Brassinosteroid biosynthesis II (Oryza sativa)

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1111111cytosolH+H2OH+H2O6-deoxoteasteronecampesterolH2OO2H2OO2H+6-deoxocathasteroneH+H+NADPHcampestanolNADPH(22alpha)-hydroxy-campest-4-en-3-one3-oxo-5-alpha-steroid4-dehydrogenase(LOC_OS01G63260.1)NADPHNADPH(22alpha)-hydroxy-campesterolNADPHNADP+NADPH(22alpha)-hydroxy-5alpha-campestan-3-onecampesterol22alpha-hydroxylaseNADP+campest-4-en-3-oneO2NADP+O2campesterol22alpha-hydroxylasecampesterol22alpha-hydroxylase3-oxo-5-alpha-steroid4-dehydrogenaseNADP+(5alpha)-campestan-3-oneNADP+O2campesterol22alpha-hydroxylasecampest-4-en-3beta-olH+6-deoxocathasteronehydroxylaseNADP+H2O


Description

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Quality Tags

Ontology Terms

 

Bibliography

  1. Zhao B, Li J.; ''Regulation of brassinosteroid biosynthesis and inactivation.''; PubMed Europe PMC Scholia

History

CompareRevisionActionTimeUserComment
118533view10:55, 28 May 2021EweitzOntology Term : 'brassinosteroid biosynthetic pathway' added !
118239view12:03, 26 May 2021EweitzModified title
82024view14:40, 8 September 2015Anweshafixing title, data source, & tagging incomplete pathways
80477view14:47, 25 June 2015AnweshaNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
(22alpha)-hydroxy-5alpha-campestan-3-oneMetaboliteCHEBI:59411 (ChEBI)
(22alpha)-hydroxy-campest-4-en-3-oneMetaboliteCHEBI:72330 (ChEBI)
(22alpha)-hydroxy-campesterolMetaboliteCHEBI:72331 (ChEBI)
(5alpha)-campestan-3-oneMetaboliteCHEBI:18533 (ChEBI)
3-oxo-5-alpha-steroid

4-dehydrogenase

(LOC_OS01G63260.1)		ProteinQ8LQ34 (Uniprot-TrEMBL) Catalyzes the conversion of (22alpha)-hydroxy-campest-4-en-3-one into (22alpha)-hydroxy-5alpha-campestan-3-one.
3-oxo-5-alpha-steroid 4-dehydrogenaseProtein1121931 (Reactome) Catalyzes the conversion of (22alpha)-hydroxy-campest-4-en-3-one into (22alpha)-hydroxy-5alpha-campestan-3-one.
6-deoxocathasterone hydroxylaseProtein2730792 (Reactome) Catalyzes the conversion of 6-deoxocathasterone into 6-deoxoteasterone.
6-deoxocathasteroneMetaboliteCHEBI:20714 (ChEBI)
6-deoxoteasteroneMetaboliteCHEBI:20716 (ChEBI)
H+MetaboliteCHEBI:15378 (ChEBI)
H2OMetaboliteCHEBI:15377 (ChEBI)
NADP+MetaboliteCHEBI:18009 (ChEBI)
NADPHMetaboliteCHEBI:16474 (ChEBI)
O2MetaboliteCHEBI:15379 (ChEBI)
campest-4-en-3-oneMetaboliteCHEBI:18534 (ChEBI)
campest-4-en-3beta-olMetaboliteCHEBI:18535 (ChEBI)
campestanolMetaboliteCHEBI:36799 (ChEBI)
campesterol 22alpha-hydroxylaseProtein2730789 (Reactome) Catalyzes the conversion of campestanol into 6-deoxocathasterone.
campesterolMetaboliteCHEBI:28623 (ChEBI)

