Canonical wnt signaling (Danio rerio)

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1transcriptionmouse (cells)xenopusnoncanonocal wnt / cytoskeletontumorszebrafishnodaldrosophillaBMPwnt-homepagenot the wnt-homepagehuman colon cancermouse developmentfgfwnt16neurogenin 1dkk1ctbp2lengrailed 2aspry4cyclinD1fzd7bbmp4bglapermjagged 1bephrin B1rac3wnt5bwnt4beve1RhoAbPKCctbp2E-cadherinRhoAccspg2a /versicansfzd5fzd3c-junid2bcamk2dwnt2tclfzd8asfrp1awnt4awnt10afzd9otx1bozrac2chdsall4drl / rykE12 / tcf3lef1jagged 1aspry2pontin52 / ruvbl1GBPfzd10smarca4birc5afibronectin 1fibronectin 1bfzd4cdc42lRhoAabeta-catenin1sfzd1fgf4vegfcprkcb1sfrp5LRP5stripe / egr2bmitfafz12otx2dab2dvl3fzd8cmkp3sox2ppp2r5e1ccnd1cdc42l2par1beta-catenin2RhoAefgf20bsqtirx3awnt1wnt7actnnb2wnt8bdvl2prkcb1lirx3bTak1wisp2axin2 / conductinpitx2bhoxb1bnkd1VEGFalim1wnt3lpitx2aconnexin 43rac1camk1gcdh1 / E-cadherinedasox17dact1 / dapper1sfrp2rfzd8bbeta-catenin2fgf18lntlNLKengrailed 1aid2arhoua /wrch1wnt7periostinck2a2smobmp2bAPCgroucho1birc5btcf3b / tcf7l1bppp2r5e2foxN1nos2wif1dldbeta-catenin2ikbkg / nemovedRhoAdtcf3 / tcf7l1aaxin1fzd2beta-catenin1c-mycwnt11dact2 / drapperprkcick2bdact2 / dapper2ctbp1prkcl2fgf3tcf-1 / elk4CBP / p300groucho3cdc42wnt10bventdlagroucho2twistmycaldlrfzd7afrzbfgf18fgf20atcf1sp5tcf4sfrp2lvoxoeprunx2bCKI-alphafzd1sp5lgsk3bRA receptor gcatenin-beta 1follistatinubxd1wnt11raxin2sox9aengrailed 1bicatcdx4ck2a1cdx1apeaNLKptgs2sox9bruvbl2 / reptingscfgf8endothelin 1engrailed 2bwnt2bwnt8asfrp2ctnnb1egfrgata2runx2ametlef


Description

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Bibliography

  1. S.F. Gabby Krens, Maximiliano Corredor-Adámez, Shuning He, B. Ewa Snaar- Jagalska, Herman P Spaink; ''ERK1 and ERK2 MAPK are key regulators of distinct gene sets in zebrafish embryogenesis''; BMC Genomics 2008, 9:196 , 2008 PubMed Europe PMC Scholia

