Pilocytic astrocytoma (Bos taurus)

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RAF1MEKTRANSFER FACTORCYTOPLASAMCytoplasmic targetsERKCell growth,survival,motilityNUCLEUSBRAFSOS1RAS:GTPNF1GRB2RTKPTPN11RAS:GDP


Description

In this pathway shows the signaling in the development and behavior of the disease. receptor tyrosine kinase(rtk) is expressed in tumor endothelial cells of adult glioblastomas.NF1 and BRAF genes induced the tumor growth.

Comments

HomologyConvert 
This pathway was inferred from Homo sapiens pathway WP2253(74520) with a 100.0% conversion rate.

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Quality Tags

Ontology Terms

 

Bibliography

No bibliography


History

CompareRevisionActionTimeUserComment
105919view11:45, 16 August 2019MaintBotHMDB identifier normalization
97038view14:52, 26 April 2018AdoBioInfoConnect dem lines init.
80671view15:21, 30 June 2015MkutmonNew pathway

External references

DataNodes

View all...
NameTypeDatabase referenceComment
GRB2GeneProductENSBTAG00000004736 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000177885
NF1GeneProductENSBTAG00000011829 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000196712
PTPN11GeneProductENSBTAG00000002048 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000179295
RAS:GDPMetaboliteHMDB00960 (HMDB)
RAS:GTPMetaboliteHMDB01440 (HMDB)
RTKMetabolite
SOS1GeneProductENSBTAG00000011643 (Ensembl) HomologyConvert: Homo sapiens to Bos taurus: Original ID = En:ENSG00000115904

Annotated Interactions

No annotated interactions
Retrieved from "https://classic.wikipathways.org/index.php/Pathway:WP3122"
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