Annotated Interactions

View all...
SourceTargetTypeDatabase referenceComment
(22alpha)-hydroxy-5alpha-campestan-3-one1119653 (Reactome)
(22alpha)-hydroxy-5alpha-campestan-3-oneArrow1120406 (Reactome)
(22alpha)-hydroxy-5alpha-campestan-3-oneArrow1120463 (Reactome)
(22alpha)-hydroxy-campest-4-en-3-one1120406 (Reactome)
(22alpha)-hydroxy-campest-4-en-3-oneArrow1121099 (Reactome)
(22alpha)-hydroxy-campest-4-en-3-oneArrow1121417 (Reactome)
(22alpha)-hydroxy-campesterol1121417 (Reactome)
(22alpha)-hydroxy-campesterolArrow1121265 (Reactome)
(5alpha)-campestan-3-one1119679 (Reactome)
(5alpha)-campestan-3-one1120463 (Reactome)
(5alpha)-campestan-3-oneArrow1121695 (Reactome)
1119653 (Reactome)
1119679 (Reactome)
1119715 (Reactome) Campesterol is converted into campest-4-en-3beta-ol by enzymatic activity of an unknown gene product.
1119894 (Reactome) 6-deoxocathasterone is converted into 6-deoxoteasterone by enzymatic activity of 6-deoxoocathasterone hydroxylase.
1119942 (Reactome)
1120406 (Reactome) (22alpha)-hydroxy-campest-4-en-3-one is converted into (22alpha)hydroxy-5alpha-campestan-3-one by enzymatic activity of 3-oxo-5-alpha-steroid 4-dehydrogenase.
1120463 (Reactome) (5alpha)-campestan-3-one is converted into (22alpha)-hydroxy-5alpha-campestan-3-one by enzymatic activity of campesterol 22alpha-hydroxylase.
1121099 (Reactome) Campest-4-en-3-one is converted into (22alpha)-hydroxy-campest-4-en-3-one by enzymatic activity of campesterol 22alpha-hydroxylase.
1121265 (Reactome) Campesterol is converted into (22alpha)-hydroxy-campesterol by enzymatic activity of campesterol 22alpha-hydroxylase.
1121417 (Reactome)
1121576 (Reactome) Campestanol is converted into 6-deoxocathasterone by enzymatic activity of campesterol 22alpha-hydroxylase.
1121695 (Reactome) Campest-4-en-3-one is converted into (5alpha)-campestan-3-one by enzymatic activity of 3-oxo-5-alpha-steroid 4-dehydrogenase.
3-oxo-5-alpha-steroid

4-dehydrogenase

(LOC_OS01G63260.1)		mim-catalysis1121695 (Reactome)
3-oxo-5-alpha-steroid 4-dehydrogenasemim-catalysis1120406 (Reactome)
6-deoxocathasterone hydroxylasemim-catalysis1119894 (Reactome)
6-deoxocathasterone1119894 (Reactome)
6-deoxocathasteroneArrow1119653 (Reactome)
6-deoxocathasteroneArrow1121576 (Reactome)
6-deoxoteasteroneArrow1119894 (Reactome)
H+1120406 (Reactome)
H+1120463 (Reactome)
H+1121099 (Reactome)
H+1121265 (Reactome)
H+1121576 (Reactome)
H+1121695 (Reactome)
H2OArrow1119894 (Reactome)
H2OArrow1120463 (Reactome)
H2OArrow1121099 (Reactome)
H2OArrow1121265 (Reactome)
H2OArrow1121576 (Reactome)
NADP+Arrow1120406 (Reactome)
NADP+Arrow1120463 (Reactome)
NADP+Arrow1121099 (Reactome)
NADP+Arrow1121265 (Reactome)
NADP+Arrow1121576 (Reactome)
NADP+Arrow1121695 (Reactome)
NADPH1120406 (Reactome)
NADPH1120463 (Reactome)
NADPH1121099 (Reactome)
NADPH1121265 (Reactome)
NADPH1121576 (Reactome)
NADPH1121695 (Reactome)
O21119894 (Reactome)
O21120463 (Reactome)
O21121099 (Reactome)
O21121265 (Reactome)
O21121576 (Reactome)
campest-4-en-3-one1121099 (Reactome)
campest-4-en-3-one1121695 (Reactome)
campest-4-en-3-oneArrow1119942 (Reactome)
campest-4-en-3beta-ol1119942 (Reactome)
campest-4-en-3beta-olArrow1119715 (Reactome)
campestanol1121576 (Reactome)
campestanolArrow1119679 (Reactome)
campesterol 22alpha-hydroxylasemim-catalysis1120463 (Reactome)
campesterol 22alpha-hydroxylasemim-catalysis1121099 (Reactome)
campesterol 22alpha-hydroxylasemim-catalysis1121265 (Reactome)
campesterol 22alpha-hydroxylasemim-catalysis1121576 (Reactome)
campesterol1119715 (Reactome)
campesterol1121265 (Reactome)
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP2962"
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