TGF-beta signaling pathway (Drosophila melanogaster)
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Co-Smads
R-Smads
Repressors
Rsmads
Cofactor
HOMOLOGY MAPP
TGFb
Accessory receptors:
Cofactors
ligands:
Co-smads
FKBP1A
SMAD4
EP300
IFNG
RUNX2
SPP1
FST
SMAD2
BAMBI
JUN
SMAD1
MAPK9
TNF
LTBP1
TGFBR3
STAT1
MAPK3
ZNF423
NFKB1
SMAD2
ZFHX1B
SKIL
SMAD1
ITGB6
SMAD6
THBS1
RUNX3
LIF
LEF1
TGFBR2
ZFYVE9
TGFBR1
SMAD3
SMAD7
NOG
TGFB1
EGF
STAT3
SMAD5
TGFBR2
CTNNB1
BMP4
INHBA
BMP4
SMAD9
TGFB1
TGFBR1
SERPINE1
FOS
ENG
FOXH1
WNT1
TGIF
TNF
HRAS
CREBBP
TFE3
JAK1
SKI
Description
No description
Comments
GenMAPP notes
Further reading: Massague J. et al. Cell. 2000 Oct 13;103(2):295-309. , and Nat Rev Mol Cell Biol. 2000 Dec 1(3):169-78.
GenMAPP remarks
edited by: Nathan Salomonis
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Compare
Revision
Action
Time
User
Comment
116496
view
10:30, 7 May 2021
Eweitz
Modified title
79499
view
15:44, 23 March 2015
Ryan.miller
79363
view
19:20, 21 March 2015
Khanspers
update schema
79362
view
19:19, 21 March 2015
Khanspers
Reverted to version '11:50, 26 June 2013' by
Khanspers
68713
view
21:39, 6 July 2013
MaintBot
Updated to 2013 gpml schema
67693
view
11:50, 26 June 2013
Ddigles
Ontology Term : 'transforming growth factor-beta superfamily mediated signaling pathway' added !
40881
view
22:34, 1 March 2011
MaintBot
Removed redundant pathway information and comments
21161
view
11:30, 14 November 2008
MaintBot
[[Pathway:Drosophila melanogaster:TGF Beta Signaling Pathway]] moved to [[Pathway:WP230]]: Moved to stable identifier
8525
view
14:02, 7 January 2008
MaintBot
Added to category $category
8523
view
14:02, 7 January 2008
N.Gal
Uploaded new pathway
External references
DataNodes
View all...
Name
Type
Database reference
Comment
BAMBI
GeneProduct
BMP4
GeneProduct
CREBBP
GeneProduct
CTNNB1
GeneProduct
31151 (Entrez Gene)
EGF
GeneProduct
ENG
GeneProduct
EP300
GeneProduct
43856 (Entrez Gene)
FKBP1A
GeneProduct
37214 (Entrez Gene)
FOS
GeneProduct
FOXH1
GeneProduct
FST
GeneProduct
2768836 (Entrez Gene)
HRAS
GeneProduct
IFNG
GeneProduct
INHBA
GeneProduct
ITGB6
GeneProduct
JAK1
GeneProduct
JUN
GeneProduct
LEF1
GeneProduct
LIF
GeneProduct
LTBP1
GeneProduct
MAPK3
GeneProduct
MAPK9
GeneProduct
NFKB1
GeneProduct
NOG
GeneProduct
RUNX2
GeneProduct
33051 (Entrez Gene)
RUNX3
GeneProduct
SERPINE1
GeneProduct
SKI
GeneProduct
34085 (Entrez Gene)
SKIL
GeneProduct
SMAD1
GeneProduct
33529 (Entrez Gene)
SMAD2
GeneProduct
31738 (Entrez Gene)
SMAD3
GeneProduct
SMAD4
GeneProduct
43725 (Entrez Gene)
SMAD5
GeneProduct
SMAD6
GeneProduct
SMAD7
GeneProduct
42059 (Entrez Gene)
SMAD9
GeneProduct
SPP1
GeneProduct
STAT1
GeneProduct
STAT3
GeneProduct
TFE3
GeneProduct
TGFB1
GeneProduct
TGFBR1
GeneProduct
35900 (Entrez Gene)
TGFBR2
GeneProduct
TGFBR3
GeneProduct
TGIF
GeneProduct
THBS1
GeneProduct
there are 5 types of tsp
TNF
GeneProduct
WNT1
GeneProduct
34009 (Entrez Gene)
ZFHX1B
GeneProduct
ZFYVE9
GeneProduct
44263 (Entrez Gene)
ZNF423
GeneProduct
36609 (Entrez Gene)
Annotated Interactions
No annotated interactions
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Try the New WikiPathways
View approved pathways at the new wikipathways.org.Quality Tags
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External references
DataNodes
Annotated Interactions
No annotated interactions