Overview of nanoparticle effects (Homo sapiens)
From WikiPathways
Description
No description
Quality Tags
Ontology Terms
Bibliography
View all... |
- Zolnik BS, Gonzalez-Fernandez A, Sadrieh N, Dobrovolskaia MA; ''Nanoparticles and the immune system.''; Endocrinology, 2010 PubMed Europe PMC Scholia
- Chen T, Hu J, Chen C, Pu J, Cui X, Jia G; ''Cardiovascular effects of pulmonary exposure to titanium dioxide nanoparticles in ApoE knockout mice.''; J Nanosci Nanotechnol, 2013 PubMed Europe PMC Scholia
- Li JG, Li WX, Xu JY, Cai XQ, Liu RL, Li YJ, Zhao QF, Li QN; ''Comparative study of pathological lesions induced by multiwalled carbon nanotubes in lungs of mice by intratracheal instillation and inhalation.''; Environ Toxicol, 2007 PubMed Europe PMC Scholia
- Triboulet S, Aude-Garcia C, Carriere M, Diemer H, Proamer F, Habert A, Chevallet M, Collin-Faure V, Strub JM, Hanau D, Van Dorsselaer A, Herlin-Boime N, Rabilloud T; ''Molecular responses of mouse macrophages to copper and copper oxide nanoparticles inferred from proteomic analyses.''; Mol Cell Proteomics, 2013 PubMed Europe PMC Scholia
- Nel A, Xia T, Maedler L, Li N; ''Toxic potential of materials at the nanolevel.''; Science, 2006 PubMed Europe PMC Scholia
- Ilinskaya AN, Dobrovolskaia MA; ''Immunosuppressive and anti-inflammatory properties of engineered nanomaterials.''; Br J Pharmacol, 2014 PubMed Europe PMC Scholia
- Hohnholt MC, Geppert M, Luther EM, Petters C, Bulcke F, Dringen R; ''Handling of iron oxide and silver nanoparticles by astrocytes.''; Neurochem Res, 2013 PubMed Europe PMC Scholia
- Nawrot TS, Perez L, Kuenzli N, Munters E, Nemery B; ''Public health importance of triggers of myocardial infarction: a comparative risk assessment.''; Lancet, 2011 PubMed Europe PMC Scholia
- Johnson-Lyles DN, Peifley K, Lockett S, Neun BW, Hansen M, Clogston J, Stern ST, McNeil SE; ''Fullerenol cytotoxicity in kidney cells is associated with cytoskeleton disruption, autophagic vacuole accumulation, and mitochondrial dysfunction.''; Toxicol Appl Pharmacol, 2010 PubMed Europe PMC Scholia
- Ma YH, Huang CP, Tsai JS, Shen MY, Li YK, Lin LY; ''Water-soluble germanium nanoparticles cause necrotic cell death and the damage can be attenuated by blocking the transduction of necrotic signaling pathway.''; Toxicol Lett, 2011 PubMed Europe PMC Scholia
- Rauch J, Kolch W, Laurent S, Mahmoudi M; ''Big signals from small particles: regulation of cell signaling pathways by nanoparticles.''; Chem Rev, 2013 PubMed Europe PMC Scholia
- Andon FT, Fadeel B; ''Programmed cell death: molecular mechanisms and implications for safety assessment of nanomaterials.''; Acc Chem Res, 2013 PubMed Europe PMC Scholia
- Ma L, Zhao J, Wang J, Liu J, Duan Y, Liu H, Li N, Yan J, Ruan J, Wang H, Hong F; ''The Acute Liver Injury in Mice Caused by Nano-Anatase TiO2.''; Nanoscale Res Lett, 2009 PubMed Europe PMC Scholia
- Greish K, Thiagarajan G, Herd H, Price R, Bauer H, Hubbard D, Burckle A, Sadekar S, Yu T, Anwar A, Ray A, Ghandehari H; ''Size and surface charge significantly influence the toxicity of silica and dendritic nanoparticles.''; Nanotoxicology, 2012 PubMed Europe PMC Scholia
