lncRNA-mediated mechanisms of therapeutic resistance (Homo sapiens)

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1Drug-resistantcancer cellsChemotherapyHCC cellsTransporterexpressionImpaired drug expulsionCell survivalTP53UCA1ApoptosisCell proliferationG0/G1 cell cycle arrestHOTAIRWNT6linc-RoRHIF1Ap21MEG3AK126698MRULlinc-VLDLRP-gpBcl-xlHypoxiaRecipient cellsEVsEV linc-RoREV linc-VLDLR


Description

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Bibliography

  1. Parasramka MA, Maji S, Matsuda A, Yan IK, Patel T; ''Long non-coding RNAs as novel targets for therapy in hepatocellular carcinoma.''; Pharmacol Ther, 2016 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
123394view06:24, 23 July 2022EgonwMade a pathway clickable
117771view13:56, 22 May 2021EweitzModified title
108191view10:55, 29 November 2019FehrhartOntology Term : 'cancer pathway' added !
106632view20:56, 12 September 2019KhanspersModified description
105511view06:02, 8 August 2019KhanspersModified description
96967view01:39, 24 April 2018AlexanderPicocondensed layout
87395view11:05, 22 July 2016MaintBotadded missing graphids
86056view23:01, 28 June 2016KhanspersModified description
86053view21:46, 28 June 2016KhanspersOntology Term : 'antineoplastic drug pathway' added !
86052view21:44, 28 June 2016KhanspersOntology Term : 'long non-coding RNA pathway' added !
86051view21:43, 28 June 2016KhanspersOntology Term : 'hepatocellular carcinoma' added !
86050view21:41, 28 June 2016Khanspersupdated data node color and type
86049view21:40, 28 June 2016KhanspersModified description
86048view21:39, 28 June 2016KhanspersNew pathway

External references

DataNodes

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NameTypeDatabase referenceComment
AK126698GeneProductENSG00000203601 (Ensembl)
ApoptosisPathwayWP254 (WikiPathways)
Bcl-xlGeneProductENSG00000171552 (Ensembl)
Cell proliferationPathway
EV linc-RoRRnaENSG00000258609 (Ensembl)
EV linc-VLDLRRna401491 (Entrez Gene)
G0/G1 cell cycle arrestPathway
HIF1AGeneProductENSG00000100644 (Ensembl)
HOTAIRRnaENSG00000228630 (Ensembl)
MEG3RnaENSG00000214548 (Ensembl)
MRULRna
P-gpGeneProductENSG00000085563 (Ensembl)
TP53GeneProductENSG00000141510 (Ensembl)
UCA1RnaENSG00000214049 (Ensembl)
WNT6GeneProductENSG00000115596 (Ensembl)
linc-RoRRnaENSG00000258609 (Ensembl)
linc-VLDLRRna401491 (Entrez Gene)
p21GeneProductENSG00000124762 (Ensembl)

Annotated Interactions

No annotated interactions

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