Complement and coagulation cascades (Rattus norvegicus)

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Vascular injuryAntibody/antigencomplexC5aExtrinsic pathwayDegredationCell adhesion,migration,proliferation, etc.Zymosaninsulin, etc.MediatorsAlternative PathwayCoagulation Cascadefibrin polymerFibrinmonomerC3b/BbC3ConvertaseFibrinolytic systemPlatelet, monocyte,lymphocyte,endothelial cells,smooth muscle cellsactivation etc.Complement CascadeCollagen,basement membrane,activated platelets, etc.C4b/2aClotCell adhesion,migration,proliferation, etc.Cell lysisClassical Pathwayfibrin degredationproductsC4aC3b/4b, C3b, C3dmembrane attack complexCross-linkedMuscle contraction,Chemotaxis,Phagocyte recruitment,Inflammation, etc.C3aC3bLectin PathwayKinin kallikrein systemF10PlaurProcThbdC1sC9BradykininC1rC3F12C1qbPlatPlgSerpinc1RGD:735225McpBdkrb1CfhF2F11Masp2CrryCd59C5r1F3C2PlauF5Serpinf2A2mHcRGD:727845TfpiC8bCfiSerpind1Kng1C4bpKlkb1C4aH2-BfRGD:621759F7Cpb2F2rF9Pros1Masp1F13bSerpina1AdnC7Mbl1Daf1Serpina5Cr2FgbC6CrryC1qgSerpine1C3ar1Daf2C1qa


Description

No description

Comments

GenMAPP notes 
http://www.genome.jp/dbget-bin/get pathway?org name=mmu&mapno=04610
GenMAPP remarks 
Adapted from KEGG (see notes)

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
116949view10:05, 16 May 2021EweitzModified title
106999view13:45, 17 September 2019MaintBotHMDB identifier normalization
91912view21:08, 3 April 2017KhanspersModified description
91911view21:07, 3 April 2017Khanspersremoved GenMAPP comments
83032view02:42, 18 November 2015Mkutmonfix outdated identifier
79832view09:22, 17 April 2015EgonwReplaced a gene name with its Entrez Gene identifier.
79658view17:51, 1 April 2015Khanspersreplacing non-numeric Entrez
69384view18:57, 8 July 2013MaintBotUpdated to 2013 gpml schema
67785view15:14, 26 June 2013DdiglesOntology Term : 'complement system pathway' added !
67125view10:09, 26 June 2013Christine ChichesterOntology Term : 'coagulation cascade pathway' added !
41700view02:37, 2 March 2011MaintBotRemoved redundant pathway information and comments
38702view19:27, 23 September 2010AlexanderPico
34319view22:12, 9 December 2009KhanspersAdded connectors
34313view22:09, 9 December 2009KhanspersPeriodical save, work in progress
34283view21:59, 9 December 2009KhanspersPeriodical save, work in progress
34254view21:48, 9 December 2009KhanspersPeriodical save, work in progress
34230view21:37, 9 December 2009KhanspersPeriodical save, work in progress
22596view13:44, 14 November 2008ThomasChanged pathway title (was duplicate of WP81)
21830view11:32, 14 November 2008MaintBot[[Pathway:Rattus norvegicus:Complement and Coagulation Cascades KEGG]] moved to [[Pathway:WP547]]: Moved to stable identifier
7976view13:46, 7 January 2008MaintBot[[Pathway:Rat:Complement and Coagulation Cascades KEGG]] moved to [[Pathway:Rattus norvegicus:Complement and Coagulation Cascades KEGG]]: Renaming species
7612view16:04, 18 December 2007MaintBotfixed category names
7469view12:42, 4 November 2007MaintBotAdded categories to GPML
6528view22:19, 22 May 2007169.230.77.174gpml file for [[Rat:Complement_and_Coagulation_Cascades_KEGG]]

External references

DataNodes

View all...
NameTypeDatabase referenceComment
A2mGeneProduct24153 (Entrez Gene)
AdnGeneProduct54249 (Entrez Gene)
Bdkrb1GeneProduct81509 (Entrez Gene)
BradykininMetaboliteHMDB04246 (HMDB)
C1qaGeneProduct298566 (Entrez Gene)
C1qbGeneProduct29687 (Entrez Gene)
C1qgGeneProduct362634 (Entrez Gene)
C1rGeneProduct312705 (Entrez Gene)
C1sGeneProduct192262 (Entrez Gene)
C2GeneProduct24231 (Entrez Gene)
C3GeneProduct24232 (Entrez Gene)
C3ar1GeneProduct84007 (Entrez Gene)
C4aGeneProduct24233 (Entrez Gene)
C4bpGeneProduct24234 (Entrez Gene)
C5r1GeneProduct113959 (Entrez Gene)
C6GeneProduct24237 (Entrez Gene)
C7GeneProduct117517 (Entrez Gene)
C8bGeneProduct313421 (Entrez Gene)
C9GeneProduct117512 (Entrez Gene)
Cd59GeneProduct25407 (Entrez Gene)
CfhGeneProduct155012 (Entrez Gene)
CfiGeneProduct79126 (Entrez Gene)
Cpb2GeneProduct113936 (Entrez Gene)
Cr2GeneProduct289395 (Entrez Gene)
CrryGeneProduct54243 (Entrez Gene)
Daf1GeneProduct64036 (Entrez Gene)
Daf2GeneProduct
F10GeneProduct29243 (Entrez Gene)
F11GeneProduct290757 (Entrez Gene)
F12GeneProductF12 (Entrez Gene)
F13bGeneProduct289055 (Entrez Gene)
F2GeneProduct29251 (Entrez Gene)
F2rGeneProduct25439 (Entrez Gene)
F3GeneProduct25584 (Entrez Gene)
F5GeneProduct304929 (Entrez Gene)
F7GeneProduct260320 (Entrez Gene)
F9GeneProduct24946 (Entrez Gene)
FgbGeneProduct24366 (Entrez Gene)
H2-BfGeneProduct294257 (Entrez Gene)
HcGeneProduct24441 (Entrez Gene)
Klkb1GeneProduct25048 (Entrez Gene)
Kng1GeneProduct24903 (Entrez Gene)
Masp1GeneProduct64023 (Entrez Gene)
Masp2GeneProduct64459 (Entrez Gene)
Mbl1GeneProduct24548 (Entrez Gene)
McpGeneProduct29333 (Entrez Gene)
PlatGeneProduct25692 (Entrez Gene)
PlauGeneProduct25619 (Entrez Gene)
PlaurGeneProduct50692 (Entrez Gene)
PlgGeneProduct85253 (Entrez Gene)
ProcGeneProduct25268 (Entrez Gene)
Pros1GeneProduct81750 (Entrez Gene)
RGD:621759GeneProduct116669 (Entrez Gene)
RGD:727845GeneProduct302470 (Entrez Gene)
RGD:735225GeneProduct295703 (Entrez Gene)
Serpina1GeneProduct24648 (Entrez Gene)
Serpina5GeneProduct65051 (Entrez Gene)
Serpinc1GeneProduct304917 (Entrez Gene)
Serpind1GeneProduct79224 (Entrez Gene)
Serpine1GeneProduct24617 (Entrez Gene)
Serpinf2GeneProduct287527 (Entrez Gene)
TfpiGeneProduct29436 (Entrez Gene)
ThbdGeneProduct83580 (Entrez Gene)

Annotated Interactions

No annotated interactions
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