Lipid metabolism pathway (Homo sapiens)

From WikiPathways

Description

Quality Tags

Ontology Terms

Bibliography

1. Zhang X, Saarinen AM, Hitosugi T, Wang Z, Wang L, Ho TH, Liu J; ''Inhibition of intracellular lipolysis promotes human cancer cell adaptation to hypoxia.''; Elife, 2017 PubMed Europe PMC Scholia
2. Asfa AS, Qiu B, Wee S, Choi H, Gunaratne J, Tergaonkar V; ''Phosphoprotein network analysis of white adipose tissues unveils deregulated pathways in response to high-fat diet.''; Sci Rep, 2016 PubMed Europe PMC Scholia
3. Grahn TH, Zhang Y, Lee MJ, Sommer AG, Mostoslavsky G, Fried SK, Greenberg AS, Puri V; ''FSP27 and PLIN1 interaction promotes the formation of large lipid droplets in human adipocytes.''; Biochem Biophys Res Commun, 2013 PubMed Europe PMC Scholia

History

View all...

Compare	Revision	Action	Time	User	Comment
	135480	view	05:10, 16 September 2024	Egonw	Take the neutral citric acid with more mappings
	128420	view	17:11, 4 February 2024	Eweitz	Modified description
	128419	view	17:04, 4 February 2024	Eweitz	Slightly thin arrow
	128418	view	17:02, 4 February 2024	Eweitz	Economize layout, standardize case
	117154	view	09:44, 18 May 2021	Eweitz	Modified title
	106630	view	20:55, 12 September 2019	Khanspers	Modified description
	105636	view	05:05, 10 August 2019	Khanspers	Modified description
	96169	view	12:30, 22 February 2018	Mkutmon	added link from PLIN1 to HSL
	96168	view	12:20, 22 February 2018	Mkutmon	Updated layout and complexes
	95533	view	09:16, 21 December 2017	Egonw	Added a recent protein found that inhibits ATGL.
	94914	view	00:11, 13 October 2017	Khanspers	Modified description
	94741	view	15:09, 5 October 2017	Mkutmon	fix unconnected line
	91544	view	06:35, 10 March 2017	Egonw	Added the last few metabolite IDs.
	91543	view	20:15, 9 March 2017	Egonw	Added a few metabolite IDs.
	91542	view	18:53, 9 March 2017	Egonw	Typo.
	91437	view	20:06, 24 February 2017	Susan	Ontology Term : 'lipid metabolic pathway' added !
	91436	view	20:05, 24 February 2017	Susan	Ontology Term : 'obesity' added !
	91435	view	20:04, 24 February 2017	Susan	Ontology Term : 'white fat cell' added !
	91400	view	08:03, 20 February 2017	Mkutmon	New pathway

External references

DataNodes

View all...

Name	Type	Database reference	Comment
ABHD5	GeneProduct	ENSG00000011198 (Ensembl)
ACACA	GeneProduct	ENSG00000278540 (Ensembl)
ACLY	GeneProduct	ENSG00000131473 (Ensembl)
ACSBG1	GeneProduct	ENSG00000103740 (Ensembl)
ACSS2	GeneProduct	ENSG00000131069 (Ensembl)
AKT1	GeneProduct	ENSG00000142208 (Ensembl)
AKT2	GeneProduct	ENSG00000105221 (Ensembl)
AKT3	GeneProduct	ENSG00000117020 (Ensembl)
ATGL	GeneProduct	ENSG00000177666 (Ensembl)
Acetate	Metabolite
AcetylCoA(cyt)	Metabolite
AcetylCoA(mit)	Metabolite
BCAA	Metabolite
BCFA	Metabolite
BCKDHA	GeneProduct	ENSG00000248098 (Ensembl)
Citrate	Metabolite
DAG	Metabolite
FASN	GeneProduct	ENSG00000169710 (Ensembl)
Fata acid elongation	Pathway
FreeFA	Metabolite
Glycerolipid metabolism	Pathway
Glycerophospholipid metabolism	Pathway
HSL	GeneProduct	ENSG00000079435 (Ensembl)
MAG	Metabolite
MalonylCoA	Metabolite
PDHA1	GeneProduct	ENSG00000131828 (Ensembl)
PRKAA1	GeneProduct	ENSG00000132356 (Ensembl)
PRKAA2	GeneProduct	ENSG00000162409 (Ensembl)
PRKAB1	GeneProduct	ENSG00000111725 (Ensembl)
PRKAB2	GeneProduct	ENSG00000131791 (Ensembl)
PRKACA	GeneProduct	ENSG00000072062 (Ensembl)
PRKACB	GeneProduct	ENSG00000142875 (Ensembl)
PRKACG	GeneProduct	ENSG00000165059 (Ensembl)
PRKAG1	GeneProduct	ENSG00000181929 (Ensembl)
PRKAG2	GeneProduct	ENSG00000106617 (Ensembl)
PRKAG3	GeneProduct	ENSG00000115592 (Ensembl)
PRKAR1A	GeneProduct	ENSG00000108946 (Ensembl)
PRKAR1B	GeneProduct	ENSG00000188191 (Ensembl)
PRKAR2A	GeneProduct	ENSG00000114302 (Ensembl)
PRKAR2B	GeneProduct	ENSG00000005249 (Ensembl)
Palimitate	Metabolite
PalimitateCoA	Metabolite
Pyruvate	Metabolite
TAG	Metabolite

Annotated Interactions

No annotated interactions