IL-4 signaling pathway (Gallus gallus)

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DDDeacetylationCY -> PMDephosphorylationActivationProteolytic cleavageTranslocationEndosomeExtracellularUbiquitinationEndoplasmic reticulum(Protein-protein interaction)DCY -> NULigandPhosphorylationENAutophosphorylationERMolecular associationAccession Number: NetPath 16DCY -> NUCYGOReaction through unknown mechanisms/moleculesDemethylationMitochondrionReceptorPMDCytoplasmDPalmitoylationControlGlycosylationDeubiquitinationSumoylationAcetylationMTEnzyme complexNucleusDInhibitionRecruitmentCY -> PMCY -> PMGolgi apparatusPlasma membraneECProteins in a complex interactionDMethylationCY -> PMDMolecule in the pathwayNUDesumoylationPRKD3PIK3R1NFKB1STAT6PIK3CDPIK3R2CREBBPJAK2ADRBK2RCJMB04_16p24BCL2L1SPI1JAK1NFKB1RCJMB04_4j14JAK3RCJMB04_16p24RASA1IL4RCJMB04_17i9STAT6PRKCZSOS1Gene SymbolPRKCDELK1HIST2H3CPRKCZIL13RA1LCKGRB2MAPK3SOCS3MAPK14INPP5DIL4RPIK3CAPRKD3PTK2RELAIL4RATF2FYNIL4ETS1MAPK11SOCS5JAK2IL2RGHMGA1STAT5AAKT1EP300PLCG1CBLSTAT6MAPK1FESMAPK14PTPN6STAT6TYK2JAK1PTPN11IRS2PRKCDNCF1CXCR4DOK2PAWRSTAMSRCIRS1SHC1STAT6SOCS1BAD


Description

No description

Comments

GenMAPP notes 
NetPath 16 - IL-4 Signaling Pathway

NetPath (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the NetPath website until the pathway is published.

GenMAPP remarks 
http://www.netpath.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP395(r28126) with a 68% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
117989view11:23, 23 May 2021EweitzModified title
86931view13:05, 15 July 2016MkutmonOntology Term : 'interleukin-4 signaling pathway' added !
68846view17:19, 8 July 2013MaintBotUpdated to 2013 gpml schema
40984view22:55, 1 March 2011MaintBotRemoved redundant pathway information and comments
33908view18:02, 9 December 2009MaintBotAutomatic update of empty xrefs
31538view21:47, 13 August 2009MaintBotFixed text labels
30387view21:04, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
ADRBK2GeneProduct416904 (Entrez Gene)
AKT1GeneProduct395928 (Entrez Gene)
ATF2GeneProduct395727 (Entrez Gene)
BADGeneProduct
BCL2L1GeneProduct373954 (Entrez Gene)
CBLGeneProduct374038 (Entrez Gene)
CREBBPGeneProduct416667 (Entrez Gene)
CXCR4GeneProduct395324 (Entrez Gene)
DOK2GeneProduct
ELK1GeneProduct
EP300GeneProduct418000 (Entrez Gene)
ETS1GeneProduct768354 (Entrez Gene)
FESGeneProduct429374 (Entrez Gene)
FYNGeneProduct396294 (Entrez Gene)
GRB2GeneProduct386572 (Entrez Gene)
Gene SymbolGeneProduct
HIST2H3CGeneProduct
HMGA1GeneProduct378795 (Entrez Gene)
IL13RA1GeneProduct422230 (Entrez Gene)
IL2RGGeneProduct395199 (Entrez Gene)
IL4GeneProduct416330 (Entrez Gene)
IL4RGeneProduct416585 (Entrez Gene)
INPP5DGeneProduct424745 (Entrez Gene)
IRS1GeneProduct429126 (Entrez Gene)
IRS2GeneProduct428017 (Entrez Gene)
JAK1GeneProduct395681 (Entrez Gene)
JAK2GeneProduct374199 (Entrez Gene)
JAK3GeneProduct395845 (Entrez Gene)
LCKGeneProduct
MAPK11GeneProduct417739 (Entrez Gene)
MAPK1GeneProduct373953 (Entrez Gene)
MAPK14GeneProduct421183 (Entrez Gene)
MAPK3GeneProduct
NCF1GeneProduct
NFKB1GeneProduct396033 (Entrez Gene)
PAWRGeneProduct417870 (Entrez Gene)
PIK3CAGeneProduct424971 (Entrez Gene)
PIK3CDGeneProduct419444 (Entrez Gene)
PIK3R1GeneProduct427171 (Entrez Gene)
PIK3R2GeneProduct771142 (Entrez Gene)
PLCG1GeneProduct
PRKCDGeneProduct415905 (Entrez Gene)
PRKCZGeneProduct419399 (Entrez Gene)
PRKD3GeneProduct421478 (Entrez Gene)
PTK2GeneProduct396416 (Entrez Gene)
PTPN11GeneProduct395815 (Entrez Gene)
PTPN6GeneProduct427947 (Entrez Gene)
RASA1GeneProduct427327 (Entrez Gene)
RCJMB04_16p24GeneProduct424991 (Entrez Gene)
RCJMB04_17i9GeneProduct424044 (Entrez Gene)
RCJMB04_4j14GeneProduct417637 (Entrez Gene)
RELAGeneProduct
SHC1GeneProduct395934 (Entrez Gene)
SOCS1GeneProduct416630 (Entrez Gene)
SOCS3GeneProduct395299 (Entrez Gene)
SOCS5GeneProduct428570 (Entrez Gene)
SOS1GeneProduct425964 (Entrez Gene)
SPI1GeneProduct395879 (Entrez Gene)
SRCGeneProduct396442 (Entrez Gene)
STAMGeneProduct420517 (Entrez Gene)
STAT5AGeneProduct
STAT6GeneProduct
TYK2GeneProduct395741 (Entrez Gene)

Annotated Interactions

No annotated interactions
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