Complement and coagulation cascades (Canis familiaris)

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Muscle contraction,Chemotaxis,Phagocyte recruitmentInflammation, etc.Vascular injuryClassical PathwayC3b/BbDegredationFibrinolytic systemZymosan,insulin, etc.membrane attack complexCell lysisMediatorsfibrin degredationproductsC4aC5aLectin PathwayC3b/4b, C3b, C3dCoagulation CascadeC3ConvertaseComplement CascadeAntibody/antigencomplexExtrinsic pathwayCross-linkedfibrin polymerKinin kallikrein systemCell adhesion,migration,profileration, etcAlternative PathwayClotC4b/2aCell adhesion,migration,profileration, etcC3aPlatelet, monocyte,lymphocyte,endothelial cells,smooth muscle cellsactivation, etcC3bThrombinCollagen,basement membrane,activated platelets, etc.TFPIDaf2SERPIND1PLAURC1SF8F12CD59AC3AR1C1QCSERPINE1BradykininDaf1CFHF3PLGC3C1QBBDKRB1VWFC5AR1CFIF13BF2R109821C1RPLATC4PROS1F9THBDSERPINA1C6FGBKNG1F5SERPINC1C2H2-BFLOC480771CR1C7C1QAFibrin monomerCR2F2HcCRRYPROCC4BPF10ADNKLKB1MASP2SERPINF2A2MSERPINA5CPB2MBL1C8GMASP1F7PLAUSERPING1C9


Description

No description

Comments

GenMAPP notes 
http://www.genome.jp/dbget-bin/get pathway?org name=mmu&mapno=04610
GenMAPP remarks 
Adapted from KEGG (see notes)
HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP558(r22582) with a 67% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

  1. ''''; https://www.genome.jp/dbget-bin/www_bget?pathway+map04610,

History

View all...
CompareRevisionActionTimeUserComment
122648view04:15, 26 April 2022Khanspersupdating with latest converted content
122581view09:59, 18 April 2022EweitzModified title
89195view03:58, 23 August 2016AriuttaOntology Term : 'hemostasis pathway' added !
89194view03:58, 23 August 2016AriuttaOntology Term : 'complement system pathway' added !
89193view03:56, 23 August 2016AriuttaOntology Term : 'coagulation cascade pathway' added !
71454view19:16, 17 October 2013MaintBotAutomated update of data sources
68513view21:57, 5 July 2013MaintBotUpdated to 2013 gpml schema
40665view21:49, 1 March 2011MaintBotRemoved redundant pathway information and comments
38706view19:28, 23 September 2010AlexanderPico
33957view18:23, 9 December 2009MaintBotAutomatic update of empty xrefs
32259view12:59, 15 August 2009MaintBotFixed text labels
31783view12:12, 14 August 2009MaintBotFixed group labels
31286view20:04, 13 August 2009MaintBotFixed text labels
30741view23:03, 29 July 2009MaintBotNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
A2MGeneProduct477699 (Entrez Gene)
ADNGeneProduct
BDKRB1GeneProduct490847 (Entrez Gene)
BradykininMetabolite
C1QAGeneProduct478194 (Entrez Gene)
C1QBGeneProduct487381 (Entrez Gene)
C1QCGeneProduct487382 (Entrez Gene)
C1RGeneProduct477707 (Entrez Gene)
C1SGeneProduct486714 (Entrez Gene)
C2GeneProduct
C3GeneProduct476728 (Entrez Gene)
C3AR1GeneProduct486704 (Entrez Gene)
C4GeneProduct
C4BPGeneProduct
C5AR1GeneProduct442974 (Entrez Gene)
C6GeneProduct479348 (Entrez Gene)
C7GeneProduct489221 (Entrez Gene) MGI:88235 LL:109828
C8GGeneProduct480672 (Entrez Gene)
C9GeneProduct479354 (Entrez Gene)
CD59AGeneProduct
CFHGeneProduct478952 (Entrez Gene)
CFIGeneProduct478515 (Entrez Gene)
CPB2GeneProduct608910 (Entrez Gene)
CR1GeneProduct609328 (Entrez Gene)
CR2GeneProduct490269 (Entrez Gene)
CRRYGeneProduct
Daf1GeneProduct
Daf2GeneProduct
F10GeneProduct476993 (Entrez Gene)
F12GeneProduct489090 (Entrez Gene)
F13BGeneProduct490261 (Entrez Gene)
F2GeneProduct
F2RGeneProduct488942 (Entrez Gene)
F3GeneProduct490153 (Entrez Gene)
F5GeneProduct
F7GeneProduct607661 (Entrez Gene)
F8GeneProduct403875 (Entrez Gene)
F9GeneProduct404015 (Entrez Gene)
FGBGeneProduct475472 (Entrez Gene)
Fibrin monomerMetabolite
H2-BFGeneProduct
HcGeneProduct
KLKB1GeneProduct475624 (Entrez Gene)
KNG1GeneProduct478666 (Entrez Gene)
LOC480771GeneProduct480771 (Entrez Gene)
MASP1GeneProduct488121 (Entrez Gene)
MASP2GeneProduct
MBL1GeneProduct
PLATGeneProduct482840 (Entrez Gene)
PLAUGeneProduct403426 (Entrez Gene)
PLAURGeneProduct476446 (Entrez Gene)
PLGGeneProduct403602 (Entrez Gene)
PROCGeneProduct476104 (Entrez Gene)
PROS1GeneProduct478529 (Entrez Gene)
SERPINA1GeneProduct480422 (Entrez Gene)
SERPINA5GeneProduct480424 (Entrez Gene)
SERPINC1GeneProduct480066 (Entrez Gene)
SERPIND1GeneProduct
SERPINE1GeneProduct403476 (Entrez Gene)
SERPINF2GeneProduct611266 (Entrez Gene)
SERPING1GeneProduct475966 (Entrez Gene)
TFPIGeneProduct403921 (Entrez Gene)
THBDGeneProduct474355 (Entrez Gene)
VWFGeneProduct399544 (Entrez Gene)
109821GeneProduct

Annotated Interactions

No annotated interactions
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