Novel intracellular components of RIG-I-like receptor pathway (Homo sapiens)

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Type I inteferonApoptosisCYLDCXCL8Ub-mediated proteolysisDDX3YTMEM173MAPK11MAPK14short dsRNAMAPK12MAPK13DDX17MAPK8DDX58ISG15TRIM25ATG5ATG12NLRX1MAVSDHX58RNF125IFIH1DAKOTUD5TRAF3TRADDTANKAZI2TBKBP1FADDRIPK1SIKE1IKBKETBK1IKBKGCASP8CASP10DDX3XPIN1IRF3IRF7IKBKGCHUKIKBKBNFKBIANFKBIBNFKB1RELAMAPK10MAPK9MAP3K7MAP3K1TRAF2TRAF6IRF3IRF7NFKB1RELAIFNGIFNA1IFNB1IFNEIFNKTNFACXCL12CXCL10Inflammatory cytokinesNucleus5'ppp-RNAlong dsRNAViral pathogensUb-mediated proteolysisMAPK signalingISG15SNW1


Description

No description

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Quality Tags

Ontology Terms

 

Bibliography

  1. van der Lee R, Feng Q, Langereis MA, Ter Horst R, Szklarczyk R, Netea MG, Andeweg AC, van Kuppeveld FJ, Huynen MA; ''Integrative Genomics-Based Discovery of Novel Regulators of the Innate Antiviral Response.''; PLoS Comput Biol, 2015 PubMed Europe PMC Scholia

History

View all...
CompareRevisionActionTimeUserComment
123636view09:43, 7 August 2022EgonwModified title
123123view18:07, 4 July 2022EgonwMade four pathways clickable
106524view23:45, 5 September 2019KhanspersModified description
105798view22:48, 15 August 2019KhanspersModified description
104869view19:51, 21 June 2019AlexanderPicoModified description
104868view19:48, 21 June 2019AlexanderPicoModified title
104581view12:47, 2 June 2019YtModified title
88186view00:44, 30 July 2016AlexanderPicoAdded newly discovered viral RNA-host RLR components
88185view00:39, 30 July 2016AlexanderPicoOntology Term : 'viral infectious disease' added !
88184view00:38, 30 July 2016AlexanderPicoOntology Term : 'signaling pathway in the innate immune response' added !
88183view00:38, 30 July 2016AlexanderPicoOntology Term : 'signaling pathway' added !
88182view00:38, 30 July 2016AlexanderPicoModified description
88181view00:23, 30 July 2016AlexanderPicoAdded literature reference
88180view00:22, 30 July 2016AlexanderPicofixed complex position
88179view00:21, 30 July 2016AlexanderPicoNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
5'ppp-RNARna
ATG12GeneProductENSG00000145782 (Ensembl)
ATG5GeneProductENSG00000057663 (Ensembl)
AZI2GeneProductENSG00000163512 (Ensembl)
ApoptosisPathwayWP254 (WikiPathways)
CASP10GeneProductENSG00000003400 (Ensembl)
CASP8GeneProductENSG00000064012 (Ensembl)
CHUKGeneProductENSG00000213341 (Ensembl)
CXCL10GeneProductENSG00000169245 (Ensembl)
CXCL12GeneProductENSG00000107562 (Ensembl)
CXCL8GeneProductENSG00000169429 (Ensembl)
CYLDGeneProductENSG00000083799 (Ensembl)
DAKGeneProductENSG00000149476 (Ensembl)
DDX17GeneProductENSG00000100201 (Ensembl)
DDX3XGeneProductENSG00000215301 (Ensembl)
DDX3YGeneProductENSG00000067048 (Ensembl)
DDX58GeneProductENSG00000107201 (Ensembl)
DHX58GeneProductENSG00000108771 (Ensembl)
FADDGeneProductENSG00000168040 (Ensembl)
IFIH1GeneProductENSG00000115267 (Ensembl)
IFNA1GeneProductENSG00000197919 (Ensembl)
IFNB1GeneProductENSG00000171855 (Ensembl)
IFNEGeneProductENSG00000184995 (Ensembl)
IFNGGeneProductENSG00000111537 (Ensembl)
IFNKGeneProductENSG00000147896 (Ensembl)
IKBKBGeneProductENSG00000104365 (Ensembl)
IKBKEGeneProductENSG00000263528 (Ensembl)
IKBKGGeneProductENSG00000269335 (Ensembl)
IRF3GeneProductENSG00000126456 (Ensembl)
IRF7GeneProductENSG00000185507 (Ensembl)
ISG15GeneProductENSG00000187608 (Ensembl)
MAP3K1GeneProductENSG00000095015 (Ensembl)
MAP3K7GeneProductENSG00000135341 (Ensembl)
MAPK signalingPathwayWP382 (WikiPathways)
MAPK10GeneProductENSG00000109339 (Ensembl)
MAPK11GeneProductENSG00000185386 (Ensembl)
MAPK12GeneProductENSG00000188130 (Ensembl)
MAPK13GeneProductENSG00000156711 (Ensembl)
MAPK14GeneProductENSG00000112062 (Ensembl)
MAPK8GeneProductENSG00000107643 (Ensembl)
MAPK9GeneProductENSG00000050748 (Ensembl)
MAVSGeneProductENSG00000088888 (Ensembl)
NFKB1GeneProductENSG00000109320 (Ensembl)
NFKBIAGeneProductENSG00000100906 (Ensembl)
NFKBIBGeneProductENSG00000104825 (Ensembl)
NLRX1GeneProductENSG00000160703 (Ensembl)
OTUD5GeneProductENSG00000068308 (Ensembl)
PIN1GeneProductENSG00000127445 (Ensembl)
RELAGeneProductENSG00000173039 (Ensembl)
RIPK1GeneProductENSG00000137275 (Ensembl)
RNF125GeneProductENSG00000101695 (Ensembl)
SIKE1GeneProductENSG00000052723 (Ensembl)
SNW1GeneProductENSG00000100603 (Ensembl)
TANKGeneProductENSG00000136560 (Ensembl)
TBK1GeneProductENSG00000183735 (Ensembl)
TBKBP1GeneProductENSG00000198933 (Ensembl)
TMEM173GeneProductENSG00000184584 (Ensembl)
TNFAProteinENSG00000232810 (Ensembl)
TRADDGeneProductENSG00000102871 (Ensembl)
TRAF2GeneProductENSG00000127191 (Ensembl)
TRAF3GeneProductENSG00000131323 (Ensembl)
TRAF6GeneProductENSG00000175104 (Ensembl)
TRIM25GeneProductENSG00000121060 (Ensembl)
Ub-mediated proteolysisPathwayWP183 (WikiPathways)
long dsRNARna
short dsRNARna

Annotated Interactions

No annotated interactions

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