History

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CompareRevisionActionTimeUserComment
118436view14:42, 27 May 2021EgonwReplaced the remaining UniGene IDs
118422view14:21, 27 May 2021EgonwAnother batch
118403view14:11, 27 May 2021EgonwFixed an author name
118400view14:10, 27 May 2021EgonwA bunch more UniGene conversions
118378view13:52, 27 May 2021EgonwMore UniGene replacements
118361view13:42, 27 May 2021EgonwReplaced the first few UniGene IDs
96484view16:23, 15 March 2018Fehrhartfixed some connections
96481view16:20, 15 March 2018FehrhartModified description
95726view20:31, 18 January 2018AlexanderPicoupdated retired unigene id
95725view20:31, 18 January 2018AlexanderPicofixed xref
95724view20:30, 18 January 2018AlexanderPicofixed xref
95723view20:28, 18 January 2018AlexanderPicofixed xref
95722view20:26, 18 January 2018AlexanderPicofixed xref
95721view20:25, 18 January 2018AlexanderPicofixed xref
95720view20:24, 18 January 2018AlexanderPicofixed xref
95719view20:22, 18 January 2018AlexanderPicofixed xref
95718view20:21, 18 January 2018AlexanderPicofixed xref
95717view20:20, 18 January 2018AlexanderPicofixed xref
95716view20:19, 18 January 2018AlexanderPicofixed xref
95715view20:18, 18 January 2018AlexanderPicofixed xref
95714view20:17, 18 January 2018AlexanderPicofixed xref
95713view20:16, 18 January 2018AlexanderPicofixed xref
95712view20:15, 18 January 2018AlexanderPicofixed xref
95711view20:13, 18 January 2018AlexanderPicoupdated retired unigene id
95710view20:11, 18 January 2018AlexanderPicofixed xref
95709view20:10, 18 January 2018AlexanderPicoupdated retired unigene id
95708view20:08, 18 January 2018AlexanderPicofixed xref
95707view20:07, 18 January 2018AlexanderPicofixed xref
95706view20:06, 18 January 2018AlexanderPicofixed xref
95705view20:05, 18 January 2018AlexanderPicofixed xref
95704view20:03, 18 January 2018AlexanderPicofixed xref
95703view20:02, 18 January 2018AlexanderPicoRemoved stray characters and updated xref
74475view04:40, 25 April 2014EgonwFixed a PubMed ID.
71977view00:26, 24 October 2013MaintBotremoved data source from nodes without identifier
70150view21:36, 12 July 2013MaintBotupdated to 2013 schema
70149view21:35, 12 July 2013MaintBotModified title
70077view09:30, 12 July 2013Mkutmonfixed unconnected lines
67098view10:06, 26 June 2013Christine ChichesterOntology Term : 'canonical Wnt signaling pathway' added !
40794view22:16, 1 March 2011MaintBotRemoved redundant pathway information and comments
21872view11:32, 14 November 2008MaintBot[[Pathway:Danio rerio:Wnt Signaling canonical]] moved to [[Pathway:WP566]]: Moved to stable identifier
16299view20:45, 17 June 2008Khanspers[[Pathway:Danio rerio:Dr Wnt-signaling canonical]] moved to [[Pathway:Danio rerio:Wnt Signaling canonical]]: Removed species code prefix from pathway name
14269view07:09, 22 May 2008SFGKrensModified categories
14038view08:02, 21 May 2008SFGKrensNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
APCGeneProduct386762 (Entrez Gene)
CBP / p300GeneProductDr.75365 (UniGene)
CKI-alphaGeneProduct
E-cadherinGeneProductDr.78411 (UniGene)
E12 / tcf3GeneProductDr.20061 (UniGene)
GBPGeneProductDr.81277 (UniGene)
LRP5GeneProduct554087 (Entrez Gene)
NLKGeneProduct405892 (Entrez Gene)
PKCGeneProduct334077 (Entrez Gene)
RA receptor gGeneProduct30606 (Entrez Gene)
RhoAaGeneProductDr.32765 (UniGene)
RhoAbGeneProduct336001 (Entrez Gene)
RhoAcGeneProductDr.5516 (UniGene)
RhoAdGeneProduct436718 (Entrez Gene)
RhoAeGeneProductDr.75611 (UniGene)
Tak1GeneProduct553788 (Entrez Gene)
VEGFaGeneProductDr.597 (UniGene)
