Melanogenesis (Homo sapiens)
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Description
Melanogenesis is the process by which melanocytes produce melanin, a pigment found in the skin, eyes, and hair. Melanogenesis leads to a long-lasting pigmentation, which is in contrast to the pigmentation that originates from oxidation of already-existing melanin.
Cutaneous melanin pigment plays a critical role in camouflage, mimicry, social communication, and protection against harmful effects of solar radiation. Melanogenesis is under complex regulatory control by multiple agents.
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DataNodes
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| Name | Type | Database reference | Comment |
|---|---|---|---|
| Active TGF-B | Protein | ||
| Active VEGF | Protein | ||
| ET-1 | Protein | ||
| Estrogen | Protein | ||
| MITF | Protein | ||
| Melanogenesis | Pathway | ||
| PAI-1 | Protein | ||
| Plasmin | Metabolite | CHEBI:53373 (ChEBI)  | |
| Plasminogen | Protein | P00747 (Uniprot-TrEMBL) | |
| SCF | Protein | ||
| Tranexamic Acid | Protein | ||
| tPA | Protein |
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