ آ  (Entrez Gene)
MAPK9GeneProduct537631آ آ  (Entrez Gene)
MEKKGeneProductMAP3K1 (Entrez Gene)
MMP2GeneProduct4313آ آ  (Entrez Gene)
MT1GeneProduct4323آ آ  (Entrez Gene)
NRASGeneProduct506322آ آ  (Entrez Gene)
Neuroactive ligand-receptor interactionPathwayPathway
PA,PEMetabolite16337 (ChEBI)
PKCGeneProduct
PLA2G4AGeneProduct525072آ آ آ آ  (Entrez Gene)
PLA2G4BGeneProduct505485آ آ آ  (Entrez Gene)
PLA2G4DGeneProduct531209آ آ  (Entrez Gene)
PLA2G4EGeneProduct526364آ آ  (Entrez Gene)
PLA2G4FGeneProduct522866آ آ  (Entrez Gene)
PLCB1GeneProduct287026آ آ  (Entrez Gene)
PLCB2GeneProduct508888آ آ  (Entrez Gene)
PLCB3GeneProduct515669آ آ  (Entrez Gene)
PLCB4GeneProduct281985آ آ  (Entrez Gene)
PLD1GeneProduct522159آ آ آ آ  (Entrez Gene)
PLD2GeneProduct514554آ آ آ  (Entrez Gene)
PRKACAGeneProduct282322آ آ  (Entrez Gene)
PRKACBGeneProduct282323آ آ  (Entrez Gene)
PRKXGeneProduct505773آ آ  (Entrez Gene)
Pyk2GeneProduct541008آ آ  (Entrez Gene)
RAF1GeneProduct521196آ آ آ آ  (Entrez Gene)
SOS1GeneProduct537682آ آ  (Entrez Gene)
SOS2GeneProduct100138040آ آ  (Entrez Gene)
SRCGeneProduct535742آ آ  (Entrez Gene)
c-JUNGeneProduct280831آ آ  (Entrez Gene)
cAMPMetabolite17489 (ChEBI)
خ±GSUGeneProduct280749آ آ  (Entrez Gene)

Annotated Interactions

No annotated interactions

Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP2901"
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