axin1GeneProduct57931 (Entrez Gene) masterblind
axin2 / conductinGeneProduct58080 (Entrez Gene)
axin2GeneProduct58080 (Entrez Gene)
beta-catenin1GeneProduct30265 (Entrez Gene)
beta-catenin2GeneProduct324004 (Entrez Gene)
beta-catenin2GeneProductDr.29035 (UniGene)
bglapGeneProduct494531 (Entrez Gene)
birc5aGeneProduct373110 (Entrez Gene)
birc5bGeneProduct246726 (Entrez Gene)
bmp2bGeneProduct30632 (Entrez Gene)
bmp4GeneProduct30612 (Entrez Gene)
bozGeneProduct30170 (Entrez Gene)
c-junGeneProductDr.1064 (UniGene)
c-mycGeneProductDr.1 (UniGene)
camk1gGeneProduct335654 (Entrez Gene)
camk2dGeneProductDr.12561 (UniGene)
catenin-beta 1GeneProduct30265 (Entrez Gene) ’catenin (cadherin-associated protein), beta 1 ’
ccnd1GeneProduct30222 (Entrez Gene)
cdc42GeneProduct336839 (Entrez Gene)
cdc42l2GeneProduct556226 (Entrez Gene)
cdc42lGeneProductDr.1474 (UniGene)
cdh1 / E-cadherinGeneProductDr.78411 (UniGene)
cdx1aGeneProductDr.84223 (UniGene)
cdx4GeneProduct30330 (Entrez Gene)
chdGeneProductDr.75804 (UniGene)
ck2a1GeneProduct30502 (Entrez Gene)
ck2a2GeneProduct30488 (Entrez Gene)
ck2bGeneProduct30428 (Entrez Gene)
connexin 43GeneProduct30236 (Entrez Gene)
cspg2a /versicanGeneProduct30299 (Entrez Gene)
ctbp1GeneProduct65229 (Entrez Gene)
ctbp2GeneProduct65230 (Entrez Gene)
ctbp2lGeneProduct548605 (Entrez Gene)
ctnnb1GeneProduct30265 (Entrez Gene)
ctnnb2GeneProductDr.29035 (UniGene)
cyclinD1GeneProduct30222 (Entrez Gene)
dab2GeneProduct404040 (Entrez Gene)
dact1 / dapper1GeneProduct405799 (Entrez Gene)
dact2 / dapper2GeneProduct337795 (Entrez Gene)
dact2 / drapperGeneProduct337795 (Entrez Gene) ’dapper homolog 2, antagonist of beta-catenin’
dkk1GeneProduct30197 (Entrez Gene)
dlaGeneProduct30131 (Entrez Gene)
dldGeneProductDr.75102 (UniGene)
drl / rykGeneProduct30167 (Entrez Gene)
dvl2GeneProduct323630 (Entrez Gene) deshevelled2
dvl3GeneProduct80972 (Entrez Gene) deshevelled3
edaGeneProductZDB-GENE-050107-6 (ZFIN)
egfrGeneProductDr.82227 (UniGene)
endothelin 1GeneProductDr.4076 (UniGene)
engrailed 1aGeneProduct30244 (Entrez Gene)
engrailed 1bGeneProduct30233 (Entrez Gene)
engrailed 2aGeneProduct30243 (Entrez Gene)
engrailed 2bGeneProduct30238 (Entrez Gene)
ephrin B1GeneProduct114377 (Entrez Gene)
ermGeneProduct30452 (Entrez Gene)
eve1GeneProduct30335 (Entrez Gene)
fgf18GeneProductDr.72277 (UniGene)
fgf18lGeneProduct497639 (Entrez Gene)
fgf20aGeneProduct559630 (Entrez Gene)
fgf20bGeneProduct564770 (Entrez Gene)
fgf3GeneProduct30549 (Entrez Gene)
fgf4GeneProduct60311 (Entrez Gene)
fgf8GeneProduct30538 (Entrez Gene)
fibronectin 1GeneProduct58034 (Entrez Gene)
fibronectin 1bGeneProduct334613 (Entrez Gene)
follistatinGeneProduct30235 (Entrez Gene)
foxN1GeneProduct266748 (Entrez Gene)
frzbGeneProduct30119 (Entrez Gene)
fz12GeneProduct30275 (Entrez Gene)
fzd10GeneProduct30366 (Entrez Gene)
fzd1GeneProduct30365 (Entrez Gene)
fzd2GeneProduct30370 (Entrez Gene)
fzd3GeneProduct30371 (Entrez Gene)
fzd4GeneProduct30363 (Entrez Gene)
fzd7aGeneProductDr.4823 (UniGene)
fzd7bGeneProduct30412 (Entrez Gene)
fzd8aGeneProduct58073 (Entrez Gene)
fzd8cGeneProduct30364 (Entrez Gene)
fzd9GeneProduct58023 (Entrez Gene)
gata2GeneProduct30480 (Entrez Gene)
groucho1GeneProductDr.23459 (UniGene)
groucho2GeneProduct30206 (Entrez Gene)
groucho3GeneProduct83411 (Entrez Gene)
gscGeneProductDr.289 (UniGene)
gsk3bGeneProduct30654 (Entrez Gene)
hoxb1bGeneProduct30374 (Entrez Gene)
icatGeneProduct58117 (Entrez Gene) beta-catenin-interacting protein
id2aGeneProduct266599 (Entrez Gene)
id2bGeneProduct321364 (Entrez Gene)
ikbkg / nemoGeneProductDr.6051 (UniGene)
irx3aGeneProduct30520 (Entrez Gene)
