Hypothetical craniofacial development pathway (Homo sapiens)

From WikiPathways

Description

Quality Tags

Ontology Terms

Bibliography

1. Leslie EJ, Mansilla MA, Biggs LC, Schuette K, Bullard S, Cooper M, Dunnwald M, Lidral AC, Marazita ML, Beaty TH, Murray JC; ''Expression and mutation analyses implicate ARHGAP29 as the etiologic gene for the cleft lip with or without cleft palate locus identified by genome-wide association on chromosome 1p22.''; Birth Defects Res A Clin Mol Teratol, 2012 PubMed Europe PMC Scholia

History

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Compare	Revision	Action	Time	User	Comment
	129299	view	22:56, 25 March 2024	Khanspers	updated Wnt node, updated xrefs, improved layout
	117757	view	12:52, 22 May 2021	Eweitz	Modified title
	106749	view	13:23, 17 September 2019	MaintBot	HMDB identifier normalization
	88473	view	23:28, 9 August 2016	AAR&Co	Ontology Term : 'cleft lip' added !
	88472	view	23:28, 9 August 2016	AAR&Co	Ontology Term : 'signaling pathway' added !
	88471	view	23:27, 9 August 2016	AAR&Co	Ontology Term : 'signaling pathway pertinent to development' added !
	88470	view	23:26, 9 August 2016	AAR&Co	Edited Interactions and Labels
	85922	view	18:12, 21 June 2016	AAR&Co	Modified description
	85785	view	13:26, 13 June 2016	AAR&Co	Modified description
	85784	view	13:16, 13 June 2016	AAR&Co	Added Literature Citation
	85783	view	13:06, 13 June 2016	AAR&Co	New pathway

External references

DataNodes

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Name	Type	Database reference	Comment
ARHGAP29	GeneProduct	ENSG00000137962 (Ensembl)
GDP	Metabolite	HMDB00960 (HMDB)
GEF	GeneProduct	ENSG00000275340 (Ensembl)
GTP	Metabolite	HMDB01440 (HMDB)
IRF6	GeneProduct	ENSG00000117595 (Ensembl)
RHOA	GeneProduct	ENSG00000067560 (Ensembl)
RhoA	GeneProduct	ENSG00000067560 (Ensembl)
TFAP2A	GeneProduct	ENSG00000137203 (Ensembl)
TGFB3	GeneProduct	ENSG00000119699 (Ensembl)
TP63	GeneProduct	ENSG00000073282 (Ensembl)
WNT	GeneProduct	ENSG00000125084 (Ensembl)	WNT Not Specified

Annotated Interactions

No annotated interactions