IL-5 signaling pathway (Pan troglodytes)

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UbiquitinationCY->PMPalmitoylationENDemethylationMolecular associationDDReaction through unknown mechanisms/moleculesCYDEndoplasmic reticulumCY->MTDDDeacetylationERDInhibitionPM->NUGolgi apparatusECDCY->NUTranslocationDPM->NUCY->NUNucleusDesumoylationExtracellularEnzyme complexSumoylationProteins in a complex interactionRecruitmentMethylationPMActivationPM->NUMolecule in the pathwayAutophosphorylationDephosphorylationReceptorLigandDDDDDPhosphorylationDDDGene Symbol(Protein-protein interaction)Plasma membraneNUCY->NUControlProteolytic cleavageMitochondriaGlycosylationCytoplasmDeubiquitinationGOEndosomeDAccession Number: NetPath 17AcetylationMTDCTNNB1NFKBIARAPGEF1AKT1JAK1IL2RBPTK2BSYKITGAMLYNCTNNB1STAT5AALOX5APPTPN11JUNCRKLPTPN6CCND3SH2B2DNM2BAXRPS6KA1STAT3PIK3CGMAPK9PIM1CSF2RBPRKCDKRASCDKN1BMAPK1RAC1NFKB1VAV1BAXHCLS1IL5RAIL5ELK1RAP1GAPUNC119BTKPRKCB1YWHAZICAM1ALOX5SOCS1NFKB1MAPK3ALOX5FOXO3AIL5RASDCBPRAF1HCKITGB2PLA2G4ASTAT5AIL5SOX4STAT5BCSF2RBMAP2K2SHC2MAPK14SHC1PIK3R2HRASATF2GRB2CBLPIK3R1STAT1ICAM3PRKCDCSF2RBCRKLGSK3ASTAT5BGSK3BJAK2


Description

No description

Comments

GenMAPP notes 
NetPath 17 - IL-5 Signaling Pathway

NetPath (http://www.netpath.org) is a collaborative project between PandeyLab at Johns Hopkins University (http://pandeylab.igm.jhmi.edu) and the Institute of Bioinformatics (http://www.ibioinformatics.org). If you use this pathway, you must cite the NetPath website until the pathway is published.

GenMAPP remarks 
http://www.netpath.org
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP127(r20949) with a 83% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

View all...
CompareRevisionActionTimeUserComment
117997view11:24, 23 May 2021EweitzModified title
86936view13:07, 15 July 2016MkutmonOntology Term : 'interleukin-5 signaling pathway' added !
69246view18:35, 8 July 2013MaintBotUpdated to 2013 gpml schema
41551view01:58, 2 March 2011MaintBotRemoved redundant pathway information and comments
34282view21:58, 9 December 2009MaintBotAutomatic update of empty xrefs
31558view21:54, 13 August 2009MaintBotFixed text labels
30418view21:15, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
AKT1GeneProduct740898 (Entrez Gene)
ALOX5GeneProduct450428 (Entrez Gene)
ALOX5APGeneProduct452520 (Entrez Gene)
ATF2GeneProduct
BAXGeneProduct747093 (Entrez Gene)
BTKGeneProduct465759 (Entrez Gene)
CBLGeneProduct451690 (Entrez Gene)
CCND3GeneProduct462689 (Entrez Gene)
CDKN1BGeneProduct466947 (Entrez Gene)
CRKLGeneProduct470146 (Entrez Gene)
CSF2RBGeneProduct458802 (Entrez Gene)
CTNNB1GeneProduct450183 (Entrez Gene)
DNM2GeneProduct455718 (Entrez Gene)
ELK1GeneProduct
FOXO3AGeneProduct
GRB2GeneProduct737245 (Entrez Gene)
GSK3AGeneProduct456071 (Entrez Gene)
GSK3BGeneProduct470896 (Entrez Gene)
HCKGeneProduct458163 (Entrez Gene)
HCLS1GeneProduct460623 (Entrez Gene)
HRASGeneProduct466302 (Entrez Gene)
ICAM1GeneProduct450196 (Entrez Gene)
ICAM3GeneProduct494138 (Entrez Gene)
IL2RBGeneProduct470203 (Entrez Gene)
IL5GeneProduct743963 (Entrez Gene)
IL5RAGeneProduct737582 (Entrez Gene)
ITGAMGeneProduct454069 (Entrez Gene)
ITGB2GeneProduct458607 (Entrez Gene)
JAK1GeneProduct743373 (Entrez Gene)
JAK2GeneProduct464979 (Entrez Gene)
JUNGeneProduct456893 (Entrez Gene)
KRASGeneProduct473387 (Entrez Gene)
LYNGeneProduct472771 (Entrez Gene)
MAP2K2GeneProduct456390 (Entrez Gene)
MAPK14GeneProduct450161 (Entrez Gene)
MAPK1GeneProduct458680 (Entrez Gene)
MAPK3GeneProduct454037 (Entrez Gene)
MAPK9GeneProduct462336 (Entrez Gene)
NFKB1GeneProduct461406 (Entrez Gene)
NFKBIAGeneProduct467426 (Entrez Gene)
PIK3CGGeneProduct463649 (Entrez Gene)
PIK3R1GeneProduct461836 (Entrez Gene)
PIK3R2GeneProduct455855 (Entrez Gene)
PIM1GeneProduct462656 (Entrez Gene)
PLA2G4AGeneProduct469617 (Entrez Gene)
PRKCB1GeneProduct
PRKCDGeneProduct
PTK2BGeneProduct464073 (Entrez Gene)
PTPN11GeneProduct748225 (Entrez Gene)
PTPN6GeneProduct748032 (Entrez Gene)
RAC1GeneProduct
RAF1GeneProduct460182 (Entrez Gene)
RAP1GAPGeneProduct
RAPGEF1GeneProduct464812 (Entrez Gene)
RPS6KA1GeneProduct
SDCBPGeneProduct464192 (Entrez Gene)
SH2B2GeneProduct741557 (Entrez Gene)
SHC1GeneProduct457351 (Entrez Gene)
SHC2GeneProduct
SOCS1GeneProduct737070 (Entrez Gene)
SOX4GeneProduct471866 (Entrez Gene)
STAT1GeneProduct459834 (Entrez Gene)
STAT3GeneProduct454682 (Entrez Gene)
STAT5AGeneProduct454681 (Entrez Gene)
STAT5BGeneProduct454679 (Entrez Gene)
SYKGeneProduct464586 (Entrez Gene)
UNC119GeneProduct455028 (Entrez Gene)
VAV1GeneProduct455647 (Entrez Gene)
YWHAZGeneProduct472830 (Entrez Gene)

Annotated Interactions

No annotated interactions
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