irx3bGeneProductDr.30395 (UniGene)
jagged 1aGeneProduct140421 (Entrez Gene)
jagged 1bGeneProduct140423 (Entrez Gene)
ldlrGeneProduct387529 (Entrez Gene)
lef1GeneProductDr.64686 (UniGene)
lefGeneProductDr.64686 (UniGene)
lim1GeneProduct30463 (Entrez Gene)
metGeneProductDr.83673 (UniGene)
mitfaGeneProduct30080 (Entrez Gene)
mkp3GeneProduct353314 (Entrez Gene)
mycaGeneProductDr.1 (UniGene)
neurogenin 1GeneProduct30239 (Entrez Gene)
nkd1GeneProduct751108 (Entrez Gene)
nos2GeneProduct404036 (Entrez Gene)
ntlGeneProduct30399 (Entrez Gene)
oepGeneProductDr.52009 (UniGene)
otx1GeneProduct30500 (Entrez Gene)
otx2GeneProduct30501 (Entrez Gene)
par1GeneProductDr.81253 (UniGene)
peaGeneProductDr.75840 (UniGene)
periostinGeneProductDr.30157 (UniGene)
pitx2aGeneProduct30164 (Entrez Gene)
pitx2bGeneProductZDB-GENE-030912-12 (ZFIN)
pontin52 / ruvbl1GeneProduct317679 (Entrez Gene)
ppp2r5e1GeneProductDr.15883 (UniGene)
ppp2r5e2GeneProductDr.79532 (UniGene)
prkcb1GeneProduct393953 (Entrez Gene)
prkcb1lGeneProduct394004 (Entrez Gene)
prkciGeneProduct117507 (Entrez Gene)
prkcl2GeneProductDr.35935 (UniGene)
ptgs2GeneProduct246227 (Entrez Gene)
rac1GeneProduct327204 (Entrez Gene)
rac2GeneProduct415151 (Entrez Gene)
rac3GeneProduct437027 (Entrez Gene)
rfzd8bGeneProduct58072 (Entrez Gene)
rhoua /wrch1GeneProduct492802 (Entrez Gene)
runx2aGeneProduct405784 (Entrez Gene)
runx2bGeneProductDr.30423 (UniGene)
ruvbl2 / reptinGeneProduct317678 (Entrez Gene)
sall4GeneProductZDB-GENE-060328-2 (Other)
sfrp1aGeneProductDr.105557 (UniGene)
sfrp2GeneProduct566878 (Entrez Gene)
sfrp2GeneProductDr.76476 (UniGene)
sfrp2lGeneProductZDB-GENE-061122-2 (ZFIN)
sfrp5GeneProductDr.86566 (UniGene)
sfzd1GeneProduct402843 (Entrez Gene) secreted frizzled-related protein
sfzd5GeneProduct117510 (Entrez Gene) secreted frizzled-related protein
smarca4GeneProduct353295 (Entrez Gene)
smoGeneProductDr.75382 (UniGene)
sox17GeneProduct30544 (Entrez Gene)
sox2GeneProduct378723 (Entrez Gene)
sox9aGeneProduct60641 (Entrez Gene)
sox9bGeneProduct60642 (Entrez Gene)
sp5GeneProductDr.78633 (UniGene)
sp5lGeneProduct324261 (Entrez Gene)
spry2GeneProduct335098 (Entrez Gene)
spry4GeneProduct114437 (Entrez Gene)
sqtGeneProduct30153 (Entrez Gene)
stripe / egr2bGeneProduct30190 (Entrez Gene)
tcf-1 / elk4GeneProductDr.76746 (UniGene)
tcf1GeneProduct266961 (Entrez Gene)
tcf3 / tcf7l1aGeneProductDr.79155 (UniGene)
tcf3b / tcf7l1bGeneProductDr.8108 (UniGene)
tcf4GeneProduct30510 (Entrez Gene)
tclGeneProduct386615 (Entrez Gene) secreted frizzled-related protein
twistGeneProduct30175 (Entrez Gene)
ubxd1GeneProduct327469 (Entrez Gene)
vedGeneProduct368201 (Entrez Gene)
vegfcGeneProductDr.88903 (UniGene)
ventGeneProduct64810 (Entrez Gene)
voxGeneProduct64807 (Entrez Gene)
wif1GeneProduct30476 (Entrez Gene) wnt inhibitory factor 1
wisp2GeneProductZDB-GENE-060223-1 (ZFIN)
wnt10aGeneProductDr.342 (UniGene)
wnt10bGeneProductDr.88562 (UniGene)
wnt11GeneProduct30139 (Entrez Gene) silberblick
wnt11rGeneProductDr.76466 (UniGene)
wnt16GeneProductDr.87285 (UniGene)
wnt1GeneProductDr.85371 (UniGene)
wnt2GeneProduct30127 (Entrez Gene)
wnt2bGeneProductDr.88309 (UniGene)
wnt3lGeneProductDr.92208 (UniGene)
wnt4aGeneProductDr.385 (UniGene)
wnt4bGeneProductDr.81321 (UniGene)
wnt5bGeneProductDr.389 (UniGene)
wnt7GeneProduct60633 (Entrez Gene)
wnt7aGeneProduct565714 (Entrez Gene)
wnt8aGeneProduct30122 (Entrez Gene)
wnt8bGeneProduct30144 (Entrez Gene)

Annotated Interactions

No annotated interactions

Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP566"
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