- Du Z, Zhao D, Jing L, Cui G, Jin M, Li Y, Liu X, Liu Y, Du H, Guo C, Zhou X, Sun Z; ''Cardiovascular toxicity of different sizes amorphous silica nanoparticles in rats after intratracheal instillation.''; Cardiovasc Toxicol, 2013 PubMed Europe PMC Scholia
- Tian F, Cui D, Schwarz H, Estrada GG, Kobayashi H; ''Cytotoxicity of single-wall carbon nanotubes on human fibroblasts.''; Toxicol In Vitro, 2006 PubMed Europe PMC Scholia
- Azim SA, Darwish HA, Rizk MZ, Ali SA, Kadry MO; ''Amelioration of titanium dioxide nanoparticles-induced liver injury in mice: possible role of some antioxidants.''; Exp Toxicol Pathol, 2015 PubMed Europe PMC Scholia
- Nemmar A, Holme JA, Rosas I, Schwarze PE, Alfaro-Moreno E; ''Recent advances in particulate matter and nanoparticle toxicology: a review of the in vivo and in vitro studies.''; Biomed Res Int, 2013 PubMed Europe PMC Scholia
History
View all... |
External references
DataNodes
View all... |
Name | Type | Database reference | Comment |
---|---|---|---|
AKT | GeneProduct | ENSG00000117020 (Ensembl) | |
Actin | GeneProduct | ||
Acute lung effects: hypercoagulation, hypofibrinolysis, etc. | |||
Angiogenesis | Pathway | WP1539 (WikiPathways) | |
Apoptosis | Pathway | WP2507 (WikiPathways) | |
Autophagic cell death | Pathway | WP2509 (WikiPathways) | |
Bax | GeneProduct | ENSG00000087088 (Ensembl) | |
Bcl-2 | GeneProduct | ENSG00000171791 (Ensembl) | |
Blood coagulation | Pathway | WP558 (WikiPathways) | |
C-reactive protein | GeneProduct | ENSG00000132693 (Ensembl) | |
COX1 (PTGS1) | GeneProduct | ENSG00000095303 (Ensembl) | |
COX2 (PTGS2) | GeneProduct | ENSG00000073756 (Ensembl) | |
Cell adhesion | Pathway | WP306 (WikiPathways) | |
Cell cycle | Pathway | WP179 (WikiPathways) | |
Cell death | |||
Coronary heart disease, plaques, DIC | |||
Cytoskeleton | Pathway | WP51 (WikiPathways) | |
DNA damage | |||
DNA damage response | Pathway | WP707 (WikiPathways) | |
Differentiation | Pathway | ||
Endocytosis
Exocytosis Phagocytosis | Pathway | ||
FAK (PTK2) | GeneProduct | ENSG00000169398 (Ensembl) | |
Genotoxicity / Cancer | |||
Glutathione | Metabolite | 16856 (ChEBI) | |
HMOX1 | GeneProduct | ENSG00000100292 (Ensembl) | |
IL-6 | GeneProduct | ENSG00000136244 (Ensembl) | |
Il-6 signaling | Pathway | WP364 (WikiPathways) | |
Il-8 | GeneProduct | ENSG00000169429 (Ensembl) | |
Immune system up or down regulation | Pathway | WP2783 (WikiPathways) | |
Inflammation | Pathway | WP453 (WikiPathways) | |
Integrin | GeneProduct | ||
Metallothionein | GeneProduct | ||
Migration | Pathway | ||
Mitochondria potential | |||
NF-kB | GeneProduct | ENSG00000170322 (Ensembl) | |
Nanoparticle | |||
Necrosis | Pathway | WP2513 (WikiPathways) | |
Necrotopsis | Pathway | WP2513 (WikiPathways) | |
Oxidative stress | Pathway | WP408 (WikiPathways) | |
P-cadherin | GeneProduct | ENSG00000062038 (Ensembl) | |
PI3K | GeneProduct | ENSG00000171608 (Ensembl) | |
Prostaglandin | Metabolite | ||
Prostaglandin pathway | Pathway | WP98 (WikiPathways) | |
TNF-a Signaling | Pathway | WP231 (WikiPathways) | |
TNF-a | GeneProduct | ENSG00000232810 (Ensembl) | |
collagen IV | GeneProduct | ||
cyclin D3 | GeneProduct | ENSG00000112576 (Ensembl) | |
ferritin | GeneProduct | ||
fibronectin | GeneProduct | ||
laminin | GeneProduct |
Annotated Interactions
No annotated interactions