Dysregulated miRNA targeting in insulin/PI3K-AKT signaling (Mus musculus)

From WikiPathways

Description

Quality Tags

Ontology Terms

Bibliography

1. Kwon DN, Chang BS, Kim JH; ''MicroRNA dysregulation in liver and pancreas of CMP-Neu5Ac hydroxylase null mice disrupts insulin/PI3K-AKT signaling.''; Biomed Res Int, 2014 PubMed Europe PMC Scholia

History

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Compare	Revision	Action	Time	User	Comment
	128795	view	01:43, 22 February 2024	Eweitz	Standardize case
	123115	view	07:06, 4 July 2022	Egonw	Made two pathways clickable
	116445	view	09:51, 7 May 2021	Eweitz	Modified title
	89747	view	23:54, 29 September 2016	Khanspers	Modified title
	89746	view	23:53, 29 September 2016	Khanspers	Modified title
	89644	view	23:42, 22 September 2016	Khanspers	corrected direction of miRNA-target interactions
	88610	view	23:00, 11 August 2016	AAR&Co	Added Data Node
	88609	view	22:58, 11 August 2016	AAR&Co	Added DataNode
	87414	view	11:31, 22 July 2016	Mkutmon	Ontology Term : 'regulatory pathway' added !
	87257	view	14:22, 20 July 2016	AAR&Co	Ontology Term : 'type 2 diabetes mellitus' added !
	87256	view	14:22, 20 July 2016	AAR&Co	Ontology Term : 'glucose intolerance' added !
	87255	view	14:21, 20 July 2016	AAR&Co	Modified description
	87254	view	14:09, 20 July 2016	AAR&Co	Added Citation
	87253	view	13:51, 20 July 2016	AAR&Co	New pathway

External references

DataNodes

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Name	Type	Database reference	Comment
Acaca	GeneProduct	ENSMUSG00000020532 (Ensembl)
Bad	GeneProduct	ENSMUSG00000024959 (Ensembl)
Bcl2	GeneProduct	ENSMUSG00000057329 (Ensembl)
Bcl2l11	GeneProduct	ENSMUSG00000027381 (Ensembl)
Ccnd2	GeneProduct	ENSMUSG00000000184 (Ensembl)
Cdkn1b	GeneProduct	ENSMUSG00000003031 (Ensembl)
Col1a1	GeneProduct	ENSMUSG00000001506 (Ensembl)
Col1a2	GeneProduct	ENSMUSG00000029661 (Ensembl)
Col3a1	GeneProduct	ENSMUSG00000026043 (Ensembl)
Col4a2	GeneProduct	ENSMUSG00000031503 (Ensembl)
Col5a3	GeneProduct	ENSMUSG00000004098 (Ensembl)
Crkl	GeneProduct	ENSMUSG00000006134 (Ensembl)
Eif4e2	GeneProduct	ENSMUSG00000026254 (Ensembl)
Exoc7	GeneProduct	ENSMUSG00000020792 (Ensembl)
Fasn	GeneProduct	ENSMUSG00000025153 (Ensembl)
Flot2	GeneProduct	ENSMUSG00000061981 (Ensembl)
Insulin Signaling	Pathway	Insulin Signaling (Mus musculus) (WikiPathways)
Mapk3	GeneProduct	ENSMUSG00000063065 (Ensembl)
Mtor	GeneProduct	ENSMUSG00000028991 (Ensembl)
PI3K/AKT Signalling	Pathway	N/A (WikiPathways)
Pik3r1	GeneProduct	ENSMUSG00000041417 (Ensembl)
Pik3r3	GeneProduct	ENSMUSG00000028698 (Ensembl)
Prkar2a	GeneProduct	ENSMUSG00000032601 (Ensembl)
Prkx	GeneProduct	ENSMUSG00000035725 (Ensembl)
Raf1	GeneProduct	ENSMUSG00000000441 (Ensembl)
Rheb	GeneProduct	ENSMUSG00000028945 (Ensembl)
Socs1	GeneProduct	ENSMUSG00000038037 (Ensembl)
Sos1	GeneProduct	ENSMUSG00000024241 (Ensembl)
mmu-miR-155-5p	Rna	MI0000177 (miRBase Sequence)
mmu-miR-15a-5p	Rna	MIMAT0000526 (miRBase Sequence)
mmu-miR-16-5p	Rna	MIMAT0000527 (miRBase Sequence)
mmu-miR-29a-3p	Rna	MIMAT0000535 (miRBase Sequence)
mmu-miR-29b-3p	Rna	MIMAT0000127 (miRBase Sequence)
mmu-miR-425-5p	Rna	MIMAT0004750 (miRBase Sequence)
mmu-miR-503-5p	Rna	MIMAT0003188 (miRBase Sequence)

Annotated Interactions

No annotated interactions